Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"Alphavbeta3"”.
-
INTEGRIN ALPHAVBETA3 AS THERAPEUTIC TARGET AND IMAGING BIOMARKER FOR VASCULAR ENDOTHELIAL CELLS AND CANCER EPITHELIAL CELLS
Integrins are heterodimeric transmembrane proteins belonging to a family of cell adhesion receptors evolutionary old and that play pivotal roles in physiological and pathological processes, such as neo-angiogenesis and cancer spreading. Integrins are composed by an extracellular domain, a single …
-
Evaluation of new succinimide-based small molecules as alphavbeta3 integrin antagonists: from design to preliminary biological testing
Integrins are a family of cell surface protein receptors consisting of two subunits, called α and β, involved in several biological processes, including regulation of signalling between cells and other cells or ECM. Integrins are overexpressed in diseases, first of all cancer. Being able to bind …