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Showing 1 to 6 of 6 for “"Alginate microcapsules"”.
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Encapsulation as a 3D model for human embryonic stem cell propagation and differentiation
… of single cell population of the hESCs in alginate microcapsules with an extended proliferation. A 5-stage ontogeny-based protocol for differentiation to beta cells was then applied to these cells. Encapsulated hESCs were successfully differentiated into definitive endoderm (DE); however, …
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Porcine islet encapsulation for treatment of type-1 diabetes using precision particle fabrication method
… presents single-step fabrication of core/shell alginate microcapsules using precision particle fabrication (PPF) system to demonstrate the feasibility of successful clinical xenotransplantation. PPF system has following capabilities: precise control of capsule size, ability to process material …
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Optimizing alginate-chitosan microcapsules using co-axial air flow method as 3d stem cell microenvironment
… the cell microenvironment. The benefits of using microcapsules are biocompatibility, biodegradability, nontoxicity, and formation under mild gelation conditions. In this study, the ability of the alginate microcapsules to control the proliferation and differentiation of mouse OCT4-GFP embryonic …
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Eliminating oxygen supply limitations for transplanted microencapsulated islets in the treatment of type 1 diabetes
… incorporating a perfluorocarbon emulsion into alginate microcapsules to enhance oxygen permeability in order to protect islets from hypoxia. The second method involves dispersing the islets into single cells and allowing them to reaggregate into cell clusters smaller than the original islet. …
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Development of an electronic aerosol atomisation system for generating three-dimensional (3D) cells in microencapsulations and microtissues characterisation
… system was proposed for producing calcium alginate microcapsules. The system was developed with the incorporation of a conventional syringe pump, a customised air pump and motor controller circuits. The microcapsules and 3D microtissues were biophysically characterised. For the output of …
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Immunoisolation Approaches for Islet Transplantation
… removing the requirement for immunosuppression. Alginate microcapsules are the most commonly used immunoisolation device which are typically implanted intraperitoneally. Intraperitoneal microencapsulated islet grafts are suboptimal, requiring at least double the number of islets to reverse …