Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"Ajuba LIM"”.
-
Role of the Ajuba LIM Proteins in Epithelial Growth Regulation
The mammalian Ajuba LIM proteins: Ajuba, LIMD1, WTIP) are cytosolic adapter proteins recruited to nascent epithelial adherens junctions, where they are thought to contribute to junctional assembly and/or stability. They also shuttle into the nucleus acting as corepressors of the Snail family of …
-
Negative Regulation of the Hippo Pathway by the Ajuba LIM Proteins
… Previous work from our lab has identified the Ajuba LIM proteins as novel negative regulators of the Hippo pathway in both Drosophila and mammals. However, the mechanism by which the Ajuba LIM proteins prevent Hippo pathway activity is not known. Using contact inhibition of proliferation as a …