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Showing 1 to 6 of 6 for “"Aiolos"”.

  1. Mobile Cloud Computing: A Comparison Study of Cuckoo and AIOLOS Offloading Frameworks

    Kaddour, Inan, Kaddour, Inan, 1983-University of North Florida. School of Computing

    unf Repository record

  2. Implication of Bcl-2 family members in apoptosis signalling pathways triggered by growth factor deprivation

    Fleischer, AarnePublikationsserver der RWTH Aachen University2003

    … for the lymphoid-specific transcription factor Aiolos that was found to be associated with the pro-survival Bcl-xL protein in IL-4-deprived, but not IL-4-stimulated T-lymphocytes. The phosphorylation status appeared to be important since dephosphorylation of Aiolos and Bcl-xL increased their …

    aachen Repository record

  3. The Role of IkZF Factors in Mediating TH1/TFH Development and Flexibility

    Bharath Krishnan Nair, SreekumarVirginia Tech2020

    … other members within the IkZF family, Ikaros and Aiolos. Aiolos in turn collaborate with STAT3, induces Bcl-6 expression within these cells, thus promoting these cells to exhibit characteristic features of TFH cells. The work in this dissertation hopes to advance our understanding of the …

    vt Repository record

  4. Insights Into the Regulatory Requirements for T Follicular Helper Cell Development

    Powell, Michael D.Virginia Tech2019

    … zinc finger transcription factors Ikaros and Aiolos cooperate to regulate Bcl-6 expression in these TFH-like cells. Collectively, the work in this dissertation significantly advances our understanding of the regulatory mechanisms that govern TFH cell differentiation, setting the basis for the …

    vt Repository record

  5. Investigation of the anticancer activity and mechanisms of zinc diethyldithiocarbamate in multiple myeloma

    Rajendran, GowthamUniversity of Wolverhampton2023

    … expression of cereblon (CRBN), Ikaros (IKZF1), aiolos (IKZF3) and Interferon regulatory factor-4 (IRF4), a significant downregulation of protein levels was observed after treating the MM cell lines with sub-cytotoxic concentrations of ZnDDC (2-5 μM). After exposure to low concentration of ZnDDC, …

    wlv Repository record

  6. Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia

    Miller, Christopher B.2016

    … <em>IKZF1</em> (IKAROS), and <em>IKZF3</em>(AIOLOS). These findings suggest that direct disruption of pathways controlling B-cell development and differentiation contributes to B-progenitor ALL pathogenesis. Moreover, these data demonstrate the power of high-resolution, genome-wide approaches …

    tenn-hsc Repository record