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Showing 1 to 20 of 56 for “"Aminopeptidase"”.
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Klonierung und Charakterisierung der humanen Puromycin-sensitiven Aminopeptidase
… erwartete Richtung. Mit der Puromycin-sensitiven Aminopeptidase war ein Gen aus der Familie der Metallopeptidasen gefunden worden, eine Exopeptidase mit einem Zink-Ion im katalytischen Zentrum. Proteinchemisch schon vor einigen Jahren isoliert, war über die PSA (Puromycin-sensitive Aminopeptidase) …
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Charakterisierung der Eaf 1-Funktion für die Biogenese der Aminopeptidase 1
… cerevisiae wird die Leucin-Exopeptidase Aminopeptidase 1 (Ape1) als Vorläuferform im Zytoplasma synthetisiert, zu Homododecameren oligomerisiert, anschließend über den Cvt-Transportweg in die Vakuole transportiert und dort prozessiert. Die Isolierung und Charakterisierung zweier Mutanten …
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Identification of a new factor essential for vacuolar aminopeptidase I activity.
Die vakuoläre Aminopeptidase I der Bäckerhefe, Ape1p, wird durch konstitutive Autophagozytose aus dem Zytoplasma in die Vakuole transportiert. Ape1p wird als Proform mit einer N-terminalen Sortierungssequenz synthetisiert, die in der Vakuole durch Endopeptidasen abgespalten wird. In der enzymatisch …
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Purification and Characterization of Native and Recombinant Dipeptidyl Aminopeptidase 1 of Plasmodium falciparum
Plasmodium falciparum dipeptidyl aminopeptidase 1 (DPAP1) contributes to the degradation of hemoglobin by releasing dipeptides from globin oligopeptides in the food vacuole. The lack of success at DPAP1 gene disruption suggests that this exopeptidase is important for efficient growth during the …
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Isolierung, Identifizierung und funktionelle Charakterisierung der Metallo-Aminopeptidase CaApe2 — Ein experimenteller Beitrag zur Beurteilung des kariogenen Potentials von Candida albicans
… neutrale Arginin/Alanin/Leucin-spaltende Metallo-Aminopeptidase (CaApe2) zu, die durch den ORF CaO19.5197 (GenBank RefSeq XM 705313) kodiert wird. Mithilfe der Proteinanalytik wurde Serin-88 als N-terminale Aminosäure ermittelt. Die Aminosäuren 88 bis 954 des hypothetischen Genprodukts ergeben …
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The Development of Certain Enzymes and Iso-Enzymes During Normal Pregnancy
… serum activity of carboxypeptidase, leucine aminopeptidase, alanine aminopeptidase, cystine aminopeptidase, γ-glutamyl transpeptidase, alkaline phosphatase, glucose-6-phosphatase, 5-nucleotidase, n-acetyl-β-glucosaminidase, n-acetyl-β-galactosaminidase and β-glucuronidase, have been found to …
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Isolation and characterization of Saccharomyces cerevisiae mutants for vacuolar import and autophagocytosis
The yeast vacuolar protein aminopeptidase 1 (Apelp) is synthesised as a cytosolic procursor that is transported to the vacuole via the cytoplasm to vacuole trnasport (Cvt) pathway. The cytosolic protein is enclosed in a double-membrane vesicle, which is transported to and fuses with the vacuole …
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Exploring the Physiological Role of Vibrio fischeri PepN
<p>The primary contributor to Vibrio fischeri aminopeptidase activity is aminopeptidase N, PepN. Colonization assays revealed the pepN mutant strain to be deficient at forming dense aggregates and populating the host’s light organ compared to wildtype within the first 12 hours of colonization; …
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Control of the release of digestive enzymes in the cricket Gryllus bimaculatus and the fall armyworm, Spodoptera frugiperda
… enzyme release was investigated. More trypsin, aminopeptidase and amylase are secreted in the caecum of fed crickets than in unfed crickets, but basal levels of certain enzymes are released continuously even in unfed animals. A variable ratio of nutrients in ingested food leads to a different …
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Impact of Dietary Proteins on Growth Performance, Intestinal Morphology, and mRNA Abundance in Weanling Pigs
… intestinal segment interactions (P < 0.05) for aminopeptidase A and aminopeptidase N. Aminopeptidase A was evenly distributed along the small intestine in the Peptiva® group, but decreased dramatically in the ileum in other groups. Aminopeptidase N increased from the proximal to the distal …
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Aktivierung und Inaktivierung des Cry8C-Toxins von Bacillus thuringiensis japonensis Stamm Buibui im Darmsystem von Engerlingen (Scarabaeidae)
… 3 trypsin- und elastaseartige Serinproteasen, 1 Aminopeptidase und 2 weitere Metalloproteasen charakterisiert. Hinzu kommt eine membranständige Aminopeptidase. Im Vergleich zu weiteren Scarabaeiden variieren die Anzahl, die Molekularmassen und die Aktivitäten einzelner Proteasen, aber einen …
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Biochemical Characterization of Two Aminopeptidases Involved in Hemoglobin Catabolism in the Food Vacuole of Plasmodium falciparum
… a majority of the host hemoglobin. Two metalloaminopeptidases, PfAPP and PfA-M1, have been previously localized to the food vacuole (in addition to distinct secondary locations for each), implicating them in the final stages of hemoglobin catabolism. Prior genetic work has determined these …
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The proteolytic activity of yoghurt and probiotic bacteria for the improved viability of probiotic bacteria in fermented milk products
… at the extracellular and intracellular levels. Aminopeptidase activities were measured using chromogenic substrates (p-nitroanilide derivatives of Lanomers of leucine, lysine, alanine, proline, arginine, and methionine). Dipeptidase activities were measured using dipeptides including Ala-Met, …
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The isolation, identification and detection of Clostridium Difficile
… for various Clostridium spp., the use of prolyl aminopeptidase, p-galactosidase, leucine aminopeptidase, indole production and acid phosphatase allowed the rapid identification of 96.4% of strains of Cl.difficile (within 30 minutes). The remaining isolates required an additional test, whilst no …
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A Comparative Study of the Substrate Specificities of Peptidases A, B, and N From Salmonella Typhimurium
… properties. PepB is a broad specificity aminopeptidase with a unique ability to remove Asp residues and a very efficient ability to remove Glu residues from the N-termini of peptides in than PepA and PepN. PepA, on the other hand, removes Pro residues, a function lacking in PepB and PepN. …
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