Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Allergen Immunotherapy"”.
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Investigating the regulatory mechanisms of allergen-specific IgG4 production
… by an abnormal type 2 immune response, where allergen-specific IgE antibodies trigger granulocyte activation and allergic reactions. FA affects millions in Canada and is the leading cause of fatal anaphylaxis in Ontario, with no current cure available. Treatments like allergen immunotherapy …
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Epicutaneous Delivery of Allergens Using Dual Stimuli-Responsive Liposomes-Loaded Dissolving Microneedles
There has been a growing interest in allergen-specific epicutaneous immunotherapy (EPIT) as an alternative to oral immunotherapy due to safety concerns with oral approaches. A key challenge in EPIT is the effective delivery of macromolecular allergens across the stratum corneum (SC) without …
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Improving the management of allergic disease in adults.
… screened population of the Combining Peanut Oral Immunotherapy and Omalizumab in Adults with Peanut Allergy (the OPAL study) is described, looking at baseline characteristics in demographics, allergic background and immunological biomarkers. Chapter 6 describes the progress of participants who …
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Role of Toll-like receptors in airway inflammation
… and molecular changes occurring as a result of allergen-specific immunotherapy. In the first two studies, a distinct expression of TLRs was demonstrated in subsets of B and T lymphocytes isolated from human tonsils. The expression levels seemed to be affected by ongoing tonsillar infection. This …