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Showing 1 to 20 of 130 for “"Amphetamine"”.
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Differential pharmacology of amphetamine enantiomers
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Alterations in executive functioning induced by repeated amphetamine exposure
Chronic exposure to psychostimulants such as amphetamine (AMPH) can induce long-term disruptions in cognition via actions on prefrontal cortex dopamine. Previous work has shown that two types of executive functions, set shifting and working memory (WM), are disrupted by AMPH sensitization and that …
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Studies into Amphetamine-Induced Unconditioned Behaviour in the Rat.
Previous work on the unconditioned effects of amphetamine in rats has examined qualitative changes in behaviours which become stereotyped and quantitative changes in locomotion. Stereotyped behaviours have been adopted as a model of raised caudate-putameri function whilst locomotion has been …
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Assessment of sex differences and amphetamine on schedule-induced polydipsia
<p>Amphetamine (AMPH) is one of the most common psychotropic drugs abused in the United States. Its major pharmacological effect is to increase synaptic dopamine levels in the mesolimbic reward pathway, which in turn causes behavioral effects in animals, and subjective effects in humans. These …
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Alcohol and amphetamine dependencies convoluted with anorexia and bulimia nervosa
… that some individuals with alcohol and amphetamine addictions are initially motivated to use alcohol and amphetamines because of underlying issues involving body dissatisfaction and weight reduction associated with Anorexia and Bilimia Nervosa. Current literature reveals similarities …
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Cocaine- and Amphetamine-Regulated Transcript Peptide Attenuates Baroreflex in the Rat.
<p>Cocaine- and amphetamine-regulated transcript (CART) was first identified in the rat striatum where levels were upregulated following cocaine or amphetamine administration. A dense plexus of CART-immunoreactive fibers is noted in the nucleus of the solitary tract (NTS). Results from …
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Impurity profiling and synthesis of precursors to the hallucinogenic amphetamine DOB
DOB (4‐bromo‐2,5‐dimethoxyamphetamine) is a newly emerging hallucinogenic amphetamine that sparked serious health warnings in Ireland, following its first seizure back in 2003. Known more commonly as “snowball”, this drug is highly potent and may be used as a substitute to ecstasy (MDMA) and …
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Methamphetamine and amphetamine differentially affect associative learning: behavioral and neurobiological correlates
… in the effects of two psychostimulants; methamphetamine (METH) and amphetamine (AMPH). These drugs were chosen because, while structurally very similar, they have differing abuse liabilities. Some of the disparities in rates of use and abuse can be accounted for by availability, with METH …
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ELUCIDATING AMPHETAMINE ACTIONS AT THE DOPAMINE TERMINAL: POTENTIAL FOR COCAINE ADDICTION TREATMENT
The behavioral and neurochemical effects of amphetamine have been studied since the beginnings of neuroscience; however, many questions still remain as to its precise mechanisms of action on neurotransmission, and the resulting effects on behavior. Given that amphetamine is one of the most widely …
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Effects of morphine, d-amphetamine, and food deprivation on temporally organized behavior
… examined the effects of morphine and d-amphetamine on behavior that was temporally organized under several schedule arrangements. Two body weights were assessed for each experiment. Experiment 1 made use of fixed-interval (FI) schedules, the peak procedure, and a two-key (free-operant …
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Development of an analytical method for the organic impurity profiling of amphetamine
No abstract available.
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The effects of prior exposure to amphetamine on feeding behavior in rats
… was to explore the effects of prior exposure to amphetamine on subsequent stress-induced and free feeding of regular chow or palatable cereal. After treatment with 5 injections of either d-amphetamine (3 mg/kg IP) or saline, administered on alternate days, animals in Experiments 1 and 3 were …
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Repeated amphetamine exposure and the enduring consequences on behavioral and neural plasticity
Amphetamines (AMPH) are relatively unique amongst the category of psychoactive drugs, as they are both prescribed for therapeutic purposes at an alarmingly increasing rate and abused illicitly on account of their potential pleasurable effects (World Drug Report, 2012). In adult subjects, chronic …
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Effects of d -amphetamine and morphine on behavior maintained by fixed -interval schedules
The present experiments tested the effects of d-amphetamine and morphine on pigeons' responding during conventional and clocked FI schedules of food reinforcement. The first experiment compared performance between FI 5-min and continuously clocked FI 5-min components of a multiple schedule in which …
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Effects of intertrial interval and d-amphetamine on temporally organized behavior of pigeons
… the effects of intertrial interval and d-amphetamine on pecking of pigeons maintained by an interval bisection task. The side-tracking group responded based on the location of the key and the color-tracking group responded based on the color of the key. Intermediate stimulus durations were …
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Sex differences in PFC-related behavior after amphetamine exposure and across adolescent development
… be especially susceptible to the effects of amphetamine (AMPH) exposure on PFC function, given sex differences in the development of the PFC. Using a rodent model, this hypothesis was tested with two specific aims: (1) by determining whether there were age and sex differences in reward …
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The Effects of an Amphetamine on Measures of Intelligence and Learning Inmentally Retarded Adults
Made available in DSpace on 2014-12-10T21:07:03Z (GMT). No. of bitstreams: 1 7114860.pdf: 2725263 bytes, checksum: c7aa3d774516831d8e8c45635e9d1676 (MD5) Previous issue date: 1970
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The effects of repeated amphetamine exposure during adolescence on behavior and prefrontal cortex function
… are two commonly reported behavioral outcomes of amphetamine abuse. Individuals who begin using amphetamine during adolescence may have an increased risk of developing drug-related problems because of maturational changes in mesocorticolimbic circuitry that are specific to this stage of …
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