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Showing 1 to 20 of 461 for “"Adjuvant"”.
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Adjuvant Chemoradiation Therapy in Gallbladder Cancer
… gastrointestinal malignancy. Indications for adjuvant chemoradiation therapy after surgical resection have not yet been determined. We aimed this study to elucidate the effectiveness of adjuvant chemoradiation therapy according to TNM stage for gallbladder cancer. Between March 2001 and March …
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Mechanism of Action of Freund's Complete Adjuvant
Made available in DSpace on 2014-12-09T22:30:16Z (GMT). No. of bitstreams: 1 6812101.pdf: 3377124 bytes, checksum: 90fef7c60484d5295e5b690e9d48c96f (MD5) Previous issue date: 1968
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Characterization of Alpha-Galactosylceramide As A Mucosal Adjuvant
Adjuvants are essential components of vaccine formulations that enhance adaptive immune responses to antigens, particularly for immunizations targeting the tolerogenic mucosal tissues, which are more biologically relevant for protective immunity against pathogens transmitted by the mucosal routes. …
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The Treatment of Solid Tumours with Complete Freund's Adjuvant
… potential cancer treatment, Complete Freund’s Adjuvant (CFA), which is injected intratumourally in an attempt to induce an anti-tumour immune response, leading to tumour regression. CFA has been used in research for decades, primarily to produce research antibodies. CFA is composed of …
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The Treatment of Solid Tumours with Complete Freund's Adjuvant
… potential cancer treatment, Complete Freund’s Adjuvant (CFA), which is injected intratumourally in an attempt to induce an anti-tumour immune response, leading to tumour regression. CFA has been used in research for decades, primarily to produce research antibodies. CFA is composed of …
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Physicochemical studies of a novel adjuvant and conjugate vaccines
… in the presence of the other antigens and adjuvant presents a challenge. Aluminium containing adjuvants have been the most widely used adjuvants in human vaccines. Aluminium hydroxide has been found to catalyse the hydrolysis of PRP when added to Hib conjugate vaccines. Although this can be …
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Curare as an adjuvant to general anesthesia in the dog
To view the abstract, please see the full text of the document.
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EVALUATION OF ALPHA-D-GLUCAN NANOPARTICLE AS A VACCINE ADJUVANT
… for delivery of vaccine antigens and as vaccine adjuvants is appealing because their size allows efficient uptake by dendritic cells and their biological properties can be tailored to the desired function. Here, we evaluated the potential of dendrimer-like α-D-glucan nanoparticles, derived from a …
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Sympathetic Nerve Modulation of Joint Pathology in Adjuvant-Induced Arthritis
… Adult rats were injected with complete Freund’s adjuvant. At 12 days post immunization, animals were randomly placed into a drug treatment group (SH1293, which interacts with - and ß2-ARs), an adjuvant arthritic group, or a control group. These animals were sacrificed at 14, 21, 28 and 126 days. …
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Cytokine-bearing Influenza Vaccine: Adjuvant Potential of Membrane-bound Immunomodulators
Influenza epidemics continue to cause morbidity and mortality within the human population despite widespread vaccination efforts. This, along with the ominous threat of an avian influenza pandemic (H5N1), demonstrates the need for a much improved, more sophisticated influenza vaccine. Our group has …
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Expression strategies for plant-based production of a vaccine adjuvant
… tends to be low and second, co-expression of an adjuvant may be required to facilitate an appropriate immune response. Ricin, a plant toxin that survives the human digestive process, has been proven to stimulate an immune response and could therefore serve as a suitable adjuvant. The long-term …
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Practice Patterns and Health Outcomes of Adjuvant Oxaliplatin Chemotherapy for Colorectal Cancer
INTRODUCTION: Oxaliplatin-containing adjuvant chemotherapy improves survival for stage III colon cancer. Yet it is not without harms, most commonly dose-dependent peripheral neuropathy. The 2018 International Duration Evaluation of Adjuvant Chemotherapy (IDEA) trial sought to determine the optimal …
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The Influence of Immunization Route On The Adjuvant Effect of Alpha-Galactosylceramide
<p>Potent vaccine formulations ideally include adjuvants to activate innate immune responses and enhance antigen-specific adaptive immunity. The synthetic glycolipid alpha-Galactosylceramide (α-GalCer) effectively activates the innate immune mediating NKT cells to produce cytokines and activate …
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Adjuvant Interactions with Lipid Membranes and Their Effect on Cellular Immune Responses
Adjuvants are commonly included in vaccines and have been invaluable in making them safer and more robust. Despite their prolific use, adjuvant mechanisms of action remain poorly understood. Many receptor-mediated mechanisms have been proposed for adjuvants, and many likely contribute to their …
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Does the Timing of Adjuvant Chemotherapy for Gastric Cancer Influence Patient Outcome?
PURPOSE: Although adjuvant chemotherapy is currently established as standard treatment in stage II/III gastric cancer, there is no report about the optimal timing of the initiation of chemotherapy. We investigated the effect of the interval between surgery and the start of chemotherapy on patient …
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Development of a Novel Vaccine Adjuvant and Delivery System for Cancer and Influenza
<p>Vaccines often require addition of adjuvants to boost the potency and longevity of antigen specific immune responses. At present, there is a scarcity of safe vaccine adjuvants and delivery systems that can stimulate both cellular (Th1) and humoral (Th2) immune response. Such adjuvants are …
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