Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Alcohol Withdrawal"”.
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Ethosuximide, a T-type Calcium Channel Antagonist, Reduces Alcohol Withdrawal Seizure
Alcohol is the third highest risk factor for health related problems in the world and leads to over two million deaths per year. Individuals abusing alcohol frequently cycle between drinking and withdrawal states, which among other adverse side effects can induce withdrawal seizures. Alcohol …
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Ethosuximide stabilizes sleep-related oscillations and reduces sleep fragmentation during alcohol withdrawal
… electroencephalography (EEG), as they pertain to alcohol withdrawal-related insomnia (AWI). AWI is an important clinical problem for chronic alcoholics undergoing treatment for alcoholism. The severity of AWI is highly correlated with increased risk of relapse. Furthermore, the current first-line …
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OPTICALLY-INDUCED POPULATION DISCHARGE THRESHOLD TESTING: A NOVEL INVESTIGATION OF A MURINE MODEL OF ALCOHOL WITHDRAWAL INDUCED CNS HYPEREXCITABILITY
Alcohol Use Disorder is a major, costly problem in society. Alcohol use is the third highest risk factor for health problems with much of that burden attributable to problems associated with alcohol withdrawal (WD). During WD the central nervous system (CNS) is described as being hyperexcitable. …
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Age-related differences in ethanol withdrawal, withdrawal-induced anxiety, cognition, and response to allopregnanolone.
… humans and rodents suggests that symptoms of alcohol withdrawal may be more severe in the elderly compared with younger adults. However, investigations of the effects of repeated ethanol intoxications and withdrawals on persistent deficits in motor and cognitive performance in aged rats are …
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A STUDY ON THE EFFECTS OF CHRONIC ALCOHOL AND WITHDRAWAL IN THE BASOLATERAL AMYGDALA OF SPRAGUE DAWLEY RATS: AFFERENT SPECIFIC MODIFICATION OF GLUTAMATERGIC NEUROTRANSMISSION
… suggests that long-term anxiogenic effects of alcohol withdrawal may be related to adaptations in BLA glutamatergic neurotransmission. The current studies serve to characterize glutamatergic signaling at multiple glutamatergic afferents into the BLA following chronic intermittent ethanol …
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ACQUIRED ALTERATIONS IN THALAMIC T-TYPE CALCIUM CHANNELS IN MODELS OF NEURONAL HYPEREXCITABILITY
… lobe epilepsy (TLE), and a model of chronic alcohol withdrawal following repeated intermittent exposures to ethanol. In particular, one T-type Ca2+ channel isoform, CaV3.2, was investigated for its role in producing a hyperexcitable population of neurons in a specific midline thalamic …
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A Study on the Effects of Chronic Alcohol and Withdrawal on the Glutamate, GABA, and Dopamine Systems in the Basolateral Amygdala of Sprague Dawley Rats
Alcoholism, a significant issue in society, has been correlated with anxiety disorders. Specifically, severe anxiety experienced during withdrawal from alcohol significantly increases the relapse rate in recovering alcoholics. Therefore, understanding the changes that occur in the brain regions …
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Effect of GABRA2 expression in the central nucleus of the amygdala on anxiety and alcohol's anxiolytic capacity in C57BL/6J mice
… one of the genes most frequently associated with alcohol-related behavior in human studies (Demers, Bogdan, & Agrawal, 2014). Polymorphisms in GABRA2 have been found to be associated with alcohol dependence, changes in drinking frequency, and alcohol’s stimulating and euphoric effects (Arias et …
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Auswirkungen von Clomethiazol auf den Schlaf gesunder Probanden
Die vorliegende Studie erfolgte im Rahmen der Suchtforschung, die unter anderem die Optimierung der Alkoholentzugstherapie anstrebt. So wurde die Auswirkung von Clomethiazol, einem in der gegenwärtigen Entzugstherapie häufig angewandtem Medikament, auf den Schlaf bei 10 gesunden Probanden …
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Uso de dexmedetomidina como tratamiento coadyuvante de síndrome de abstinencia alcohólica: revisión sistemática
… manejo coadyuvante de síndrome de abstinencia a alcohol (SAA) a través de la búsqueda de evidencia científica. Metodología: se realiza una revisión sistemática de literatura publicada y no publicada desde enero de 1989 hasta febrero 2016 en PubMed, Embase, Scopus, Bireme, Cochrane library y en …