Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"All or none"”.
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Latencies in paired-associate learning with normal and retarded children
Fifteen normal and 15 mentally retarded children of similar CA learned a paired-associate task within the frame-work of an all-or-none model learning in which the TLE was considered to be the pivot point of learning and in which only the associative "hook-up" phase of learning was studied. The …
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Long Term Plasticity Induced by Intracellular Tetanization in the Rat Auditory Cortex
… underlies the mechanisms of learning and memory, but it leads to runaway dynamics of synaptic weights and lacks mechanisms for synaptic competition. Heterosynaptic plasticity may solve these problems by complementing plasticity at synapses that were active during the induction, with …
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Is conscious perception a continuous or dichotomous phenomenon?
Is our conscious visual experience of the world characterised by events that appear suddenly or gradually in our awareness? This apparently simple question has proved difficult to resolve. Inspired by the global neuronal workspace theory, the dichotomous view (e.g. Sergent and Dehaene, 2004) …
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Molecular mechanisms of snare assembly and expulsion of intravesicular contents in cell secretion
<p>For nearly half a century, it was believed that during cell secretion, membrane-bound secretory vesicles completely merge at the cell plasma membrane resulting in the diffusion of intra-vesicular contents to the cell exterior and the compensatory retrieval of the excess membrane by endocytosis. …
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The electrophysiology of smooth muscle
… the intestine using external electrodes. He recorded action potentials similar to those which had been recorded from other excitable tissues during normal movements of the stomach and small intestine, and found that each movement was usually accompanied by a repetitive discharge. These …
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Protein-Protein Interactions That Regulate Neurotransmitter Release From Retinal Ribbon Synapses
… Release from Retinal Ribbon Synapses Photoreceptors and bipolar cells in the retina form specialized chemical synapses called ribbon synapses. This type of synapse differs physiologically from “conventional” chemical synapses. While “conventional” synapses exocytose neurotransmitter-filled …
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Tuning DNA binding and gene expression using zinc finger proteins and engineered promoters
… have focused on natural transcription factors (TFs),2 including the lac repressor, which produces a switch-like “all-or-none” response.3 In this project, we worked to develop a new system for transcriptional control based on tunable synthetic TFs, which are designed to yield programmable …
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A regulatory role for repeated decoy transcription factor binding sites in target gene expression
… both prokaryote and eukaryote genomes and the majority of repeats are concentrated in intergenic regions. These tandem repeats (TRs) are highly variable as the number of repeated units changes frequently due to recombination events and/or polymerase slippage during replication. While TRs have been …
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Transcriptional bursting in eukaryotic gene regulation : molecular basis and functional consequences
… intermittent bursts in a large variety of organisms. The statistics of mRNA expression can be described by two parameters: the frequency at which bursts occur (burst frequency) and the average number of mRNA produced within each burst (burst size). The mean steady-state abundance of mRNA is …
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Water-Soluble Deep-Cavity Cavitands: Synthesis, Molecular Recognition, and Interactions with Phospholipid Membranes
… deep-cavity cavitands provide a rare opportunity to study self-assembly driven by the hydrophobic effect. These molecular hosts dimerize in the presence of certain guest molecules to form water-soluble molecular capsules. These systems have given rise to numerous novel chemical phenomena …
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Sensory Coding and Olfactory Integration in Caenorhabditis Elegans
… external environments to guide meaningful behavior. The nematode Caenorhabditis elegans, for example, uses volatile cues to navigate toward food from a distance. How does an animal integrate the olfactory information from its environment? Here, I ask how multiple sensory neurons drive and shape …
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Induction and Maintenance of Synaptic Plasticity
… neuronal activation are believed to be at the origin of learning and long-term memory. Recent experiments suggest that these long-term synaptic changes are all-or-none switch-like events between discrete states of a single synapse. The biochemical network involving calcium/calmodulin-dependent …
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Barrier Heights and Diffusion Coefficients in Protein Folding
… proteins is that they are two-state. In other words, it is seemingly sufficient to invoke just two thermodynamic macrostates - folded and unfolded - to explain the experimental data with a transition-state like picture. Unfortunately, a chemical two-state model and the resulting conventional …
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Sperm utilization patterns in Gryllus integer (orthoptera: gryllidae
Sperm competition is the competition for fertilizations between ejaculates, within a female, following multiple mating. There are four sperm utilization or precedence patterns: first male precedence, where the first male to mate fertilizes most of the eggs laid by a female; last male precedence, …
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A comparative study of information processing capacity and cognitive style in learning disabled and normally achieving boys: a Neo-Piagetian approach
… investigated the relevance of a Neo-Piagetian theory of cognitive development in examining the competence/performance discrepancy associated with children who have specific learning disabilities. According to Neo-Piagetian theory (Pascual-Leone, 1970), a cognitive device called the M-operator is …
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Optically injected dual state quantum dot lasers
… to the excitable pulses seen in optically injected lasers. This thesis investigates the feasibility of optically injected dual state quantum dot lasers as artificial photonic neurons. Photonic waveguides are not as sensitive to centimetre long transmission lines as electronic circuits. …
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Is there a K in capacity? Evaluating the discrete-slot model of visual short-term memory capacity
Visual short-term memory (VSTM) is a fundamental cognitive structure that temporarily maintains a limited amount of visual information in the service of current goals. There is active theoretical debate regarding how limits in VSTM should be construed. According to discrete-slot models of capacity, …
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Variability and Dynamics of Apoptotic Events in Single Cells
<p>Apoptosis is a form of programmed cell death that is necessary for development and organism homeostasis. The early stages of apoptosis are marked by the permeabilization of the mitochondrial outer membrane, the release of cytochrome c and Smac from mitochondria, and the activation of the caspase …
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Efficient design and optimized crash-consistency support for hybrid memory systems
Hybrid memory systems (HMSs) pair different memory technologies within a uni ed main memory to combine the best features of those technologies, such as performance with capacity and durability. However, HMSs do not provide a cost-effective solution as a memory subsystem that can accommodate an …
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Regulation of Expression of a Retroviral Transforming Gene and its Cellular Homolog
… sarcoma virus (FSV) and its role in transformation. Specifically, it included the biochemical characterization of temperature-sensitive (ts) mutants of FSV, the identification of the product of a cellular gene homologous to the transforming gene of FSV, and the isolation and …
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