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Showing 1 to 1 of 1 for “"Alzheimer's diease"”.
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Small Molecule Binding to Disordered Proteins
… peptide (Aβ), whose aggregation is a hallmark of Alzheimer's disease. In Chapter 3, I employ metadynamic metainference restrained with NMR data to identify the structural origins Aβ42's lower solubility with respect to Aβ40, and show how this structural insight can be applied towards novel …