Global ETD Search
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Showing 1 to 5 of 5 for “"Alt a 1"”.
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Characterizing the Innate Immune Response of Human Airway Cells to the Unique Fungal Allergen Alt a 1
… sensitization to fungi including Aspergillus, Alternaria, Cladosporium, and Penicillium. This project has been focused on studying the innate immunomodulatory activities of the major allergen Alt a 1, from the ubiquitous airborne fungus, Alternaria alternata. In several studies, 90-100% of …
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The Role of Alternaria and its Major Allergen, Alt a 1, in the Pathogenesis of Allergic Airway Disorders
… exposure to the ubiqutious airborne fungus, Alternaria alternata, has long been implicated in the development and exacerbation of human allergy and asthma. Alt a 1 was identified previously by several groups as the major allergen secreted by A. alternata, due to its IgE-specific reactivity …
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Innate Immune Responses in the Alternaria-Dendritic Cell Interaction
Exposure to spores and hyphae of Alternaria alternata, an airborne ubiquitous fungus, is clinically associated with allergic airway disorders including allergic rhinitis, asthma, and chronic rhinosinusitis. Dendritic cells are known as the type of antigen presenting cells most often associated with …
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Analysis of the Allergenic Potential of the Ubiquitous Airborne Fungus Alternaria Using Bioinformatics
… airborne fungi one of the most common is <i>Alternaria alternata</i>. From a clinical perspective Alternaria has long been associated with IgE-mediated, histamine-dependent mold allergy, allergic rhinitis, chronic rhinosinusitis (CRS) and asthma. Recently it has been proven that an abnormal …
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Molecular dissection of Alternaria brassicicola pathogenesis mechanisms
Alternaria brassicicola is a necrotrophic fungal pathogen that causes black spot disease on cruciferous plants including economically important Brassica species and the model plant Arabidopsis thaliana. The purpose of this dissertation was to gain a better understanding of the pathogenesis …