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Showing 1 to 1 of 1 for “"Adenine base editor"”.

  1. GATA1 Occupancy Site Regulates Erythroid Cell Fitness through Pleiotropic Functions

    … to phenotype. In this study, we combined base editor-mediated perturbations of regulatory elements, CRISPR-mediated gene disruptions, epigenetic profiling, and chromatin organization data with hybrid deep learning models to quantitatively predict the functional consequences of mutations …

    tenn-hsc Repository record for GATA1 Occupancy Site Regulates Erythroid Cell Fitness through Pleiotropic Functions (opens in a new tab)