Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Ago1"”.
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The interactions of the cucumber mosaic virus 2b protein with the viral 1a and host Argonaute 1 proteins
… with the host RNA silencing factor Argonaute 1 (AGO1). The consequent inhibition of AGO1 activity induces developmental symptoms such as stunting and organ deformation in CMV-infected plants. In *Arabidopsis thaliana*, if 2b-induced inhibition of AGO1 is too strong this de-represses resistance …
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Studies of Resistance to Aphids and Viruses in Arabidopsis thaliana and Capsicum annuum
… the resistance to aphids observed in Arabidopsis ago1.25 mutant plants. Aphid growth rates and fecundity on ago1/cyp82C2 or fox1/ago1 mutant plants did not significantly differ from aphid performance on wild-type plants. This indicates that deregulation of 4-OH-ICN biosynthesis does not contribute …
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Interactions between Cucumber mosaic virus proteins and host proteins
… of host gene expression by binding ARGONAUTE 1 (AGO1). In Arabidopsis, complete inhibition of AGO1 activity is counterproductive to CMV since this triggers antibiosis against aphids and stimulates resistance mechanisms by AGO2. The CMV 1a protein (a replicase component) is able to moderate …
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Exploring the molecular architecture of proteins: Method developments in structure prediction and design
… of protein molecule more than half a century ago1, our understanding of protein structure is improving only incrementally. While computational analysis and experimental techniques have helped scientist view the structural features of proteins, our concepts about protein folding remain at the …
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MicroRNA-184: A Multifaceted Regulator of Epidermal Keratinocyte Biology
… of miR-184 reduced migration. Studies on AGO1-4 transcripts identified that AGO4 mRNA was the most abundant AGO in human epidermal keratinocytes and revealed no reduction of AGO2 expression in response to enhanced miR-184 levels during differentiation. Furthermore, both AGO1 and AGO4 were …
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The spatial and temporal regulation of the transcriptome during plant development
… hook region. We also detect higher expression of AGO1 in the apical hook, a key player in small RNA regulatory pathway, and show that Arabidopsis ago1 mutants display an impaired photomorphogenesis in the seedling apex. Using next-gen sequencing, we show that many miRNAs are responsive to a …
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Molecular Pathology: Potential Biomarkers For The Detection Of Down Syndrome Pregnancies
… located on chromosome 21 against LEPROT and AGO1 genes located on on chro- mosome 1 as reference genes. The T21, T18 and T13 multiplex assay tar- geted VPS26C gene located on chromosome 21, BRCA2 gene located on chromosome 13 and LPIN2 gene located on chromosome 18 against AGO1 gene located …
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Investigation of miRNAs Expression in a Citron-Kinase Mutant Model of Microcephaly
… link between Cit-K and a protein Argonaut 1 (AGO1), which is required for proper functioning of the miRNA machinery (2). Experiments characterizing the role of miRNAs in the developing cortex demonstrate the requirement of miRNAs for differentiation of neural progenitor cells starting at …
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Precise Temporal Regulation of Ribonucleoprotein Complexes during the Drosophila Maternal-to-Zygotic Transition
… expression at 31B (ME31B) and Cup, as well as AGO1 and the CCR4-NOT deadenylase to regulate the translation and stability of hundreds of maternal mRNAs, and this regulation is required for proper development through the MZT. However, regulation of maternal proteins, including these RBPs is not …
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Dynamic Shuttling of AGO2 to the Nucleus Relieves MicroRNA Repression
… enzyme, DROSHA, and microRNA effector proteins, AGO1-4 and TNRC6A-C, on microRNA expression. Our findings help to define the boundaries of RNAi in a widely used cell line, HCT116, by refining a subset of abundant microRNAs that are DROSHA-dependent, associated with Argonaute proteins, and most …
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Investigating the role of RNA 5- methylcytosine on ribosomal and transfer RNAs in Arabidopsis thaliana
… RNA silencing proteins RDR6, DCL2, DCL3, DCL4, AGO1, AGO3, AGO4, AGO5, AGO7, AGO9 and AGO10. Two sRNAs from 5’-half tRNAAsp appear to silence embryo-defective genes, At1g67490 and At1g32490, thereby leading to embryo lethality. Taken together, my research addressed functions of m5C …
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RNAi em Colletotrichum lindemuthianum: caracterização das proteínas-chave e desafios para a aplicação
… do gênero Colletotrichum. A expressão dos genes AGO1, RdRP3 e DCL1 do fungo na interação com a planta variou ao longo do tempo e da linhagem avaliada. Foram obtidos 18 e 180 transformantes de C. lindemuthianum e C. truncatum, respectivamente, expressando GFP. A produção de dsRNAs apresentou baixo …
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Investigation sur la fonction du gène AGO5 dans le développement des plantes et la défense antivirale
… Dans l'interaction Arabidopsis-virus, AGO1, AGO2 et AGO4 sont parmi les protéines AGO les plus étudiées. Ceci est principalement dû à l'ordre dans lequel elles ont été identifiées, à leur implication dans de nombreux processus de développement ou à leur rôle dans la défense antivirale …
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Functional study of miRNA-mRNA interactions in malaria mosquito An. gambiae
… and their association with Argonaute 1 (Ago1) and Argonaute 2 (Ago2) in the malaria mosquito Anopheles gambiae (An. gambiae) during the 72-h period immediately after blood feeding. I found the abundance and Ago loading of most of the mature miRNAs were relatively stable after blood …