Global ETD Search
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Showing 1 to 1 of 1 for “"Alpha-synucelin aggregation"”.
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Mechanistic modeling of alpha-synuclein aggregation and brain pharmacokinetics for drug development in neurodegeneration
… the work focuses on the mathematical modeling of alpha-synuclein (aSyn) aggregation dynamics under in vitro conditions—a molecular process relevant to Parkinson’s disease (PD) and other synucleinopathies. Building on in vitro aggregation studies and chemical kinetic models, we develop a …