Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Amino acid availability"”.
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Evaluation of Methods for Improving Phytate Phosphorus Utilization in Poultry and Swine
… thereby indicating that phytase did not increase amino acid availability in several phytate-containing ingredients as assessed by a PER assay.
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Discovering regulators of the amino acid sensing pathway of mTORC1
… anabolic and catabolic processes. A key input is amino acids, which function to promote the translocation of mTORC1 to the lysosomal surface, its site of activation. Necessary for this recruitment are the Rag GTPases and several distinct factors that modulate their nucleotide state in response to …
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Regulation of postprandial protein metabolism after food ingestion and exercise
… resulted in a sustained release of dietary amino acids in circulation that coincided with prolonged postprandial elevations in intramuscular anabolic signaling and rates of muscle protein synthesis. In study 2, we demonstrated that production of labeled food proteins can be done in a …
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Regulation and roles of nutrient-dependent mitochondrial fusion
… shown that mitochondria undergo fusion during amino acid starvation-induced autophagy. This mitochondrial response has been proposed to be regulated by MTORC1, a key regulator of nutrient-sensing signalling pathway. However, the mechanism linking MTORC1 and nutrient sensing to mitochondrial …
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The modification of nutritional and functional properties of chickpea (Cicer arietinum) by germination.
… as germination time increased. Essential amino acid availability did not change after 24 hr of germination, but small decreases were observed after 48 hr. Protein and starch were studied separately to determine their influence on the observed modifications. No significant changes were …
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Assessing Availability and Utilization of Essential Amino Acids in Dairy Cattle Using Stable Isotope Based Approach
Determining the AA availability and metabolism in ruminant is a big challenge due to the rumen fermentation and complicated post absorption utilization. Current techniques used for direct determination of AA absorption and metabolism are laborious and expensive with large variation. The objectives …
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INTERACTIVE EFFECT OF DIETARY FIBRE AND IMMUNE CHALLENGE ON THREONINE REQUIREMENT AND INTESTINAL BARRIER FUNCTION IN GROWING PIGS
… system stimulation (ISS) are thought to limit amino acid availability for protein deposition (PD) and growth in pigs. Fibre and threonine (Thr) may also play an important role in intestinal barrier function. Therefore, this thesis evaluated the independent and combined effects of high DF and …
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The regulation and function of Forkhead box O transcription factors FOXO1 and FOXO3 in T and iNKT lymphocytes
… FOXO1 is not regulated by glucose or amino acid availability in CTL, which are essential regulators of CTL growth, proliferation and effector function. <br/><br/>Using FOXO1<sup>GFPflx/GFPflx</sup> Granzyme B cre mice, we investigated whether deletion of FOXO1 expression in activated T …
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Exploring the Plasmodium falciparum Transcriptome Using Hypergeometric Analysis of Time Series (HATS)
… protein production in response to reduced amino acid availability from degraded hemoglobin. We observed that a copy number increase in pfmdr1 resulted in increases in glycerophospholipid metabolism and up-regulation of a number of ABC transporters. Finally, when comparing artemisinin …
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Non-canonical functions of leucyl-tRNA synthetase: Mechanism of cell growth and skeletal myogenesis
… of environmental and cellular cues, including amino acid sufficiency, which is a prerequisite for mTORC1 activation under all conditions. The mechanism of how cellular amino acids are sensed has been a long-standing question. Recent discoveries of several direct amino acid sensors have begun to …