Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 22 for “"Adriamycin"”.
-
Effects of Ice Application on Alopecia Produced by Adriamycin
… thereby reducing the alopecia caused by the drug adriamycin. The use of cold is known as a vasoconstricting agent. It was thought that if vasconstriction could be maintained for the first few minutes following the injection of adriamycin, the incidence of alopecia could be reduced.</p> …
-
Comparison of two neoadjuvant chemotherapy in locally advanced breast cancer patients; Adriamycin and Docetaxel (AD) versus Adriamycin, Cyclophosphamide followed by Paclitaxel (AC-T)
… AND METHODS: We compared the women received adriamycin and docetaxel (AD) with adriamycin, cyclophosphamide followed by paclitaxel (AC-T) as neoadjuvant chemotherapy from 1 November 2005 to 31 September2011. The AD group was scheduled for 6 cycles of AD (50mg/m2 and 75mg/m2, respectively) in …
-
Melatonin's Protection against DNA Damage by the Iron (III)-Adriamycin Complex.
<p>Adriamycin is a first line cancer treatment drug for breast cancer and many soft tissue carcinomas. Adriamycin is a highly effective anti-cancer drug. It has a fused ring system that is planar, hydrophobic and electron rich. These features allow intercalation into DNA which, along with its …
-
Course of clinical response during primary systemic therapy with a dose-dense 4 cycles regime of adriamycin and docetaxel in patients with operable cancer of the breast
Background: <br>In contrast to adjuvant chemotherapy (AST), primary systemic therapy (PST) allows the observation of clinical response under treatment, serving as an in-vivo chemosensitivity test. One possibility to assess tumor response is the consideration and analysis of clinical parameters such …
-
ΣΥΓΚΡΙΤΙΚΗ ΜΕΛΕΤΗ ΧΗΜΕΙΟΑΝΟΣΟΘΕΡΑΠΕΙΑΣ ΚΑΙ ΧΗΜΕΙΟΘΕΡΑΠΕΙΑΣ ΣΕ ΠΡΟΧΩΡΗΜΕΝΟ ΚΑΡΚΙΝΟ ΟΥΡΟΔΟΧΟΥ ΚΥΣΤΕΩΣ
… THERAPY THAT IS 5 FLUOROURACIL 12 MG/KGR AND ADRIAMYCIN 50 MG/M2 IN ROTATING EVERY 3 WEEKS AND LEVAMISOLE 50 MG X 3 PER OS ON CRITICAL PERIOD AT 11TH, 12TH A 13TH DAY OF THE COURSE. THE SECOND GROUP WAS TREATED BY 5 FLU AND ADRIAMYCIN IN THE SAME DOSE AND ROTATING AS THE FIRST GROUP. THE …
-
In vitro screening of crude extracts and pure metabolites obtained from marine invertebrates for the treatment of breast cancer
… concentrations of compounds in the presence of Adriamycin demonstrated that none of the compounds tested appeared to interfere with Pgp function. Results obtained using HBEC in primary culture showed a wide range of chemosensitivities for a given drug against tissue taken from different …
-
Metabólitos produzidos por Streptomyces spp. com atividade antitumoral.
… used in human and veterinary medicine. The adriamycin, idarubicin, daunorubicin, dactinomycin, retamycin, mitomycin C, antibiotics are commonly used to treat many types of cancers. These drugs must eradicate cancer cells, and the advantages of its use are to be compared with the …
-
Investigation of the molecular mechanisms underlying the invasive phenotype in a panel of lung cancer cell lines
… from a non-small cell lung carcinoma and its Adriamycin resistant variant DLKPA highly invasive were used in this study to evaluate the roles of differentially expressed mRNAs and microRNAs. We developed two targetable DLKP cell lines based on Cre-LoxP technology. These were generated by …
-
Ruolo delle cellule staminali mesenchimali in modelli cellulari e animali di nefropatia
… on podocytes ‘in vitro’ and ‘in vivo’ utilizing adriamycin (ADR) as a model of renal toxicity. The ‘in vivo’ experimental approach was carried out in male Sprague Dawley rats (overall 60 animals) treated with different ADR schemes to induce acute and chronic nephrosis. MSC were given a) …
-
Does hair curl variation influence the efficacy of scalp cooling in the prevention of chemotherapy-induced alopecia in breast cancer patients? A randomized controlled pilot study
… with breast cancer to receive chemotherapy (Adriamycin or Epirubicin and Cyclophosphamide followed by Paclitaxel) with or without scalp cooling. The main outcomes were percentage alopecia (Severity ALopecia Tool scored by 3 dermatologists) in straight versus curly hair and treatment retention …
-
Pathway Profiling Of Replicative And Induced Senescence
… 5-aza-2-deoxycytidine (a demethylating agent), Adriamycin (a chemotherapeutic drug), and H2O2 (an agent causing oxidative stress).</p> <p>MDAH041 cells, which are fibroblasts isolated from a patient with Li Fraumeni Syndrome, have heterozygous alleles of p53 and can therefore undergo natural …
-
Effect of Relaxation on Neuro-Immune Responses of Persons Undergoing Chemotherapy
… cancer and slated to undergo four cycles of Adriamycin/Cytoxan (AC) chemotherapy. Subjects were assigned to an experimental or a control group. The control group underwent chemotherapy according to the prescribed AC regimen. The experimental group underwent the same chemotherapy and a …
-
ΑΝΑΛΥΣΗ ΤΩΝ ΑΛΛΗΛΕΠΙΔΡΑΣΕΩΝ ΑΝΘΡΑΚΥΚΛΙΝΩΝ-ΣΙΔΗΡΟΠΟΡΦΥΡΙΝΩΝ ΣΤΟ ΑΙΜΟΠΟΙΗΤΙΚΟ ΣΥΣΤΗΜΑ
ADRIAMYCIN (ADR) AND DAUNOMYCIN (DAU) AUNOMYCIN (DAU) ARE TWO OF THE MOST WIDELY AND USED CHEMOTHERAPEUTIC AGENTS FOR TREATMENT OF VARIOUS NEOPLASMS. HOWEVER,THEIR USE IS LIMITED DUE TO THEIR BONE MARROW (MYELOSUPPRESSION) AND CARDIOVASCULAR TOXICITY. UNFORTUNATELY, IT HASN'T BEEN A UNIFIED THEORY …
-
COMPARATIVE PROTEOMICS STUDIES OF SOLUBLE NUCLEAR PROTEINS OF DRUG SUSCEPTIBLE AND RESISTANT HUMAN BREAST CANCER MCF-7 CELLS
… cell lines resistant to etoposide, mitoxantrone, adriamycin in the presence of verapamil by both gel comparisons and isotope labeling. Abundances of cytoskeleton proteins, such as cytokeratin 8, cytokeratin 19, septin 2, and alpha tropomyosin, are altered in common across the three resistant cell …
-
p38 MAPK Signalling in Endothelial Apoptosis
… drug doxorubicin. Doxorubicin (also called Adriamycin) is a widely used anthracycline against a broad range of tumours and has been shown to exert its antitumoural effect via directly targeting the tumour vasculature. However, endothelial apoptosis is also implicated in doxorubicin-mediated …
-
Temozolomide and Bevacizumab Therapy In Advanced Hemangiopericytoma/ Solitary Fibrous Tumor
… 23 patients with advanced HPC/SFT who received adriamycin-based, gemcitabine based, or paclitaxel chemotherapy as first- or second-line therapy, the overall RECIST response rate was 0%. Most patients achieved a brief duration of disease stabilization on chemotherapy, with median progression-free …
-
Telomerase Inhibition and Sensitization of Breast Tumor Cells
… cells with two mainstay chemotherapeutic agents, Adriamycin (AdR) and Taxol. The most effective telomerase inhibition strategies were synthetic siRNA and DN-hTERT, individually. After treatment with various concentrations of AdR or Taxol, breast cancer cells with inhibited telomerase grew …
-
Βιολογική εξέλιξη των επιφανειακών όγκων της ουροδόχου κύστεως
… had a similar influence. 8) Thiotepa and Adriamycin showed a similar efficacy, comparatively. They diminished (18-19%) the number of patients who recurrenced in three years and elongated (5-6 weeks) the Disease Free Interval (D.F.I.). There are indications that they influenced favorably …
-
Retrospective study at a single tertiary hospital in South Africa (Groote Schuur) on the treatment outcome in patients who underwent TransArterial Chemo-Embolization (TACE) for hepatocellular carcinoma
… benefit and hospital stays in TACE using Adriamycin with lipiodol, with no benefit demonstrated. The current study aims to compare the imaging and alpha fetoprotein (AFP) responses with previous international studies on treatment response. Objectives:. To elucidate imaging and AFP outcomes …
Page 1 of 2