Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Alkaloid Production"”.
-
TROPANE ALKALOID PRODUCTION BY DATURA
… rate limiting step(s) in the biosynthesis of the alkaloids followed by manipulation of the plant cell's genome so as to induce constitutive overproducers of alkaloids. Of particular importance to the project was the development of reliable methods for the detection and quantification of the …
-
A Catharanthus roseus mutant with trace levels of secologanin and monoterpenoid indole alkaloids does not express BIS1/BIS2 transcription factors and fails to activate iridoid biosynthesis.
… is the sole source of the monoterpenoid indole alkaloids (MIAs) that result in several essential anti-cancer chemotherapies as well as being an important source for other MIA derived pharmaceutical agents. Most of the alkaloid and pre-alkaloid iridoid pathway has been elucidated, but some …
-
Isolation and characterization of latex-specific promoters from Papaver somniferum L.
The pharmacologically important alkaloids morphine and codeine are found in latex of opium poppy (Papaver somniferum). Latex is harbored in laticifers, a specialized vascular cell-type. Isolation and characterization of latex-specific genes may provide a useful tool to metabolically engineer …
-
Impact of shade on cool-season forage mixtures for the Mid-Atlantic region
… harbors an endophyte that produces toxic ergot alkaloids. Diluting the sward with other forages can reduce ergot alkaloid concentrations, but it is unknown how shade impacts alkaloid production and productivity of different forage mixtures. This study tested the effects of increasing shade and …
-
From Forest Floors to Pharmacology: Elucidating Millipede Defensive Alkaloids for Drug Discovery
… possess repugnatorial glands, which store alkaloids as defensive compounds. However, they have also evolved unique characteristics that set them apart from all other millipedes, including distinct anatomy, group behavior, brood care, and the production of terpenoid alkaloids. Prior to 2020, …
-
Identification and Quantification using HPLC-ES/MS of Four Pentacyclic Oxindole Alkaloids in Uncaria tomentosa Wild Type
… a range of secondary metabolites such as alkaloids, triterpenes, flavonoids, glycosides, and procyanidins. The metabolites in U. tomentosa are valuable in the treatment a number of diseases like bursitis, which is the inflammation of bursae (small sacs) of synovial fluid in the body, …
-
Reprogramming alkaloid biosynthesis in Catharanthus roseus : synthetic biology in plants
… roseus) produces over 130 monoterpene indole alkaloid (MIA) natural products. Many of these compounds have pharmaceutical value, such as the anticancer agents vinblastine and vincristine. Unnatural modifications can impart novel bioactivity to the parent natural product. Advances in synthetic …