Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"Alkyl Halide"”.
-
Photoelectron Imaging of Iodide Centered Alkyl Halide Cluster Anions
<p>This dissertation presents results from cluster anion photodetachment experiments of the solvated iodide anion as a means of investigating electron molecule interaction. Due to the localization of the excess charge on the iodine atom, these experiments proceed analogously to electron scattering …
-
Utilization of the Phanerochaete chrysosporium ligninolytic system and the potential for toxaphene degradation
… persistent compounds including some alkyl halide chemicals. Cultivation of the fungus and the ability of the ligninolytic system to degrade the alkyl halide pesticide toxaphene were explored in pure liquid cultures. The effects of culture growth temperature and toxaphene concentration …
-
The chemistry of some organotellurium compounds
… evidence that the oxidative addition of an alkyl halide (RX=Mei, BunBr, BusecBr, ButBr, BrCH2-CH=CHCH2Br, and Br(CH2)4Br) to diphenyltelluride and reductive elimination of CH3SCN from Ph2(CH3)Te(NCS) proceeds via radical pathways. A mechanism is proposed for oxidative addition which involves …
-
New Strategies in Radical Chemistry and Their Application to the Construction of C(sp3)–C(sp3) Bonds in the Giese Reaction
… merges two electrophilic components (an alkyl halide and an acceptor) in the presence of a silane and visible light irradiation. Under these mild and extraordinarily simple conditions, visible light is anticipated to facilitate initiation derived from an interaction between the haloalkane …
-
Radical methods for the synthesis of aliphatic amines
… chapter 2 will describe a general carbonyl alkylative amination reaction, a successful version of which has been sought for over 70 years. Facilitated by visible light and a silane reducing agent, the operationally straightforward reaction forms tertiary amines via the coupling of aldehydes …
-
Synthesis and evaluation of novel ellipticines as potential anti-cancer agents
… one novel C11 derivative was produced using an alkyllithium reagent. A panel of novel ellipticinium salts encompassing a range of substitutions at the N2, C9 and N6 positions were prepared. Extensive derivatisation of the N10 position of isoellipticine was undertaken for the first time. Novel …
-
Towards Sacrificial Anode-Free Alkyne Electrocarboxylation
… source enabled a scalable sacrificial anode-free alkyl halide electrocarboxylation process. In contrast, this work revealed that Mg-based salts did not enhance the reactivity of sacrificial anode-free alkyne electrocarboxylation in an undivided batch configuration. Optimization of the direct …
-
Efficient Syntheses of Strong Binding Cryptands and their Derivatives for Supramolecular Polymer Synthesis
… acid (VII-1). Schemes yielding alcohol, alkyl halide, alkyne, and TEMPO functionality were followed, but failed. Currently, functionalized cryptand derivatives have not been achieved, future directions are proposed.
-
The formation and chemistry of certain heterocyclic dianions
… amide in liquid ammonia. The dianion underwent C-alkylation with numerous alkyl halides, to form 2-alkylglutarimides. Certain of these 2-alkyl derivatives were hydrolyzed to the corresponding 2-alkylglutaric acids. Carbonyl addition reactions of the glutarimide dianion with benzophenone, …
-
Mononuclear and Dinuclear Complexes of Allylated alpha-Diimines as Catalysts for the Polymerization of Ethylene
… compounds were functionalized with allyl or alkyl halide groups and then coupled with a metallocene or a half sandwich complex. Three different alpha-diimine compounds were synthesized and characterized by GC-MS, 1H NMR, and 13C NMR spectroscopy. These compounds are bearing allyl functions at …
-
INVESTIGATIONS OF HYPERVALENT IODINE COMPOUNDS IN ORGANIC TRANSFORMATIONS
… a surprising reaction between IBX or IBA and alkyl halides promoted by quaternary ammonium halides. In the absence of quaternary ammonium halides, no reaction occurred between IBX or IBA and alkyl halides. However, in the presence of quaternary ammonium halides, IBX or IBA and alkyl halides …
-
The Use of High-Throughput Experimentation to Accelerate the Development of Methods for Complex Amine Synthesis
… to the development of a new carbonyl alkylative amination reaction for the synthesis of α-branched amine scaffolds utilising a novel HTE workflow. The introduction of this thesis seeks to provide a comprehensive overview of the reaction types compatible with HTE techniques. Analysis of …
-
Sustainable strategies for alcohol halogenation
Alkyl halides appear widely in the structures of medicinal compounds and as key synthetic precursors in the pharmaceutical industry. Bimolecular nucleophilic substitution reactions of alcohols are commonly employed in the formation of new carbon–halogen bonds. However, achieving substitution at the …
-
Synthesis and Use of Chiral Surfactants.
<p>It has been previously shown that micelles formed from surfactants with chiral head groups serve to induce a chiral reaction medium, leading to enhanced enantioselectivities in the reaction products. This utilization of chiral surfactants will offer an economical alternative to traditional chial …
-
Synthesis, characterization and liquid crystalline properties of organometallic complexes of chromium, cobalt and platinum
… occurred chemoselectively to extend the hydroxy alkyl group, without affecting the oxime entities on the DH ligands. None of these complexes displayed mesogenic properties. This chapter also details the synthesis and characterization of the new complexes [Co(DH)₂(C₆H₄₀CₘH₂ₘ₊₁)(n-OST)] (m = 8, 10 …
-
Synthesis of Chiral Surfactants for Enantioselective Organic Synthesis.
<p>The first step of the synthesis of the hydrocarbon-based chiral surfactant <b>(2)</b> involved the methylation of (S)-leucinol to give (2S)-N-hexadecyl-N,N-dimethyl-(1-hydroxy-4-methyl-1-pentyl)-2-ammonium bromide (2.92g, 67%). The chiral surfactant was synthesized by reacting …
-
A Radical Approach to Photochemical Transformations Using Earth-Abundant Metals
… as an effective pathway to sequester transient alkyl radical species, introducing a powerful tool to utilize these reactive species for enhancing molecular complexity of feedstock chemicals. Herein, I will share my research of radical photochemical transformations enabled by earth-abundant …