Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 91 for “"Age of Onset"”.
-
Can childhood animal cruelty be learned?: examining age of onset and recurrency
… (2012) study. It examines the potential for the onset and recurrence of childhood animal cruelty to become a learned behavior, specifically in terms of how demographic characteristics and childhood experiences, such as witnessing animal cruelty and being mentally and/or physically abused, …
-
Alzheimer's disease: Age of Onset Modifier Genes in the World’s Largest Pedigree
… disorder that accounts for 60-80% of dementia cases, especially in people over 65 years. More than 36 million people had AD or related dementias in 2010, and more than ~116 million will be diagnosed by 2050. Over the last 30 years, our group has studied the largest multigenerational …
-
Alzheimer's disease: Age of Onset Modifier Genes in the World’s Largest Pedigree
… disorder that accounts for 60-80% of dementia cases, especially in people over 65 years. More than 36 million people had AD or related dementias in 2010, and more than ~116 million will be diagnosed by 2050. Over the last 30 years, our group has studied the largest multigenerational …
-
THE RELATIONSHIP BETWEEN AGE OF ONSET OF DRUG USE, DRUG DEPENDENCE, MENTAL DISORDERS, AND OFFENSE TYPE AND SEVERITY
<p>This study examines the relationship between age of onset of drug use and later drug dependence, and that of age of onset of drug use and current offense type/severity. In addition, it investigates the relationship between mental disorders, drug dependence, and current offense type/severity. …
-
The acquisition of finiteness in English by child second language learners in instructed contexts: age of onset and L1 effects
This thesis examines the acquisition of finiteness in English by child L2 learners by investigating the impact of the age of onset and the role of the learners’ L1 on their L2 acquisition. Following Meisel’s hypothesis that children older than 4 will resemble adult L2 acquisition in the domain of …
-
An Investigation of Psychosocial Functioning for Children and Adolescents Diagnosed with Bipolar Disorders
This study provides a literature review of how the various sub-types of bipolar disorders are related to a child's daily functioning. Also, this study examined the age of onset of the disorder as it is related to psychosocial functioning. Specifically, age of onset was compared with psychosocial …
-
Sex Differences in Psychotic Symptoms: Understanding the Role of Psychosocial Influences
… differences in psychosis and the potential role of psychosocial variables in these differences. A sample of 51 men and women with psychosis completed a questionnaire about clinical variables (age of onset, age of first contact with services, age of first hospitalisation, number of …
-
Delinquency, Academic Underachievement, and Attention Deficit Hyperactivity Disorder: A Longitudinal Investigation of Developmental Sequencing and Interrelated Risk Factors
This study utilized a longitudinal sample of 503 boys to investigate the developmental sequencing of delinquency, AU, and ADHD, as they unfold over time. Age of onset analysis, followed by a within subjects analysis, was conducted. Common risk factors among delinquency, AU, and ADHD, including …
-
A review of cases of motor neurone disease seen at Groote Schuur Hospital from 2005 to 2010
… disorder in which selective degeneration of the motor neurones of the brain and spinal cord occurs. Progressive weakness of limb, bulbar and respiratory muscles eventually results in death. Most descriptive and epidemiological studies of MND have been performed in the industrialized …
-
Speech Intelligibility and Bilingualism: The Effects of Age of Acquisition
One of the central questions of second language acquisition research has been what affect age of acquisition has on the language learner's eventual proficiency in a second language. Researchers have tried to determine whether there is a strong correlation between age of onset and fluency in the …
-
The Predictive Value of Complex PTSD Symptoms on Resting High-Frequency Heart Rate Variability
Although the negative consequences of traumatic exposure across various domains of functioning have been well-documented, gaps and discrepancies continue to exist in the understanding of the impact of complex trauma, such as interpersonal violence (IPV), and how outcomes may vary across diverse …
-
Studies of the efficacy of Ribonucleotide Reductase inhibition in preclinical models of Acute Myeloid Leukemia in combination with standard and novel therapeutics
… Myeloid Leukemia (AML) is an aggressive disease of the marrow with approximately 18,800 new cases each year. The elderly population represents the bulk of AML patients with a median age of onset of 70. More than 70% of AML patients are over the age of 60, and for this group the 5 year overall …
-
Characteristics of Marijuana Users Compared to Multiple Drug Users
… drug use behavior in a self-described sample of users. Comparisons are made between subjects whose only illicit drug use is marijuana and those who use both marijuana and other drugs. Data are from the DRUGNET study (1996, 1998, 1999), a multi-panel study conducted over the internet from 1996 …
-
SYNTHESIS, CHARACTERIZATION, IN VITRO EVALUTION, AND PRECLINICAL PROFILING OF β-CYCLODEXTRIN POLYROTAXANE FAMILIES FOR USE AS POTENTIAL NIEMANN-PICK TYPE C THERAPEUTICS
… recessive genetic disorder featuring a loss of proteins responsible for unesterified cholesterol (UC) trafficking through the late endosomes/lysosomes (LE/LY) of every cell of the body. Disruption of this pathway leads to abnormal accumulation and storage of UC and other lipids. A broad range …
-
Cognitive Differences Between Congenitally and Adventitiously Blind Individuals.
… historical perspective regarding the theories of cognitive development and the cognitive functioning of individuals with visual impairments, that sight plays a major role in the development of certain cognitive processes. However, the affects of visual impairment on cognitive development remain …
-
Environmental and age effects on methylation changes in human brain and blood cells
… may 1 e associated with disease, aging, the rate of aging and genetics. In this thesis, age is accurately predicted from DNA methylation in brain and blood tissues using two different algorithms, Random Forest and Linear Regression. Relationships between DNA methylation, genetics, disease and …
-
CHARACTERIZING DRUG-RESISTANCE IN ADULTS WITH NEW-ONSET EPILEPSY
… reporting the factors involved in or the rate of drug-resistant epilepsy (DRE) in adults with new-onset epilepsy (NOE). This prospective cohort study characterizes DRE and risk factors in a pure adult cohort with NOE or newly diagnosed epilepsy (NDE). There are very few studies reporting the …
-
A Comparison of the Frontal Variant of Alzheimer's Disease with Typical Alzheimer's Disease and Frontotemporal Dementia
A frontal variant of Alzheimer's Disease (FvAD) has been described in the literature in which prominent frontal lobe dysfunction accompanies typical temporal and parietal lobe dysfunction in the early stages of the illness. However, no study has investigated how executive deficits and …
-
Food Intake and Physical Activity Assessment of Native American Children with Acanthosis Nigricans and their Friends
… be highly prevalent among Native Americans. The age of onset of acanthosis nigricans closely parallels the onset of obesity among Winnebago/Omaha children. The combination of obesity with acanthosis nigricans is a key sign of high risk for the development of non-insulin dependent diabetes …
-
Associations Between Personal Cancer History and Lung Cancer Risk
… assess their predictive utility. Characteristics of interest included the number, anatomical site(s), and age of onset of previous cancer(s). Data from the Prostate, Lung, Colorectal and Ovarian Screening (PLCO) Cancer Screening Trial (N = 154,901) and National Lung Screening Trial (N = 53,452) …
Page 1 of 5