Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"Adverse pregnancy outcomes"”.
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Axis of placental ageing in adverse pregnancy outcomes
Background: Pre-eclampsia (PE), an adverse pregnancy outcome affects 2-5% pregnancies worldwide and significantly adversely impacts both maternal and fetal outcomes. Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to reach normal growth potential within the uterus as …
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Role of Chlamydia trachomatis infection in adverse pregnancy outcomes
… transmitted bacterium, has been associated with adverse pregnancy outcomes including controversial data on miscarriage, intrauterine growth restriction and low birth weight, however the causative mechanisms are unknown. A successful pregnancy requires normal endometrial stromal cell (ESC) …
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Applications of metabolomics to study the pathophysiology of adverse pregnancy outcomes
… a potential therapeutic agent on the metabolome. Adverse pregnancy outcomes, such as small for gestation age (or fetal growth restriction), spontaneous preterm birth, and pre-eclampsia, lead to high maternal and fetal mortality and morbidity rates. However, despite research efforts to date, their …
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Adverse pregnancy outcomes and the long-term risk of maternal kidney disease
Background: Adverse pregnancy outcomes, including hypertensive disorders of pregnancy (HDP), preterm delivery, foetal growth restriction, gestational diabetes (GDM), and pregnancy loss, have been associated with the risk of maternal chronic disease, particularly cardiovascular disease. Less is …
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Pareto Task Inference Analysis of Single-Cell RNASequencing of Human Placenta Reveals Biological Insightsinto Adverse Pregnancy Outcomes
Adverse pregnancy outcomes (APOs), such as preeclampsia, fetal growth restriction, and preterm birth, occur in 10-15% of pregnancies. There is limited knowledge of how the cellular states in the placenta and decidua tissues are altered in women with particular APOs or may contribute to APOs. …
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Does an antenatal educational programme decrease adverse pregnancy outcomes among obese pregnant women? A feasibility study in Kurdistan Region of Iraq.
… research about the incidence of obesity during pregnancy and its outcomes has not previously been investigated in the Kurdistan region of Iraq. The aim of this study was to explore the appropriateness of an educational programme for obese women and its influence on pregnancy outcomes with a view …
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The impact of maternal chronic hypertension and chronic kidney disease on the risk of adverse pregnancy outcomes and long-term cardiovascular disease: a population-based epidemiology study
… decades, it is still unclear whether the risk of adverse pregnancy outcomes (APOs) among women with CH and/or CKD has decreased. There is limited evidence on the association between antihypertensive treatment and APOs in women with CH. Although there is evidence that women with a history of APOs …
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The effect of maternal oral health on pregnancy outcomes
Adverse pregnancy outcomes such as preterm birth and low birth weight are major causes of maternal and neonatal morbidity and mortality. Increasing evidence points to an association between periodontal disease and adverse pregnancy outcomes and thus a better understanding of the nature of this …
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Hemaglobinopathy and Pregnancy Outcomes: A Historical Cohort Study
Pregnancy in women with hemoglobinopathy has been associated with an increased risk of adverse pregnancy outcomes. We conducted a historical cohort study using Discharge Abstract Database for the fiscal year 1991-1992 through 2007-2008. We estimated the frequency of pregnant women with …
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Sleep Disordered Breathing and Pregnancy: Prevalence and Outcomes at Delivery
… /> Sleep Disordered Breathing (SDB) during pregnancy is associated with maternal and neonatal morbidity, and in-hospital mortality. A recent prevalence study using the Nationwide Inpatient Sample reported an obstructive sleep apnea (OSA) prevalence of 7.3 per 10,000 in 2013, a rate of 24% …
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Antiretroviral therapy use during pregnancy and adverse birth outcomes in South African women
… suggest antiretroviral therapy (ART) use during pregnancy may be associated with adverse pregnancy outcomes. Given the large numbers of pregnancies exposed to ART, better understandings of potential associations with commonly used ART regimens and adverse pregnancy outcomes is critical. With the …
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Roles of Group B Streptococcal membrane proteins in virulence and protection
… tract in up to 20% of women worldwide. During pregnancy, GBS is a leading cause of invasive infections associated with adverse pregnancy outcomes including preterm births, neonatal infections, and stillbirths. In addition to its role as a pregnancy-associated pathogen, GBS infection rates in …
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UNDERSTANDING PLACENTAL IMMUNITY: CYTOKINE CONTROL OF CONGENITAL VIRAL INFECTION
During the critical developmental period of pregnancy, there are substantial consequences to viral infection. Following maternal infection, certain viruses can traverse the placental barrier, establish infection in the fetus, and cause adverse pregnancy outcomes or congenital disease. To combat …
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Effect of prenatal zinc supplementation on malarial morbidity, pregnancy anaemia and birth weight
… Ghana that continue to impact negatively on pregnancy outcomes, despite interventions being put in place to address them. The reasons for the apparent lack of efficacy of routine iron supplementation in reducing the risks of preterm and other adverse pregnancy outcomes are not clearly …
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Diversity of vaginal microbiota associated with bacterial vaginosis and the impact on pregnancy outcomes in HIV-infected and uninfected women.
The composition of vaginal microbiota in pregnancy is important as it may influence susceptibility to adverse pregnancy outcomes. Dysbiosis of the vaginal microbiota caused by the replacement of protective resident microorganisms such as Lactobacillus spp. by anaerobic bacteria is known as …
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The role of kisspeptin and its cognate receptor GPR54 in normal and abnormal placentation
Poor invasion of trophoblast cells in early pregnancy has been associated with preeclampsia and intrauterine growth restriction as well as other adverse pregnancy outcomes such as miscarriage, preterm birth and intrauterine death. Hypertensive disorders of pregnancy, including pre-eclampsia are one …
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Oral care during pregnancy: an educational intervention
… Interprofessional collaboration can help prevent adverse pregnancy outcomes related to poor oral health. This study was conducted to see if an educational module provided by a dental hygienist (DH) could increase the knowledge and confidence of physician assistant (PA) students with preventive …
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The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
… to establish other factors which may predict adverse pregnancy outcomes. Three hundred and one pregnant women were recruited from four different antenatal in the Western Cape, South Africa. The study conformed with the Declaration of Helsinki (2013). Maternal data was collected from a …
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Antiretroviral therapy and pregnancy outcome in HIV-infected women in the United Kingdom and Ireland
The aim of this thesis is to explore pregnancy and perinatal outcomes in diagnosed HIV-infected women receiving antiretroviral therapy (ART) in the UK (United Kingdom) and Ireland. Population-based surveillance data on HIV-infected pregnant women and their children is collected through the National …
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Correlation of Macroscopic and Microscopic Placental Lesions with Obstetric and Neonatal Outcomes in an unselected Population
… in the setting of maternal health problems and adverse fetal/neonatal outcomes. In specific clinicopathological circumstances - eg vascular lesions in the growth restricted fetus – correlation does exist between the placental lesion and the clinical event. Relationships between “lower grade” …
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