Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Agouti viable yellow"”.
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Variable methylation of endogenous retroviruses: epigenetic inheritance, environmental modulation, and genetic modifiers
… expression. Previous work has shown that, at the Agouti Viable Yellow (Avy) locus, an IAP insertion provides an alternative promoter for the Agouti coat colour gene. Variable methylation of this IAP is correlated with coat colour expressivity. In addition, the Avy allele exhibits transgenerational …
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Mechanisms of epiallelic variation in mouse
… gene expression. The best known example is the Agouti viable yellow mutant mouse, where variable DNA methylation at a TE insertion leads to coat colour differences among genetically identical mice. Such loci are termed “epialleles”. In mice, the intracisternal A-particle (IAP) subclass of TEs …
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Variable DNA methylation in the mouse genome: repetitive elements, unique regions and functional implications
… from an IAP insertion into the endogenous Agouti gene locus which is variably silenced between isogenic individuals. Variable DNA methylation at the IAP inversely correlates with ectopic expression of Agouti, resulting in a spectrum of coat colours between littermates. This, and other …