Global ETD Search

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Showing 1 to 3 of 3 for “"Adenosine 2a Receptor"”.

  1. FAMIN in dendritic cells biochemically restrains T cell priming

    … hypoxanthine to inosine that acts on the T cell adenosine 2A receptor (A<sub>2A</sub>R). In summary, FAMIN is a multifunctional purine nucleoside enzyme enabling flux through purine interconversion pathways highly integrated with cytoplasmic and mitochondrial metabolism. In DCs, FAMIN acts as a …

    cambridge Repository record for FAMIN in dendritic cells biochemically restrains T cell priming (opens in a new tab)

  2. Neuromodulation and neural circuits underlying cognitive flexibility in the rat

    … 4, I found dissociable effects of D1 and D2 receptor antagonists during different stages of serial visual reversal learning when administered into the nucleus accumbens shell. In chapter 3, I used a recently developed valence-probe visual discrimination task to dissociate different components …

    cambridge Repository record for Neuromodulation and neural circuits underlying cognitive flexibility in the rat (opens in a new tab)

  3. Analysis of Adenosine 2a Receptors During the Immune Recognition of Foreign and Self-Antigens

    Purinergic receptors are attractive therapeutic targets that can regulate several facets of the immune system. This dissertation examines the role of purinergic G protein-coupled Adenosine 2a (A2aR) receptors in regulating adaptive immune responses during the primary response to vaccination and …

    umn Repository record for Analysis of Adenosine 2a Receptors During the Immune Recognition of Foreign and Self-Antigens (opens in a new tab)