Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Alcohol Addiction"”.
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Cognitive Function in the Alcohol Addiction Treatment Population
<p>Chronic alcohol abuse has been linked to several cognitive deficits, such as problems with spatial processing, decreased executive functioning, impaired verbal fluency, poor working memory, response inhibition, and social problems such as aggression and social deviance. In order for patients to …
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THE ROLE OF DOPAMINE D3 RECEPTOR IN ALCOHOL ADDICTION AND SCHIZOPHRENIA
… several neuropsychiatric disorders such as drug addiction and schizophrenia (Leggio et al., 2016). D3R, acting as autoreceptor, regulates the activity of DAergic neurons throughout the mesolimbic, mesocortical and nigrostriatal DAergic pathways (Gobert et al., 1995; Tepper et al., 1997; Diaz et …
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REGULATION OF DOPAMINE TERMINAL RELEASE IN THE NUCLEUS ACCUMBENS: IMPLICATIONS FOR ALCOHOL ADDICTION
Alcoholism and drug addiction are both characterized by continued substance abuse despite adverse consequences. Dopamine signaling in the nucleus accumbens is thought to encode reward and reinforcement, and aberrations in dopamine signaling are suggested to mediate some of the maladaptive …
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Alcohol addiction treatment in Cape Town: Exploratory investigation of the public-private mix
… and safety are compromised by the effects of alcohol addiction. Some of the consequences include transmission of infectious diseases, disproportionate use of medical and social services, traffic accidents, and street crimes. Additionally, when dealing with alcohol addiction, many expenses are …
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Investigation of Carbamathione Pharmacokinetics and Pharmacodynamics by In Vivo Microdialysis and Capillary Electrophoresis
… basis for the use of the drug disulfiram for alcoholism is its inhibition of liver aldehyde dehydrogenase (ALDH2). Recent studies have reported that disulfiram exhibited an anti-craving effect with both alcohol addiction and cocaine dependence. Inhibition of ALDH2 cannot explain disulfiram's …
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Alcohol-induced Locomotor Activity in Zebrafish is Mediated by Activation of the Dopaminergic System
Alcohol addiction is a major unmet medical issue with current pharmacological treatment options being limited. Alcoholâ s locomotor stimulant effect in animals is thought to parallel the euphoric effects of alcohol consumption in humans, yet the mechanisms underlying this behavioural response is …
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Effetto dell’etanolo sullo stato di metilazione del gene che codifica per la neurotrofina “Brain-Derived Neurotrophic Factor”
Alcohol addiction is thought to depend on molecular and cellular adaptations in the brain that result from chronic drug exposure (Fitzgerald and Nestler, 1995 ). This suggests that chronic alcohol abuse involves stable changes in the brain at the molecular and cellular levels responsible for …
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Nurturing the Event: A Trauma-Informed Psychosocial Analysis of Conversions to Christianity and Desistance from Crime
… onset, and for two-thirds of the sample, drug/alcohol addiction. However, while therapy helps address unresolved trauma, it often fails to heal the wound it leaves. The conversion process and newfound spirituality appeared to resolve this. The thesis will emphasize the importance of …
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Beauty and the treatment of addiction
Drug and alcohol addiction are highly destructive, reaping significant damage on society, on addicts, and on their families and friends. The past century has seen a vast increase in the treatment of addiction, but these methods have failure rates of 50% or greater. This work seeks an alternative …
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Gambling addiction and life meaning
… been studied extensively. One proposed cause for addiction, which has been used in studying alcohol and drug abuse, is a lack of meaning in the addict's life. However, a causal link between life meaning and gambling addiction has not yet been examined. This study used a sample of 355 normal people …
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Bloodlines
… mental and physical illnesses, from cancer to alcohol addiction, to career changes, to the often dysfunctional and displaced family ties that distance and adulthood have not severed. In "Searching," I write the narrative of the ongoing search for my birthmother, and how the search complicates …
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THE EFFECT OF NALTREXONE ON NICOTINE-INDUCED CONDITIONED PLACE PREFERENCE IN RATS
… FDA-approved for the treatment of opioid and alcohol addiction in humans. Using standard two-chamber shuttleboxes, we first sought to establish a place preference for nicotine in rats, and once this was achieved, we sought to block nicotine place preference with naltrexone. In the first …
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Evaluating Cognitive Changes in Patients Receiving Outpatient Alcohol Treatment
<p>Chronic alcohol use has been linked to various physical health concerns, neurological changes, and cognitive deficits. Research has shown that some of these neurologic and cognitive deficits can improve over time following detoxification and abstinence; however, the exact nature or timeline of …
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Understanding addiction stigma: Examining desired social distance toward addicted individuals
… towards individuals with substance dependence to alcohol, marijuana, and heroin. This study found that for marijuana and heroin, familiarity had an indirect effect, through perceived dangerousness and fear, on desired social distance. Furthermore, perceived dangerousness had a direct and indirect …
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Factors that Affect Treatment Compliance among Individuals with Mental Illness
… and program removals they had experienced. Alcohol addiction severity and social support at intake were found to be significant predictors of treatment adherence at six-month follow-up. These findings will be discussed as they pertain to the implications for identifying and understanding the …
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Perceived purpose and sources of meaning as protective factors for substance use amongst emerging adults across South Africa
… Conclusively, a correlation was found between alcohol addiction and the source of meaning dimension, ‘Relationship Status,’ alongside the self-transcendence item, ‘I am involved in community service.’ These findings contribute insights into protective factors against substance use within SA and …
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Treatment Effects Related to EEG-Biofeedback for Crack Cocaine Dependency: Changes in Personality and Attentional Variables
… demonstrated as effective in the treatment of alcoholism, as evidenced by Peniston and Kulkosky's research efforts. These neurotherapy pioneers evaluated the efficacy of alpha-theta brain wave biofeedback as a treatment for chronic alcohol abuse, citing 80% abstinence rates as measured by …
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Pituitary adenylate cyclase-activating polypeptide regulates excessive alcohol consumption
Alcoholism results from an interaction between genetic and environmental factors. However, the neurobiological mechanisms mediating the propensity to consume excessive amounts of alcohol are still not well understood. Using genetically selected alcohol-preferring rats, a well-established animal …
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Lentiviral-mediated gene delivery to investigate the functional role of neuropsychiatric genes
… disorders such as Parkinson’s Disease, alcohol addiction and mood disorders. On the other hand, a gene of unknown function, AUTS2 (Autism susceptibility candidate 2), has recently been associated with alcohol consumption in a GWAS meta-analysis performed by our group. Interestingly, it …
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