Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Ah receptor"”.
-
Vliv cytochromu b5 na enzymovou kinetiku hydroxylace Sudanu I lidským cytochromem P450 1A1
… monooxygenases (MFO). Isoform 1A1 is a extrahepatic form found mainly in the lung and other tissues. It is strongly induced by polycyclic aromatic hydrocarbons and their derivatives via the Ah receptor. As a marker reaction for this enzyme can be used hydroxylation of Sudan I, which has …
-
Evidence that ARNT plays a role in the regulation of the immunoglobulin heavy chain enhancer and identification of a putative ARNT ligand
… In our study we tested the function of ARNT (Ah receptor nuclear translocator) at the IgH (immunoglobulin heavy chain) enhancer. We were able to determine that ARNT appears to partially down-regulate activation at the IgH enhancer by Pan-1 in transient transfection assays by cotransfection of …
-
Immunological and hematological biomarkers for contaminants in fish-eating birds of the Great Lakes
… that halogenated aromatic hydrocarbons (HAHs), which include PCBs and dioxin, are associated with developmental and population-level problems in fish-eating birds of the Great Lakes. Other studies have shown that perinatal exposure to HAHs causes thymic atrophy and suppresses T lymphocyte …
-
Chemical-sensitive genes in zebrafish (Danio rerio) early development - identification and characterisation of differential expression in embryos exposed to the model compound 3,4-dichloroaniline
… involved in biotransformation pathways (cyp1a, ahr2), stress response (nrf2, maft, ho-1) and cell cycle control (fzr1). Differential expression upon 3,4-DCA exposure was detected below the LOEC (lowest observed effect concentration = 6.2 µM) of survival or developmental disorders of the embryo …
-
Natürliche Lebensmittelinhaltsstoffe als Liganden des Ah Rezeptors - Identifizierung und Charakterisierung von Beta-Carbolinen mit AhR Ligandenpotential mittels funktioneller Bioassays
… als natürliche Liganden des Ah Rezeptors („aryl hydrocarbon receptor“) vorgestellt. Der Ah Rezeptor ist ein liganden-abhängiger Transkriptionsfaktor, der an der Expression zahlreicher Metabolismusenzyme beteiligt ist. Im Mittelpunkt unserer Untersuchungen anhand von …