Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 49 for “"AmpC"”.
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Detection of Plasmid-Mediated AmpC b-Lactamases
Although plasmid-mediated AmpC b-lactamases were first reported in the late 1980's, most clinical laboratories and physicians remain unaware of their clinical importance. Current detection methods for organisms producing plasmid-mediated AmpC b-lactamases are time-consuming and …
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Mechanisms of Regulation and Resistance for Plasmid-Encoded ampC Beta-Lactamase Genes
… of high-level expression for the chromosomal AmpC genes from several organisms have been elucidated, whereas prior to data published from the work presented in this dissertation, the mechanisms of expression from plasmid-encoded ampC genes were unknown. The goal of the research presented in …
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EXTENDED-SPECTRUM Β-LACTAMASE-, AMPC- AND CARBAPENEMASE-PRODUCING BACTERIA IN DOGS AND CATS
… di β-lattamasi a spettro esteso (ESBL), AmpC e carbapenemasi, considerati indicatori chiave della resistenza antimicrobica nelle popolazioni batteriche. Campioni fecali di cani e gatti, sia domestici che randagi, sono stati analizzati per individuare la presenza, i meccanismi genetici e i …
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Mechanisms Involved in the Expression of the AmpC Beta-lactamase Gene blaCMY-2 in Escherichia coli
Enterobacteriaceae that express plasmid-encoded AmpC β-lactamases can be resistant to third generation cephalosporins and β-lactam/β-lactamase inhibitor combinations. Infections by these bacteria are associated with increased patient morbidity and mortality. Little is known about how …
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Detección y bases genéticas de beta-lactamasas AmpC y carbapenemasas en aislados clínicos y comensales de enterobacterias
… poseen genes codificantes de beta-lactamasas AmpC de manera intrínseca en su cromosoma y determinadas mutaciones en dichos genes puede provocar el aumento de su espectro de acción. Por otra parte, las enterobacterias son capaces de adquirir mecanismos de resistencia a diferentes familias de …
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The Influence of ampC Expression and Penicillin Binding Protein Binding on the Variation of ß-lactam Induction Potential in Three Genera of Enterobacteriaceae
… These organisms encode inducible, chromosomal AmpC ß-lactamases which can cause, if overproduced, resistance to all ß-lactams except the fourth generation cephalosporins and the carbapenems. The interaction of ß-lactams with penicillin binding proteins (PBPs) disrupts cell wall synthesis and in …
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Molecular detection, quantification and characterization of extended-spectrum β-lactamase (ESBL)- and AmpC-encoding genes in a cucumber agroecosystem
… primary focus of the study was on ESBL- and /or AmpC-producing Enterobacteriaceae due to their prevalence in fresh produce systems and the environment as stated by the World Health Organisation (WHO). In addition, plasmid-mediated AmpC β-lactamase (pAmpC)-producing Enterobacteriaceae have been …
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Régulation de la prolifération et de la différenciation des cellules épithéliales intestinales par les cascades MEK/ERK et AMPc/PKA
… de signalisation intracellulaires, MEK/ERK et AMPc/PKA, dans la prolifération et la différenciation des cellules épithéliales intestinales. Dans un premier temps, nous avons montré que la cascade MEK/ERK est nécessaire mais non suffisante à la prolifération des cellules épithéliales …
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Phase- and amplitude-coupling are tied by an intrinsic spatial organization but show divergent stimulus-related changes
… cycles. Conversely, amplitude coupling (AmpC), defined as coupling between the envelopes of two signals, reflects correlation of activation amplitude. Despite quantifying different electrophysiological properties, the relationship between PhC and AmpC remains largely unknown. We assessed …
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Pseudomonas aeruginosa OprD-Family Porins Facilitate Imipenem Translocation Resulting in AmpC β-Lactamase Induction Contributing to the Effectiveness of Imipenem/Relebactam
… outer membrane porin, OprD and overproduction of AmpC chromosomal β-lactamase. It is not known how relebactam potentiates imipenem when AmpC levels are low, nor how imipenem traffics into the cell in the absence of OprD. The purpose of this dissertation was to address these questions using three …
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Efeito do glutamato sobre a secreção da proteína S100B em cultura de astrócitos hipocampais
… dependente de síntese protéica e reduzida por Rp-AMPc e H-89, sugerindo o envolvimento da via AMPc/PKA, possivelmente sobre o elemento sensível ao AMPc no gene de S100B. Além disso, a privação de soro foi acompanhada por um aumento transitório do conteúdo intracelular de AMPc. Nossos resultados …
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Polynomial system identification modeling and adaptive model predictive control of arterial oxygen saturation in premature infants
… models, an adaptive model predictive controller (AMPC) was designed to adhere to clinical best practices to regulate the SpO2. Through a recursive polynomial model estimator (RPME), an ARX approximation of the unknown model's dynamics for the FiO2, HR, and RR relationship to the SpO2 could be used …
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Defining the Aetiology and Antimicrobial Susceptibility Patterns of the Predominant Bacteria Associated with Bloodstream Infections at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam
… extended spectrum Beta lactamases (ESBLs) and AmpC lactamases in the Enterobacteriaceae, methicillin-resistance genes in <i>Staphylococcus aureus</i>, carbapenemase-resistance genes in Gram-negative bacilli and vancomycin-resistance genes in enterococcus. Asian countries are also burdened with …
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Abundance of Antibiotic Resistance Genes in Feces Following Prophylactic and Therapeutic Intramammary Antibiotic Infusion in Dairy Cattle
… and subject to DNA extraction. The abundance of ampC, blaCMY-2, ermB, sul1, tetO, tetW, integrase-specific gene int1, and 16S rRNA were quantified using quantitative polymerase chain reaction (qPCR). The genes ampC and blaCMY-2 encode resistance to ß-lactam antibiotics, ermB to macrolides, sul1 …
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Surface triangulation and the downstream effects on surface flattening
… (RATCs) and axis of minimum principal curvature (AMPC) influenced triangulations, each which was found to have an impact on the triangulation dependant method of surface flattening. Right angle triangles (RATs) are commonly used throughout surface flattening. However, given a set of uniformly …
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Les dynamiques socio-économiques autour de l'Aire Marine Protégée Communautaire de Bamboung (Delta du Saloum, Sénégal): entre conservation et développement territorial
… marine protégée communautaire de Bamboung (AMPC), située dans la Réserve de Biosphère du delta du Saloum (Sénégal). Suite à la création de cette AMPC, nous avons choisi d’analyser la relative possibilité de concilier conservation et développement, analysée dans une approche territoriale et …
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Adaptive Predictive Controllers for Agile Quadrupedal Locomotion with Unknown Payloads
… integrates an adaptive model predictive control (AMPC) algorithm with a gradient-descent-based adaptive updating law applied to reduced-order locomotion (i.e., template) models. At the high level of the control hierarchy, an indirect adaptive law estimates unknown parameters of the reduced-order …
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Metagenomic Analysis of Antibiotic Resistance Genes in the Fecal Microbiome Following Therapeutic and Prophylactic Antibiotic Administration in Dairy Cows
… Gene Database (ARDB) via BLAST. Abundance of ampC, ermB, tetO, tetW, and 16S rRNA genes were determined using qPCR. All data were statistically analyzed with PROC GLIMMIX in SAS. Antibiotic treatment resulted in a shift in bacterial cell functions. Sequences associated with 'resistance to …
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Design and application of advanced control methods to gas turbines and networked systems
… approximate model predictive control (AMPC) and nonlinear model predictive control (NMPC), are presented along with the corresponding control algorithms. Since the parameters in a gain-scheduling PID controller change with the operating range, the need is apparent for a global nonlinear …
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Domestic greywater systems: a potential reservoir of antibiotic resistance genes transfer
… antibiotic resistance genes (ARGs) (vanA, ampC and aadA), as well as the intI1 gene, which serves as a marker of horizontal gene transfer. Phenotypic resistance was confirmed using the Kirby-Bauer disc diffusion method. Notably, high levels of resistance to ampicillin and kanamycin were …
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