Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 363 for “"Allergic"”.
-
Skin symptoms (allergic and non-allergic) predicting the development of allergic respiratory outcomes and asthma in bakers
… sensitization to allergens, resulting in adverse allergic respiratory outcomes including asthma in workers exposed to these agents. This appears to be reported more commonly for low molecular weight agents such as isocyanates and some cleaning agents. This study investigated whether skin symptoms, …
-
The homoeopathic treatment of seasonal allergic rhinitis
A dissertation submitted in partial compliance with the requirements for the Master's Diploma in Technology: Homoeopathy at Technikon Natal, Durban, South Africa, 1994.
-
Improving the management of allergic disease in adults.
… at baseline characteristics in demographics, allergic background and immunological biomarkers. Chapter 6 describes the progress of participants who were enrolled into the OPAL study and completed their Week 24 study visits. These participants have become tolerant of at least 300mg of peanut …
-
Peptide immunotherapy in models of allergic airways disease
… T cells are implicated in the pathogenesis of allergic disease. Peptide immunotherapy (PIT) involves therapeutic administration of short immunodominant peptides from within the protein allergen to which CD4+ T cell responses are directed. This approach can induce tolerance of allergen-reactive …
-
Sphingosine-1-phosphate in mast cell-mediated allergic responses
Mast cells play a critical role in both acute and chronic inflammation and mature in peripheral tissues from bone marrow-derived progenitors that circulate in the blood as immature precursors. Mast cell progenitors are likely to encounter the serum-borne bioactive sphingolipid metabolite, …
-
Role of Allergic Conjunctivitis in Inducing Corneal Transplant Rejection
… rate decreased to 0% in mice with ongoing allergic conjunctivitis. We set out to delineate the mechanisms by which allergic conjunctivitis abolishes immune privilege and results in corneal allograft rejection. Anterior chamber-associated immune deviation (ACAID) is initiated when foreign …
-
New Mediators and Novel Mechanisms in Allergic Airway Inflammation
… are major pathophysiological features of both allergic rhinitis and asthma. The mechanisms behind these are not fully understood. The aims of this thesis were to investigate if cytokines involved in the allergic response can induce airway hyperreactivity by affecting the airway smooth muscle …
-
Symptoms and aspects on eosinophil activity in allergic rhinitis
Allergic rhinitis is a major atopic disease. Even if much is known about the pathophysiology of this condition, and despite the fact that good treatments are available, there is a need for new treatment options, particularly for such aiming at new targets and reduced side effects. Recruitment and …
-
Factors affecting severity of injury in allergic renal disease
… infection induced relapse in certain cases of allergic renal disease. By demonstrating a mechanism of “protection" from the effect of circulating antibodies, these studies suggest that therapy directed towards blocking of available antigenic sites on the human glomerular basement membrane, may …
-
Stem Cell and Biological Interventions to treat Allergic Airway Disease
… a particular focus on airway inflammation and allergic pathogenesis. This was probed in a model of pathogen driven immunomodulation (B. pertussis), and two models of therapeutic intervention namely immunisation (attenuated B. pertussis, BPZE1) or using a candidate cell therapy approach …
-
Molecular mechanisms and complete antigen formation in allergic contact dermatitis
Allergic contact dermatitis (ACD) is a common T cell mediated skin disease. Small reactive organic molecules called haptens induce ACD. Haptens are not recognized by themselves, but need to bond to endogenous proteins in the skin, and processed further into complete antigens. Antigen specific T …
-
Severe allergic reactions at a tertiary paediatric service 2014 - 2016
… Memorial Children’s Hospital (RCWMCH) for severe allergic reactions between January 2014 and August 2016. Recruitment was by applying relevant ICD- 10 coding to the hospital’s clinical summary system of admissions and discharges, the pharmacy’s records of adrenaline autoinjector dispensing, and …
-
The temporal requirement of IL-4Rα signalling in allergic asthma and the role of IL-4Rα-responsive Regulatory T cells in restraining allergic airway inflammation
Allergic asthma is a chronic inflammatory airway disease driven predominantly by a TH2 immune response to environmental allergens. The asthma pathology is predominantly elicited by IL-4 and IL-13 signalling via IL-4Rα-signalling which is essential for driving TH2-type immunity to allergens. …
-
Gut bacteria, regulatory T cells and allergic sensitization in early childhood
… and, as consequence of this, development of allergic disorders. Thus, we examined if the infantile gut microbiota was related to the postnatal T cell development in vivo and if certain commensal gut bacteria were able to induce regulatory T cells (Tregs) in vitro. We also investigated if the …
-
The role of human CD23 in lgE homeostasis & allergic disease
… mIgM, to upregulate IgE synthesis and provoke allergic responses.<br/>To test this hypothesis, purified tonsil B cells were stimulated with IL-4 and anti-CD40 to induce class switching to IgE in vitro. mCD23 was up-regulated and sCD23 accumulated in the medium prior to IgE synthesis. IL-10 and …
-
Relationship between family histories and allergic disease with childhood atopic Dermatitis
… the relationship between parent's history of allergic disease and children's atopic dermatitis. Data from the 2011 Research on the Current Status of Atopic Disease with Elementary Schools and Kindergartens in Suwon were used for analysis. Among 20,052 persons agreeing to the survey 18,943 …
Page 1 of 19