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Showing 1 to 18 of 18 for “"Alpha-linolenic acid"”.
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FATTY ACIDS IN PHYSIOLOGY AND PATHOLOGY: FOCUS ON ALPHA-LINOLENIC ACID (ALA) AND PUFAS
… roles of polyunsaturated fatty acids (PUFAs), focusing on alpha-linolenic acid (ALA), and linoleic acid (LA), within a broad range of human biological processes. PUFAs are essential nutrients involved in modulating cell membrane fluidity, intracellular signaling, and gene …
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The Effect of Dietary Alpha - Linolenic Acid on Apparent Risk Factors of Cardiovascular Disease
… age (22 to 53 years) were fed a diet rich in α-linolenic acid (18:3 ω 3) for four weeks. Arterial blood pressure and body weight were recorded each week. Plasma 6-keto-prostaglandin F<sub>1α</sub> (6-keto- PGF<sub>1α</sub> ), thromboxane B<sub>2</sub> (TXB<sub>2</sub>), total cholesterol, …
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Studies on the Possible Regulatory Function of Dietary Alpha-Linolenic Acid in Prostaglandin Synthesis by Immunocompetent Cells
Alpha-linolenate (18:3(omega)3) and its elongated, desaturated metabolites are known to predominate in certain tissues. The role of essential fatty acid (EFA), and therefore of PGs, in cell-mediated immunity has increasingly become of interest. Prostaglandins have been implicated in many areas of …
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Effects of dietary alpha linolenic acid on biosynthesis of N-3 long chain polyunsaturated fatty acids in animals.
Omega-3 (n-3) long chain polyunsaturated fatty acids (LCPUFA), particularly eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3), are important for normal health as well as growth and brain development in humans. These fatty acids can be consumed in the diet directly, or …
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SEX DIFFERENCES IN THE RELATIONSHIP OF POLYUNSATURATED FATTY ACIDS AND NONINVASIVE IMAGING MEASURES OF SUBCLINICAL CARDIOVASCULAR DISEASE
… the cardiovascular benefit of the omega-3 fatty acid alpha-linolenic acid (ALA).
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Formulation and Physical, Chemical and Sensory Analysis of a Novel Flaxseed-enriched Milk-based Beverage to Deliver Omega-3 Fatty Acids
… beverages is occurring, and omega-3 fatty acids (FA) are one of the most commonly sought ingredients to fortify such beverages. Omega-3 FA produce beneficial health effects, likely due to their anti-inflammatory properties. The majority of current omega-3 FA-fortified products include …
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Hepatic microsomal and peroxisomal docosahexaenoate biosynthesis during piglet development
… on the biosynthetic pathway for docosahexaenoic acid (DHA) from [Alpha]-linolenic acid (ALA) were investigated. Microsomes and peroxisomes were prepared from livers of fetal and neonatal piglets by a combination of differential and gradient layer centrifugation. Microsomes, peroxisomes and …
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Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
Regulation of polyunsaturated fatty acid (PUFA) biosynthesis in proliferating and NGF-differentiated PC12 pheochromocytoma cells deficient in n-3 docosahexaenoic acid (DHA, 22:6n- 3) was studied. A dose- and time dependent increase in eicosapentaenoic acid (EPA, 20:5n-3), docosapentaenoic acid …
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Feeding Female Growing Rats Different Sources of Omega-3 Polyunsaturated Fatty Acids Affects Lung Fatty Acid Composition and Gene Expression
… of lung damage. Omega-3 polyunsaturated fatty acids (n-3 PUFAs), found in different dietary sources, regulate the expression of various genes involved in eicosanoid production and oxidative stability.;Objective: to determine whether providing different sources of n-3 PUFAs will affect the fatty …
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Local effects of Linoorbitides and enterolactone On intestinal epithelial functions
… known bioactives including fibers, lignans, alpha-linolenic acid, and linoorbitides (LOBs) are believed to impart those pharmacological activities. Previous studies have focused on the ability of flaxseed bioactives to provide their pharmacological action in the systemic circulation. However, …
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INVESTIGATION OF THE CARDIOPROTECTIVE AND HYPOTRIGLYCERIDEMIC POTENTIAL OF ECHIUM OIL AS A BOTANICAL SOURCE OF LONG CHAIN N-3 FATTY ACIDS
… of fish oil (FO) and n-3 polyunsaturated fatty acid (PUFA) supplements has been shown to be cardioprotective and result in several health benefits, including reduced plasma triglyceride (TG) concentration, inflammation, endothelial cell activation, and atherosclerosis. FO contains …
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Effects of low linolenic soy oil on pre-malignant human mammary epithelial cell progression
… techniques, plant breeders have developed a low linolenic soybean with 83.36% less alpha-linolenic acid (ALA; omega-3) than conventional soybean. A number of studies have demonstrated that the influence of dietary fats on cancer depends on the quantity as well as the type of lipids and diets with …
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Immunomodulation by dietary lipids: soybean oil, menhaden fish oil, chicken fat, and hydrogenated soybean oil in Japanese quail (Coturnix coturnix japonica) and Bobwhite quail (Colinus virginianus)
… The SBO diet, in which 66% of the total fatty acids were polyunsaturated fatty acids (PUFA), was rich in linoleic acid (LA 18:2 n-6), alpha-linolenic acid (ALA 18:3 n-3) and low in saturated fatty acid (SFA). The FO diet which contained about 50% PUFA, had only 40% n-6 fatty acids and 8% n-3 …
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In vitro screening of commercial sorghum hybrids and omega-3 supplementation in Holstein steers
… hours. Cumulative gas production, volatile fatty acids concentrations from in vitro cultures, and in vitro dry matter disappearance were measured and used to assess how well microbes digested each grain. In situ dry matter disappearance (ISDMD) was measured for ground and RE processed grain to …
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Fatty acid regulation of adhesion molecule expression in human vascular cells.
… The consumption of n-3 polyunsaturated fatty acids (PUFA) from fish and fish oil have been shown to play an important role in the amelioration and prevention of cardiovascular disease and a number of inflammatory disorders. Similarly, conjugated linoleic acids (CLAs) from dairy products and …
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Treatment of Hypertriglyceridemia with Omega-3 Fatty Acids: A Systematic Review
… addressing the efficacy of long-chain ω-3 fatty acids as a secondary prevention agent of hypertriglyceridemia, and 2) make recommendations for clinical practice.</p> <p>Data Sources: All RCTs identified from several databases from 1993-2003 were reviewed by two independent reviewers who extracted …
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Production and health responses of laying hens and growing broilers to dietary omega-3 fatty acid supplementation
<p>Omega-3 fatty acids, specifically alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are known for possessing anti-inflammatory and bone modulating properties in murine and in vitro models. Health conscious consumers have created market demand for value-added …
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PROSTAGLANDIN E2 PATHWAY AS A TARGET TO PREVENT AND TREAT OVARIAN CANCER IN LAYING HENS
… that increased dietary intake of omega-3 fatty acids (OM-3FAs) reduces the incidence and growth of various cancers. Thus, increasing the consumption of OM-3FAs may be a nontoxic way to prevent or suppress ovarian cancer. Flaxseed is the richest vegetable source of omega-3 fatty acids which may …