Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 100 for “"Allogeneic"”.
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Donor lymphocyte infusion after allogeneic stem cell transplantation in children
… and bone marrow failure syndrome following allogeneic hematopoietic stem cell transplantation (allo HSCT). However, DLI is limited by the development of graft-versus-host disease (GVHD)and marrow aplasia, and the efficacy of DLIis not defined in children. So we evaluate DLI for last decade, …
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Macrophage regulation of the T cell allogeneic response during tumorigenesis
… affected the ability of NA cells to respond to allogeneic lymphocytes. Comparative reactivity was measured using normal cells and cells from mice in various stages of tumorigenesis. In MLR's using normal NA cells, recognition of allogeneic cells was dependent on addition of an optimal (2-3%) …
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ROLE OF THE GRAFT TISSUE IN THE IMMUNOBIOLOGY OF ALLOGENEIC TRANSPLANTATION.
ROLE OF THE GRAFT TISSUE IN THE IMMUNOBIOLOGY OF ALLOGENEIC TRANSPLANTATION.
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Subclonal Evolution of Chronic Lymphocytic Leukemia After Allogeneic T Cell Therapies
… evolution of chronic lymphocytic leukemia after allogeneic T-cell therapies</strong></p> <p>Haven Garber, MD</p> <p>Advisory Professor: Jeffrey Molldrem, MD</p> <p>Intratumoral genetic heterogeneity describes the molecular differences among subclones within a tumor and is a major barrier to …
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Allogeneic Double Negative T cell Therapy as a Novel Treatment for AML Patients
Allogeneic bone marrow transplantation (allo-BMT) is a potentially curative treatment for high-risk leukemia patients. However, a high disease relapse rate caused by residual disease and an associated toxicity such as graft-vs.-host disease (GvHD) remain as major issues that hamper recipients' …
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Exercise and activity patterns in cancer patients after recent allogeneic bone marrow transplatation
… activity levels and symptom severity following allogeneic BMT. The purposes of this dissertation was to perform an exploratory examination of the effectiveness of short-term clinician directed and self-directed exercise programs in recent allogeneic BMT/PBSCT patients using multi-dimensional …
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Exercise and activity patterns in cancer patients after recent allogeneic bone marrow transplatation
… activity levels and symptom severity following allogeneic BMT. The purposes of this dissertation was to perform an exploratory examination of the effectiveness of short-term clinician directed and self-directed exercise programs in recent allogeneic BMT/PBSCT patients using multi-dimensional …
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The diversity of participants in clinical trials involving allogeneic hematopoietic stem cell transplant recipients
… of participants in clinical trials involving allogeneic stem cell transplant recipients matched the diversity of the actual allogeneic recipient population overall. It is important that clinical trials study new therapies in a population that represents characteristics of the overall treatment …
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The Decelluarized Human Umbilical Vein (HUV) as an Allogeneic Scaffold for Vocal Fold Tissue Engineering
The human umbilical vein (HUV) has great potential for use as a biological tissue engineering scaffold. Thus far, it has been used as an extracellular matrix (ECM) scaffold for cardiovascular tissue engineering applications due to its many structural and biomechanical advantages. Since the HUV is …
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The Decelluarized Human Umbilical Vein (HUV) as an Allogeneic Scaffold for Vocal Fold Tissue Engineering
The human umbilical vein (HUV) has great potential for use as a biological tissue engineering scaffold. Thus far, it has been used as an extracellular matrix (ECM) scaffold for cardiovascular tissue engineering applications due to its many structural and biomechanical advantages. Since the HUV is …
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Tumor immune escape in allogeneic stem cell transplantation: Releasing the brake on graft-versus-tumor immunity
Contains fulltext : 101020.pdf (Publisher’s version ) (Open Access)
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Cord Blood-Derived Invariant Natural Killer T Cells as a Platform for Allogeneic Chimeric Antigen Receptor Cell Therapy
… to address these challenges is to create a safe allogeneic CAR cell product by using cells that do not cause graft versus host disease (GvHD). Invariant natural killer T (iNKT) cells are an ideal candidate as they are restricted to the monomorphic CD1d protein in contrast to HLA restricted αβ-T …
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Role of the Tcell genotype in the development of allogeneic responses after stem cell transplantation and cellular immunotherapy.
Contains fulltext : 19390.pdf (Publisher’s version ) (Open Access)
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Evaluation of allogeneic bone marrow-derived mesenchymal stem cells for use in equine joints: in vitro to preclinical evaluation
… with an average expansion time of 2-4 weeks. Allogeneic MSCs would offer multiple potential advantages over autologous MSCs use including timing of treatment, potential for characterization, and selection of donors for desired stem cell characteristics. The safety of allogeneic MSCs must be …
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Treatment Outcomes in Children with Very High Risk Acute Lymphoblastic Leukemia Intended to Treat with Allogeneic Hematopoietic Stem Cell Transplantation
… in spite of intensive chemotherapy. Recently, allogeneic hematopoietic stem cell transplantation (Allo-HSCT) was use to treat the patients with VHR ALL. We studied the clinical course and outcomes of children with VHR ALL intended treat with Allo-HSCT after chemotherapy. 16 children who were …
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Role of Lymphocyte Populations Following Allogeneic Haematopoietic Stem Cell Transplantation // Роля на лимфоцитните популации след алогенна трансплантация на хемопоетични стволови клетки
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is an established therapeutic approach for a range of malignant and benign haematological disorders. Despite significant advances in the field of transplantation medicine, this method remains associated with a number of complications – …
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Incidence rate of fluoroquinolone resistant gram-negative rod bacteremia among allogeneic hematopoietic cell transplant patients during an era of levofloxacin prophylaxis
… retrospective cohort study of adults undergoing allogeneic HCT between 2003 and 2012 at the Seattle Cancer Care Alliance (SCCA). Annual trends in the IRs of GNR bacteremia and FQ-resistant GNR bacteremia through 100 days post-transplant were assessed using Poisson regression. Cox proportional …
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Outcome of Severe Aplastic Anemia Treated with Immunosuppressive Therapy Compared with Bone Marrow Transplantation
… We compared response rates and survival after allogeneic bone marrow transplantation (BMT) or immunosuppressive treatment in severe aplastic anemia (SAA) and identified prognostic factors related with survival. METHODS: Medical data of SAA patients who treated with BMT or immunosuppressive …
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