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Showing 1 to 9 of 9 for “"Ames test"”.
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Mutagenicity of root canal sealer RSA Roekoseal Automix in the Ames test
… sealers, RSA Roekoseal Automix and AHPIus, were tested in the bacterial gene mutation assay (Ames test). Both materials were tested immediately after mixing and after setting 24 h. The Salmonella typhimurium tester strains TA98 and TA 100 were used to detect the induction of frame shift mutations …
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Charakterisierung von genotoxischen organischen Luftstaubextrakten
… Verteilungsmuster der biologischen Aktivität im Ames-Test. Für die Extrakte von atmosphärischen Luftstäuben zeigte die Fraktion der stark sauren Verbindungen die höchste genotoxische Aktivität. Die Kfz- bzw. Kokereiabgaspartikelextrakte wiesen die höchste Genotoxizität in der Fraktion der …
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Optimierung der Expressionsstärke von fremdstoffmetabolisierenden Enzymen in Bakterien und permanenten Zellkulturen für toxikologische Untersuchungen
… Mutagenität mittels bakterieller in-vitro Testsysteme ist die heterologe Expression der fremdstoffmetabolisierenden Enzyme direkt in den Indikatorzellen notwendig. S. typhimurium exprimieren selbst keine SULT, und externe Metabolisierungssysteme sind problematisch, weil die negativ …
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Toxicology and herb-drug interaction of selected anti-hypertension plants used by lay persons in Northern KwaZulu-Natal (South Africa)
… in the current study have been previously tested for any toxicity. Aqueous and organic (1:1 dichloromethane-methanol) extracts were prepared. The toxicity was evaluated using three assays [the brine shrimp lethality assay (BSLA), Ames test and MTT assay (human hepatocarcinoma cell line …
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BIOTRANSFORMATION AND MUTAGENICITY OF BENZIDINE
… was mutagenic after microsomal activation in the Ames test, the fluctuation test using Ames tester strain TA98, and the inductest-(beta)-galactosidase assay. The transformation products were mutagenic without requiring prior microsomal activation. The inductest-(beta)-galactosidase assay (Elespuru …
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Computational Methods in Support of Chemical Risk Assessment
… of chemicals and to assess chemicals for which testing is not routinely required. The application of TTC relies heavily on computational (in silico) methods. In silico tools are computer implemented models that, based on commonalities in the toxicity of “similar” chemical structures, may predict …
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Deep Eutectic Solvents Synthesis, Characterization and Applications in Pretreatment of Lignocellulosic Biomass
… individual components were evaluated using the Ames test and LDH, and MTT assays. A synergetic effect was observed because the toxicity of DESs was higher than their individual components. Therefore careful use of the term nontoxic must be considered. The genotoxicity and cytotoxicity of the …
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Charakterisierung von Sulfotransferasen im Gastrointestinaltrakt von Mensch und Ratte und Aktivierung von Promutagenen in V79-Zellen, die eine intestinale Form (1B1) des Menschen und der Ratte exprimieren
Die Ausstattung der gastrointestinalen Mukosa des Menschen und der Ratte mit Sulfotransferasen wurde mit Hilfe von Immunodetektion und Enzymaktivitätsmessungen untersucht. In Proben aus Colon und Rektum von 39 Personen wurden die Formen h1A1, h1A3 und h1B1 identifiziert, wobei in einer weiteren …
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ΠΑΡΑΚΟΛΟΥΘΗΣΗ ΤΗΣ ΑΤΜΟΣΦΑΙΡΙΚΗΣ ΡΥΠΑΝΣΗΣ ΤΗΣ ΕΥΡΥΤΕΡΗΣ ΠΕΡΙΟΧΗΣ ΑΘΗΝΩΝ ΑΠΟ ΠΟΛΥΚΥΚΛΙΚΟΥΣ ΑΡΩΜΑΤΙΚΟΥΣ ΥΔΡΟΓΟΝΑΝΘΡΑΚΕΣ
IN THE THESIS THE CONCENTRATIONS OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) IN THE ATHENS ATMOSPHERE WERE STUDIED. NINE DIFFERENT PAH WERE IDENTIFIED AND QUANTIFIED. THE RESULTS OF THESE DETERMINATIONS INDICATE THAT: (I) THE PAH CONCENTRATIONS WERE HIGHER IN THE CENTRAL AREA OF ATHENS CITY THAN IN …