Global ETD Search
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Showing 1 to 11 of 11 for “"Aminopeptidase N"”.
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Exploring the Physiological Role of Vibrio fischeri PepN
<p>The primary contributor to Vibrio fischeri aminopeptidase activity is aminopeptidase N, PepN. Colonization assays revealed the pepN mutant strain to be deficient at forming dense aggregates and populating the host’s light organ compared to wildtype within the first 12 hours of colonization; …
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Impact of Dietary Proteins on Growth Performance, Intestinal Morphology, and mRNA Abundance in Weanling Pigs
… intestinal segment interactions (P < 0.05) for aminopeptidase A and aminopeptidase N. Aminopeptidase A was evenly distributed along the small intestine in the Peptiva® group, but decreased dramatically in the ileum in other groups. Aminopeptidase N increased from the proximal to the distal …
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Receptor Binding Domains and Coronavirus Adaptation and Evolution
… the S-protein of HCoV-229E in complex with human aminopeptidase N (hAPN) and ii) the carbohydrate binding domain (CBD) of the S-protein of HCoV-OC43 in complex with 9-O-Acetyl-N-acetylneuraminic acid (Neu5,9Ac2). In addition, viral sequence analysis, binding studies, and comparative sequence and …
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Peptide Targeting of Platinum Anti-Cancer Drug and Synthesis of Water Soluble Monofunctional Pt(II) Complexes Useful for Biological Labeling
… specifically in solid tumors and has receptors aminopeptidase N (APN), also referred to as CD13 which binds specifically to NGR peptides. Luteinizing hormone-releasing hormone (LHRH), another targeting moiety, has been found to be more prevalent in tumor cells than normal cells and has …
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Effect of Corn Quality and Enzyme Supplementation on Broiler Performance, Gastrointestinal Enzyme Activity, Nutrient Retention, Intestinal Mucin, and Jejunal Gene Expression
… for determination of maltase, sucrase, and aminopeptidase N activities. Jejunal tissue on d 28 was also collected for total RNA isolation and a subsequent genome-wide microarray assay. On d 50, 54 birds per trt were processed to evaluate carcass yield. Interactions of ME and AZ were observed …
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Platinum-NGR A Peptide Targeting Conjugate Of Cisplatin: Design, Synthesis, And Efficacy In Breast Cancer Cells
… cells as a result of their interaction with aminopeptidase N (APN), or CD13, receptors. Fmoc solid phase chemistry was employed via a peptide synthesizer to produce mPeg-CNGRC-mal free peptide that was then cyclized and conjugated to activated cisplatin, producing a conjugated …
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Distribution and Relative Abundance of Nutrient Transporter mRNA in the Gastrointestinal Tract of Black Bears
… (NBAT, bo,+AT), and a digestive enzyme, aminopeptidase N (APN), in the intestinal tract of black bears were investigated. Ten bears were used for this study. For tissue collection, the intestine was removed from the animal and divided into five sections. Each collected section was opened …
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Developmental Regulation of the Expression of Nutrient Transporter and BrushBorder Membrane Hydrolase Genes in the Small Intestine of Piglets
… MGA), three peptide hydrolases (aminopeptidase A, APA, aminopeptidase N, APN, and dipeptidyl peptidase IV, DPP IV), two sugar transporters (Na+-dependent glucose transporter 1, SGLT1, and facilitated glucose transporter 5, GLUT5), a peptide transporter (H+-dependent peptide …
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BEES AND WASPS IN A CHANGING ENVIRONMENT: MULTIPLE RESPONSES TO ANTHROPISED LANDSCAPES
… green urban areas showed reduced activity of Aminopeptidase N, a proteolytic enzyme. Finally, hotter urban areas reduced the abundance of some bee viruses in A. plumipes and O. cornuta, while fragmentation increased the presence of the protozoan Apicystis bombi in A. plumipes, O. cornuta, and …
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
… domain of PEDV. Since Vero cells do not possess aminopeptidase N (APN) which is a known cellular receptor for alphacoronaviruses, PEDV may bind to a cellular receptor other than APN.</p> <p>Overall, the present research contributes to the understanding the ontogeny of antibody response to PEDV …
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Early nutrition affects intestinal development and immune response in the neonatal piglet
… and activity was higher at d14 compared to d7. Aminopeptidase N (APN) was measured in both jejunum and ileum, and Dipeptidylpeptidase IV (DPPIV) was measured in jejunum and ileum, as well as serum. In the jejunum, both day (p=0.0023) and diet (p=0.0003) were significant, with d7 piglets having …