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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Adrenals"”.
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The Effects of Actinomycin D and Acth on Circadian Steroidogenesis of Hamster Adrenals
Rhythmicity is predominant in nature. Sunrise is followed by sunset in a highly predictable periodic sequence. Living organisms are known to be influenced by such periodically occurring phenomena. De Mairan, as early as 1729, observed leaf movements of plants and found these variations to be …
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Identifying the mechanism critical for proliferation, apoptosis, and cell-cell interaction in the development of mouse adrenals and gonads
Adrenal, testis, and ovary are steroidogenic organs derived from a common primordium that consists of Steroidogenic factor 1 (SF1)-positive precursor cells. SF1 not only defines the steroidogenic lineages in these organs, but also controls their differentiation. In this thesis project, I used …
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Regulation of cortisol secretion in humans: relation to vasopressin action at the adrenals in macronodular and micronodular adrenocortical tumours; and well-being in Addison’s Disease.
The hypothalamic-pituitary-adrenal (HPA) axis exhibits tight physiological regulation on a circadian and ultradian basis in humans. Key central regulators include the peptides corticotrophin-releasing hormone (CRH) and arginine vasopressin (VP), acting at the pituitary, and at peripheral structures …
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Comparative morphology of the adrenal glands of wild and domesticated mice and the effect of captivity on adrenal structure.
… or represent a generalization in nature, the adrenals were examined in other species of rodents. For this purpose the adrenals of white-feeted mice(Peromyscus-leucopus noveboracensis), house mice(Mus musculus domesticus), and Garworth Farms - W albino mice(Mus musculus domesticus) were …
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An Exploratory Study of the Systemic Effects of Lead, Trichloroethylene, and a Mixture of Lead and Trichloroethylene Provided Concurrently by Oral Gavage to Male Rats
… in the testis, spleen, heart, liver, kidney-adrenals, and brain. Results indicated that each compound was toxic individually, and that the combination of the two neurotoxicants provided conflicting indications of both reduced and additive toxicity. The toxicity of lead carbonate caused the …
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Συσχέτιση ιστολογικών, βιοχημικών και αιματολογικών ευρημάτων μετά από χορήγηση LPS P. aeruginosa σε επίμυες wistar: Πειραματική μελέτη
… were: heart, lung, liver, spleen, kidneys, adrenals and eyes. In addition the distribution of the three LPSs in the liver was studied with immunochemistry and sections of liver tissue were examined in ultrastractural microscope. Bone marrow was aspirated as well as collection of whole blood …
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Modelling altered Glucocorticoid Sensitivity: From HPA axis to metabolic abnormalities in mice and humans
… tissue, 30% in liver, 56% in muscle and 67% in adrenals. X-gal staining of GR+/- brain sections showed that GR-beta gal is present throughout, mirroring GR mRNA expression. Adult GR+/- mice had larger adrenals, higher evening plasma corticosterone levels and greater corticosterone responses …
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Examination of the Effects of Pinealectomy upon Adrenal Structure in the White Rat
… days and reared in total darkness possessed adrenals which were slightly lighter than those of light/dark reared animals. This difference became significant when adrenal diameters were compared. Pinealectomy did not induce a consistently significant alteration in rates of growth, although …
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Effect of Chronic Ethanol Consumption on Vitamin a Metabolism (beta-Carotene, Rats)
… tissue vitamin A accumulation, primarily in the adrenals and lungs, and increased recovery of label from vitamin A in nonhepatic tissues occurred in ethanol-fed rats. In contrast, kidney vitamin A levels were either lower or unchanged in ethanol-fed rats. Decreased hepatic vitamin A levels may be …
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The role of basic fibroblast growth factor in the compensatory adrenal growth response
… 18.6, 21 and 22.5 kD were identified in rat adrenals by SDS-PAGE and Western blot. Basic FGF was localized immunocytochemically in cells of the glomerulosa and the medulla. Basic FGF stimulated a 68-80% increase in the rate of DNA synthesis in adrenal capsule-glomerulosa preps in vitro. …
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Investigating the maintenance of the mouse definitive adrenal cortex
… integration. Indeed, mosaicism of the transgenic adrenals was demonstrated by RT-PCR and immunostaining, which also revealed that the exogenous EGFP expression faithfully recapitulated the endogenous Cyp11b1 in adrenals. Although it is assumed that expression of Cyp11b2 and Cyp11b1 are mutually …
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Transcriptome analysis of the hypothalamic-pituitary-adrenal axis in the experimentally domesticated fox
… related to exocytosis and cellular signaling; adrenals analysis identified differences in similar pathways, in addition to genes related to fatty acid and cholesterol synthesis. Variant analysis also implicated cell signaling and exocytosis, as well as ion transport and DNA damage repair. These …
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Neonatal septal lesions and early malnutrition: interactive effects on physiology and behavior
… 8% protein animals had heavier brains and adrenals relative to their body weight. The higher adrenal weight/body weight ratio was more pronounced in males, particularly those without neonatal septal lesions.</p> <p>Subsequent to the 7-week dietary recovery period on Purina chow rats …
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Effects of a polychlorinated biphenyl in mice caged at different densities and fed at different nutritional levels
… in the mobilization of corticosteroids from the adrenals of white mice. These effects were intensified in white mice subjected simultaneously to either increased density or feed restriction. It was concluded that animals subjected to overcrowding or inanition are more susceptible to the …
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Role of two genes, CACNA1D and CADM1, with common or rare mutations in aldosterone producing adenomas of the adrenal.
… that CYP11B2 expression is reduced by 50% in the adrenals of CaV1.3 knockout mice. The discovery of mutations in CACNA1D led to a drug discovery challenge award from a pharmaceutical company in which high-throughput screening of CaV1.3-expressing cells was undertaken against the company's 1.8M …
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The cytology of adrenocortical regeneration in the rat and the effects of x-irradiation
… by the dorsal route under ether anesthesia. Both adrenals were bisected and immediately autotransplanted to pockets in the dorsal musculature. All animals were given one per cent saline drinking water for the entire experimental period and Purina Laboratory Chow was fed ad libitum. These animals …