Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Alanine aminotransferase (ALT)"”.
-
PROTECTION OF ISCHEMIA REPERFUSION INJURY IN MURINE LIVER BY GENE SILENCING OF COMPLEMENT 3
… IRI was evaluated using histopathology, serum alanine aminotransferase (ALT), and aspartate aminotransferase (AST). Neutrophil accumulation was determined by myeloperoxidase assay. Oxidative stress was assessed by malondialdehyde and reactive oxygen species levels. In comparison with control …
-
Association Between Metabolic Markers and Amount of Alcohol per Occasion in Korean Men
… C-reactive protein(hs-CRP), albumin, aspartate aminotransferase(AST), alanine aminotransferase(ALT), r-glutamyl transpeptidase(r-GT) and uric acid. SUBJECT: A total 2,996 healthy men above 20 years of age who had visited a health promotion center in a university hospital from January, 2006 to …
-
Development of Electrochemical Biosensors for Potential Liver Disease Detections of ALT & AST and Application of Ionic Liquid into Biosensing-Modified Electrodes
… of the biomarkers relevant to liver diseases: alanine aminotransferase (ALT) and aspartate aminotransferase (AST). The proposed biosensor technology provided a useful tool for potential clinical-screening of liver status.Iridium (Ir) nanoparticles possessed excellent electrocatalytic activity …
-
Prevalence of Hepatitis B in HIV infected persons: choice of antiretroviral therapy regimen and implications for screening
… of Hepatitis B surface antigemia (HBsAg) in healthy HIV positive persons screened for a vaccine trial and the proportion of those eligible for antiretroviral therapy that were receiving optimal antiviral treatment, namely tenofovir and/or lamivudine. The relationship between Hepatitis B …
-
Emergence of Adefovir-resistant Mutants after Reversion to YMDD Wild-type in Lamivudine-resistant Patients
… no differences in HBV DNA suppression and serum alanine aminotransferase (ALT) normalization between patients treated with the combination of LAM and ADV and those receiving ADV alone. A recent study showed that switching to ADV in patients with LAM-resistant HBV was associated with higher risk …
-
Model-Informed Drug Development of Riluzole for Neuroprotection in Acute Spinal Cord Injury: Integrating Pharmacokinetics, Pharmacodynamics, and Clinical Outcomes for Precision Medicine
… were then used to evaluate relationships of alanine aminotransferase (ALT), a marker of hepatic safety, with riluzole exposure and phosphorylated neurofilament heavy chain (pNFH), a biomarker of axonal injury. These models captured subtle exposure-related effects not evident through …
-
The effect of acupuncture on people with hepatitis C virus : a randomised controlled pilot study
Background: The use of Complementary and Alternative Medicine (CAM) in Australia has been steadily increasing. This has resulted in many people infected with Hepatitis C Virus (HCV) consulting CAM practitioners in the hope of alleviating some of the debilitating symptoms associated with this viral …
-
Hepatic stellate cell heterogeneity and function during the hepatic regenerative response
… plasma levels of hepatic enzymes (including alanine aminotransferase, ALT), and histological examination of Periodic Acid-Schiff-stained tissue sections. RESULTS: (1) scRNA-seq analyses of PDGFRb+ cells from healthy and APAP-injured mouse livers identified HSC heterogeneity, with two distinct …
-
An in vitro and in vivo hepatotoxicity study of an aspalathin- rich green rooibos extract
… often occurring due to the interaction of drugs. Although different methods have been employed in the diagnosis of drug-induced hepatotoxicity, none have accurately proven the hepatotoxic effect of drug-drug interactions or drug-herb interactions. Flavonoids of aspalathin-rich green Rooibos …
-
American skullcap (Scutellaria lateriflora L):a study of its effects on mood in healthy volunteers
… following its chronic administration to healthy volunteers. Based on a randomised, double-blind, placebo-controlled crossover design, it examined the effects of S. lateriflora on psychologic symptoms using the Beck Anxiety Inventory (BAI) and the Profile of Mood States (POMS) …
-
Integrated imaging and circulating biomarkers for the assessment of drug-induced hepatotoxicity
… liver injury (DILI) is a major burden for health care systems and a principal reason for attrition during drug development. Prediction of clinical DILI remains difficult and diagnosis is usually based on exclusion using blood-based biomarkers for cell injury. Currently used chemistry …
-
The UP AMIGOS project: Testing the predictive validity of the 2007 Pediatric Expert Committee Recommendations in Latinos
… in Central Mexico. Participants underwent a health screen that included: a questionnaire, anthropometric measurements (i.e. height, weight, waist circumference, blood pressure), a physician-conducted history and physical, and venipuncture for blood biomarkers. Analysis. In order to determine …