Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Adaptor protein complex"”.
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An investigation of the function of adaptor protein complex 4 (AP-4)
… organelles. During vesicle trafficking, proteins are selectively sorted into membrane bound transport intermediates by vesicle adaptors, which include those of the highly conserved adaptor protein (AP) complex family. Each AP complex has a distinct subcellular localisation and functions …
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Novel Roles of PACS-1 Within the Nucleus and the Regulated Secretory Pathway
… homeostasis, and PACS-1 regulation of membrane protein trafficking within the regulated secretory pathway. First, our results establish PACS-1 motifs that regulate nuclear localization through the classical nuclear trafficking pathway. Moreover, we have identified a novel interaction between …
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Investigating the Biological Functions of the Protein Kinase WNK1 in the Regulation of Cytoskeletal Structures and Membrane Trafficking
… data suggested that dynein and its associated protein-dynactin, centrosomal protein of 70 and 170 kDa might be potential interactors mediating microtubule related phenotypes. Second, I examined WNK1 and membrane trafficking events. Depletion of WNK1 caused higher amount of epidermal growth …
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Actin-like filament A (AlfA) and AlfA-driven plasmid segregation
… the cytomotive AlfA filaments, the DNA-binding protein AlfB and the centromeric DNA sequence parN. We obtained a near-atomic resolution structure of an AlfA filament in the presence of AMP-PNP using cryo-electron microscopy (cryo-EM). We built an atomic model based on the electron density map …