Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 80 for “"Adverse event"”.
-
Assessing the Sensitivity of the Canadian Adverse Event Following Immunization Surveillance System ( CAEFISS)
… population, careful monitoring of their adverse events is necessary. Canada has a national surveillance system that collects reports on adverse events that may be associated with vaccine administration. Sensitivity is one of the tools used with surveillance systems to study the extent and …
-
The reliability and validity of adverse-event measures of the quality of health care
… and new statutory and legal mechanisms. Adverse events in healthcare, which can be loosely defined as instances which indicate or may indicate that a patient has received poor quality care, offer an important opportunity for quality measurement and improvement. There is extensive evidence …
-
Adverse event registry analysis of an EMS system in a low resource setting: a descriptive study
… Hypothesis/problem Our study describes the adverse event registry of an emergency medical service system in a low resource setting over a six-year period. Methods The Western Cape Emergency Medical Services Adverse Event Registry were reviewed for the period 1 January 2010 to 31 December …
-
Associating adverse drug effects with protein targets by integrating adverse event, in vitro bioactivity, and pharmacokinetic data
Adverse drug effects are unintended and undesirable effects of medicines, causing attrition of molecules in drug development and harm to patients. To anticipate potential adverse effects early, drug candidates are commonly screened for pharmacological activity against a panel of protein targets. …
-
Detection of safety signals in randomised controlled trials
The occurrence, severity, and duration of patient adverse events are routinely recorded during randomised clinical trials. This data is used by a trial's Data Monitoring Committee to make decisions regarding the safety of a treatment and may lead to the alteration or discontinuation of a trial if …
-
Development of statistical methodologies and risk models to perform real-time safety monitoring in interventional cardiology
… been due to a small number of highly publicized adverse events, some of them in the domain of cardiac surgery and interventional cardiology. Phase three clinical trials for these devices are generally underpowered to detect rare adverse event rates, are performed in near-optimal environments, and …
-
Boundary Resilience: A New Approach to Analyzing Behavior in Complex Systems
… theory measures a system's internal reaction to adverse event, boundary resilience evaluates the impacts such an event may have on the surrounding environment. As the scope of this analysis is quite large, it was deemed appropriate to conduct a case study to determine the fundamental tenants of …
-
Just world violations prompt beliefs in karmic retribution
… crime against another person will experience an adverse event in response? In other words, how much do people believe in karmic retribution? Across three studies, we examined this question in the present research. Participants were randomly assigned to read about a sexual crime that varied in its …
-
The Impact of Complications and Errors on Surgeons
Background Adverse events within the context of healthcare can lead to significant physician psychological distress. Contemporary research links the experience of adverse events to the prevalence of burnout, depression, and impaired quality of life. Most of the prevailing literature focuses on the …
-
Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy
… and lactic acidosis (SHLA) are life-threatening events that are occurring at increasing incidence levels in South Africa. Globally, the rise in SHLA cases is closely correlated to the increased accessibility of anti retroviral (ARV) medication for human immunodeficiency virus (HIV). Although …
-
Incidence of adverse drug events in COVID-19 patients on anticoagulants: a pharmacovigilance study
… to detect, assess, understand, to ultimately prevent any adverse event associated with drugs. Today, with the world struggling to get the COVID-19 pandemic under control, it is important to look at how this disease is affecting different patient populations. A common complication associated with …
-
Optimization of N-(1-Adamantyl)-3-Aryl Acetamides as Novel Antimycobacterial Agents
… years and includes medications with serious adverse event profiles. Nontuberculous mycobacterial (NTM) infections are opportunistic infections in immunocompromised patients and those with underlying structural lung disease. Treatment for NTM infections necessitates greater than 1 year of …
-
Perceptions of clinical research coordinators about the quality of monitoring and major failings/concerns in the monitoring process
… Adequate monitoring of clinical trials can prevent the occurrence of significant problems, which may affect the entire process of bringing a new drug to market. The proper monitoring of clinical trials is a challenge. In spite of well established regulations and guidance, there remain many …
-
Evaluation of Food Effects on the Oral Pharmacokinetics of Rosuvastatin
… capacity of rosuvastatin. Since a common adverse event noted with statin therapy is muscle pain/damage associated with high circulating statin levels, our findings have the potential to serve as a novel and simple strategy for mitigating statin myopathy risk.
-
Examining Cognitive Vulnerability Models to Borderline Personality Features in a Sample of Emerging Adults
… mediator effects of maladaptive schemas on the adverse event-BPD symptom relationship. Four hundred and fifteen undergraduate students completed demographic information and three surveys online. Results indicated that both disconnection/rejection schemas and impaired limits schemas partially …
-
The PASS study: performance assessment system for success In residential aged care
… the impact of Quality Improvement Activities on adverse events in residential care for older people (nursing homes); and (ii) to explore the effectiveness of a Data Envelopment Analysis (DEA) quantity/quality model in providing additional information. Design: A cluster randomised controlled …
-
Establishing a patient safety pilot program in UCSF Medical Center – Benioff Children’s Hospital: Principles, System Analysis, and Initial Steps
… This project was created in response to an adverse event in which a safety concern was not appropriately escalated. The goal of the project is to create a mechanism for patients and families to independently escalate their safety concerns. The project utilized a multidisciplinary team to …
-
The Role of Social Support in Counselors' Responses to Client Adverse Events
… support, specifically after a professional adverse event. Professional adverse events are common given the nature of counseling work. For example, undesirable occurrences such as client suicide, attempted suicide, life threatening illnesses, accidents, overdose, or loss of a child are …
-
A Goal-Driven Methodology for Developing Health Care Quality Metrics
… validation process takes place in the context of adverse event management and incident reporting initiatives at a Canadian teaching hospital, where the HC-GQM provides a set of meaningful metrics and reports on the occurrence of adverse events and incidents to the stakeholders involved. The …
-
Measuring Resilient Aging in Different Populations of Older Adults
… aging literature in the past decade. The risk of adverse events increases linearly with age and therefore focusing on factors that help older adults recover can result in improvements in care and quality of life for older adults. There is still no consensus on how to operationalize resilience in …
Page 1 of 4