"Alpha-Hydroxytropolone" · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"Alpha-Hydroxytropolone"”.

Discovery and Development of a Three-Component Oxidopyrylium Cycloaddition and Its Application Towards alpha-Hydroxytropolone Synthesis

D'Erasmo, Michael P.The Graduate School and University Center of The City University of New York2018

… endeavors made by our laboratory involving α-hydroxytropolones (αHTs).</p> <p>αHTs are a subclass of troponoid natural products that possess promising activity against a broad range of therapeutically significant targets. In order to gain access to these molecules, our laboratory utilizes an …

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Synthesis of Biologically Active Tropolones and Stereochemically Rich Compounds via Cross-Coupling Reactions

Agyemang, Nana BThe Graduate School and University Center of The City University of New York2023

… on the synthesis and biological evaluations of alpha-hydroxytropolones (alpha-HTs). These seven-membered aromatic rings have three contiguous oxygen atoms that chelates to metals, thus, biologically having the ability to bind dinuclear metalloenzymes and promoting inhibition. Synthetic routes to …

cuny-grad Repository record for Synthesis of Biologically Active Tropolones and Stereochemically Rich Compounds via Cross-Coupling Reactions (opens in a new tab)