Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Adenine Nucleotides"”.
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Influx and Efflux of Adenine Nucleotides From Erythrocytes Regulate Oxygen Transport and Systemic Metabolism
… a previously unrecognized pathway of adenine nucleotide influx and efflux that modulates erythrocyte’s oxygen binding ability and controls systemic metabolism. Our studies show that the loss of AMPD3 and CD73, two important enzymes in regulating AMP levels intra- and extra-cellularly, …
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Studies of the NAD metabolism of Haemophilus influenzae
… is incapable of synthesis of pyridine nucleotides from the usual precursors. An externally directed nucleotide pyrophosphatase was extracted from the organism and purified 700-fold using ammonium sulfate precipitation, ion-exchange and affinity chromatography. The enzyme was determined …
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Metal-ions in biofluids-aluminium in-vitro studies
… of aluminium III of inorganic phosphates and adenine nucleotides have been determined at ionic strength. I = 0,15 and a temperature of 25°C using glass electrode potentiometry and computer modelling. The protonation sequence for tripolyphosphate has been determined using n.m.r. studies.
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Membrane reconstitution studies on the irreversibility of inactivation of sarcoplasmic reticulum of rabbit skeletal muscle
… sarcoplasmic reticulum to bind Ca²⁺ or adenine nucleotides tightly was investigated. The capacity to bind calcium tightly was decreased from 1.43 nmol Ca²⁺/mg protein in control to 0,96nmol Ca²⁺/mg protein in acid inactivated sarcoplasmic reticulum. Similarly, the capacity to bind …
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Functional characterisation of the human mitochondrial ATP-Mg/Pi carriers and their disease-causing variants
… carriers (APCs) catalyses the exchange of adenine nucleotides for phosphate across the mitochondrial inner membrane, which is regulated by calcium. They are responsible for modulating the adenine nucleotide pool in the mitochondrial matrix, and therefore have a pivotal role in meeting the …
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The effects of creatine supplementation on performance and metabolism during brief, intermittent, high-intensity exercise
… associated with decreased degradation of adenine nucleotides, reflected by lower plasma [NH3 +], and greater ATP turnover, caused by an increase pre-exercise PCr availability.
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Acetate Increases Brain Purine Metabolism And Glial Cell Culture Fatty Acid Content: Studies Investigating Glyceryl Triacetate's Therapeutic Mechanism Of Action
… the endogenous response to adenosine and adenine nucleotides. Lastly, studies testing the concentration-dependent effects of acetate on fatty acid, phospholipid, and cholesterol content showed that lower acetate concentrations increase fatty acid and cholesterol levels in BV2 cells. This …
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The effect of oral creatine supplementation on one hour cycling performance and metabolism
… differences were noted in the resting levels of adenine nucleotides in either group. Analyses of the plasma samples indicated no change in plasma lactate concentration, but a significant lowering of indicators of adenine nucleotide degradation including concentrations of plasma ammonia (p<0.05) …
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Targeting Mitochondrial ROS Production in Kidney Transplantation
… succinate accumulation and the depletion of adenine nucleotides, occur in grafts retrieved from both DBD and DCD donors, despite differences in their exposure to warm ischaemia. This may partly relate to difficulties in efficiently cooling organs and suggests grafts from both donor types may …
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Inhibitation of succinate oxidation in beef heart mitochrondria by derivatives of pyridine adenine dinucleotide
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Studies on the mechanism of action on antitumour imidazotetrazinones
… (O6-AGAT) and 3-methyladenine-DNA-glycosylase (3MAG) have been examined in a range of murine and human cell lines with differential sensitivity to temozolomide. All the cell lines were proficient in 3MAG despite there being 40-fold difference in sensitivity to …