Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Adverse Outcome Pathways"”.
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Metals and polycyclic aromatic hydrocarbons in environmental matrices of the Fleet Lagoon, UK and toxicological investigations using the marine polychaete Hediste diversicolor.
… used within environmental monitoring to forecast adverse outcome pathways via the assessment of endpoints including those of cellular, molecular, behavioural, tissue, systemic and organism responses and alterations. However, research is primarily conducted upon bioaccumulation and adverse outcome …
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Integration of Data Quality, Kinetics and Mechanistic Modelling into Toxicological Assessment of Cosmetic Ingredients
… improving modelling performance and supporting Adverse Outcome Pathways (AOPs) with definitions of structural alerts and physico-chemical properties. Furthermore, there was a clear focus on the transparency of models, i.e. approaches using algorithmic feature selection, machine learning etc. …
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Using transcriptomic data to detect, understand, and treat injury in the context of drug toxicity and fibrotic disease
… treat a condition, but also how it can result in adverse effects so that safety risks can be mitigated earlier. How effects propagate from the molecular to the systems scale is, however, in many cases not fully clear, in particular for complex phenotypes which cannot be narrowed down to individual …