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Showing 1 to 20 of 96 for “"Aminobutyric acid"”.

  1. Synthesis and evaluation of β-fluoro-γ-aminobutyric acid enantiomers

    Deniau, GildasUniversity of St Andrews2007

    … from phenylalanine indicated that amino acids are practical starting materials for the preparation of β-fluoroamines. This methodology is applied to L-lysine to generate (2R)-fluorohexane-1,6-diamine. The formation of a diamine of potential interest for catalysis is also observed in this …

    st-andrews Repository record

  2. Role of gamma-aminobutyric acid (GABA) in hypothalamic nuclear development

    McClellan, Kristy Michelle, author, Tobet, Stuart A., advisorColorado State University. Libraries2008

    The hypothalamus is involved in energy balance, appetite regulation, stress and anxiety, reproduction including sex behavior, and aggression. It is divided into cell groups based on cell staining, functional similarities and projections. This dissertation looks at the development of three of these …

    colostate Repository record

  3. The synthesis and pharmacology of gamma-aminobutyric acid receptor mimetics

    McDonald, Jane Anne MargaretCity of London Polytechnic1981

    Gamma-aminobutyric acid (GABA) has been shown to be an important inhibitory neurotransmitter in mammalian central nervous system (CNS). GABA receptors have been previously characterized in mammalian brain using 3H-GABA itself, a potent GABA agonist, 3H-muscimol, and the GABA antagonist, …

    london-metro Repository record

  4. The synthesis and biochemical and pharmacological evaluation of gamma-aminobutyric acid antagonists

    McLaughlin, Neil JamesCity of London Polytechnic1981

    Y-Aminobutyrio acid has been shown to be a major inhibitory neurotransmitter in the central nervous system (CNS). This study is concemed with the examination of a number of GABA antagonists in two in vitro assay systems. A series of cage-structured compounds including bicyolic phosphate esters …

    london-metro Repository record

  5. Protein modulators of voltage-gated Na+channels and γ-aminobutyric acid type a receptors

    Gonzalez-Prada Felices, Jose EnriqueUniversity of Cambridge2025

    [Restricted]

    cambridge Repository record

  6. The role of Gamma-aminobutyric acid and Hydrogen peroxide in cell death in grape berry development

    Gowder Shekharappa, Chethana2022

    … berries. Another metabolite of interest is Gamma-aminobutyric acid (GABA) which might have a role in cell death in berries because the concentration of H2O2 and GABA in cells tends to increase under stress. Chapter 1 analyses the literature on H2O2, and GABA, a four-carbon non-protein amino acid …

    adelaide Repository record

  7. Temporal Changes in the Levels of Gamma-Aminobutyric Acid in the Brain of the Cockroach, Leucophaea Maderae

    Newton, Jonathan

    … clock, and it has been shown that gamma-aminobutyric acid (GABA) plays an important role in the vertebrate circadian system. The importance of GABA in the vertebrate SCN and its presence in the brain of the cockroach made the inhibitory neurotransmitter GABA a prime candidate for related …

    wku-diss Repository record

  8. Glutamic Acid Decarboxylase and the Gamma-Aminobutyric Acid Pathway in the Supraesophageal Ganglion of the Honeybee, Apis Mellifera (Hymenoptera, Apidae)

    Fox, Philip MichaelUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-11T18:05:31Z (GMT). No. of bitstreams: 1 7105098.pdf: 3708700 bytes, checksum: fe7964e6cd4b948a191c97559688f42f (MD5) Previous issue date: 1970

    uiuc Repository record

  9. Evaluating the impact of heat stress and altered glycemic state on plasma ɣ-Aminobutyric Acid (GABA) in lactating Holstein cows

    Arneson, Alicia GestVirginia Tech2021

    … in lactating dairy cows. We hypothesized that γ-aminobutyric acid (GABA) participates in the regulation of this altered glycemic state as it is produced by the pancreatic beta cells and has a stimulatory effect on pancreatic secretion of insulin. Multiparous lactating Holstein cows (n=6; …

    vt Repository record

  10. Alcohol alters the expression of Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptors (SNAREs) and spontaneous γ-Aminobutyric Acid (GABA) release...

    Varodayan, Florence Prabha2013

    … We found that alcohol increased gamma-aminobutyric acid (GABA) release via HSF1, but had no effect on glutamatergic synaptic vesicle fusion. Collectively, these data indicate that alcohol induction of HSF1 transcriptional activity triggers a specific coordinated adaptation in GABAergic …

    columbia-diss Repository record

  11. Implementation of Hadamard Encoding and Reconstruction of MEGA-Edited Spectroscopy (HERMES) for quantification of ɣ-aminobutyric acid (GABA) and glutathione (GSH)

    Rimbault, DanielDivision of Biomedical Engineering2020

    … aimed to accelerate and improve accuracy of ɣ-aminobutyric acid (GABA) and glutathione (GSH) quantification. These metabolites, present at low concentrations in the brain, are challenging to detect using MR spectroscopy due to the fact that their resonance frequencies overlap with those of …

    cape-town Repository record

  12. The preparation of racemic and optically active beta-amino-acids and their utilisation in peptide formation.

    Mtetwa, EliRobert Gordon's Institute of Technology1978

    B-Amino acids are being isolated from biologically active peptide antibiotics with increasing frequency nowadays. Recognition of the importance of these amino acids, has led to their incorporation into synthetic peptide analogues and into polymers. The main part of this thesis reports the …

    rgu Repository record

  13. The biosynthesis of virginiamycin S₁

    Molinero, Anthony A.Virginia Polytechnic Institute and State University1982

    … incorporated into the respective amino acid components in the antibiotic. N-Methyl-L-phenylalanine was shown to arise from L-(U-14C)-phenylalanine and L-(methyl-14C)-methionine. L-(U-14C)-Phenylalanine was also efficiently incorporated into L-phenylglycine. The origin of the remaining …

    vt Repository record

  14. A biochemical investigation into aspects of the neuro active amino acid receptor complexes in the insect nervous system

    Baines, PeterCity of London Polytechnic1986

    … undertaken to study the glutamate (L-glu) and aminobutyric acid (GABA) receptors in the central nervous system (CNS) of the American cockroach, Periplaneta americana. The aim was to provide a simple, quick and cost effective method of screening new chemical entities as potential insecticides …

    london-metro Repository record

  15. Nutrition in relation to coremia and spore production in Penicillium clavigerum

    Tinnell, Wayne HoustonVirginia Polytechnic Institute1967

    … containing glucose, mineral salts; and the amino acid L-proline was developed for the propagation of Penicillium clavigerum. Certain modifications of this medium produce dramatic differences in colonial morphology. Coremia are produced only if certain dipeptides are added to the medium. The …

    vt Repository record

  16. ΣΥΜΒΟΛΗ ΣΤΗΝ ΕΡΜΗΝΕΙΑ ΤΗΣ ΝΕΥΡΟΓΕΝΟΥΣ ΡΥΘΜΙΣΗΣ ΤΗΣ ΕΓΚΕΦΑΛΙΚΗΣ ΚΥΚΛΟΦΟΡΙΑΣ

    Angelopoulos, Elias, Αγγελόπουλος, ΗλίαςNational and Kapodistrian University of Athens1986

    TO TEST THE HYPOTHESIZED ROLE OF GAMMA-AMINOBUTYRIC ACID (GABA) ON THE CEREBRAL CIRCULATION, WE USED A PRESSURE MICRO-INJECTION SYSTEM TO SIMULTANEOUSLY ADMINISTER VARIOUS CONCENTRATIONS OF GABA AND MEASURE THE TISSUE PO22 USING AN ADJACENT PO2 MICROELECTRODE. GABA INJECTED DIRECTLY INTO THE …

    greece Repository record

  17. Understanding correlations between secondary relaxations and thermal behaviour of biologically relevant molecules

    Owusu-Ware, SamuelUniversity of Greenwich2013

    … scrutiny. Experiments on crystalline butyric acids, γ-aminobutyric acid (GABA), DL-α-aminobutyric acid (AABA) and DL-β-aminobutyric acid (BABA), were undertaken in order to examine the influence of positional isomerism on molecular mobility and stability. These molecules differ in the …

    greenwich Repository record

  18. Detection and Imaging of Neurotransmitters in Rodent Brain Tissue Using FMP-10 and ZnO Nanoparticle Matrices with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

    Pusparajah, MathushaThe University of Western Ontario2024

    … to detect 17 neurochemicals, notably dopamine, γ-aminobutyric acid (GABA), serotonin, and norepinephrine. ZnO NP detects 9 neurochemicals, including glutamate and glutamine, which are undetectable by FMP-10. We applied both matrices to investigate neurochemical changes in male and female …

    uwo Repository record

  19. Modulation of GABAergic transmission in the cerebellar stellate cell network by neurotransmitter spillover and synaptic cross talk

    Astori, SimoneUniversität Heidelberg

    … probability of the inhibitory neurotransmitter ?-Aminobutyric acid (GABA). Analysis of synaptic parameters combined with the application of pharmacological tools indicated the involvement of metabotropic GABAB receptors and ionotropic L-?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid …

    heid-diss Repository record

  20. CHEMICAL INDUCTION OF SETTLEMENT IN LARVAE OF THE EASTERN OYSTER <italic>CRASSOSTREA VIRGINICA </italic> (GMELIN)

    Grant, Melissa2009

    … of 9.6 (&plusmn;0.1). The compounds &gamma;-aminobutyric acid and acetylcholine chloride, both at 10<super>-4</super>M, did not significantly increase the percentage of larvae exhibiting settlement behavior. As compared with the control, a significant increase in settlement behavior was …

    maryland Repository record

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