Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Adaptive Laboratory Evolution"”.
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Adaptive Laboratory Evolution of Scenedesmus obliquus for Increased Carbohydrate Content and Biomass Productivity
… biomass productivity. This thesis explores two adaptive laboratory evolution strategies for improving <em>Scenedesmus obliquus</em>: single UV-mutagenesis and low light cultivation at a high dilution rate to produce cultigens with greater carbohydrate content and iterative UV-mutagenesis and …
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Metabolic engineering and adaptive laboratory evolution of yeasts to achieve efficient microbial cell factory
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
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Enhance heme biosynthesis in Saccharomyces cerevisiae
… production in Saccharomyces cerevisiae through Adaptive Laboratory Evolution (ALE) and Atmospheric and Room Temperature Plasma (ARTP) mutagenesis, complemented by strategic nutrient supplementation. Despite the theoretical promise of ALE and ARTP to induce beneficial mutations for augmented heme …
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Improving Bacterial Therapeutics and Diagnostics through Synthetic Biology
… tract that reduce EcN viability. We performed adaptive laboratory evolution on EcN to select for mutated populations with greater tolerance to pH and bile and we identified specific mutations that contribute to their enhanced viability in the presence of these chemical stressors. The developed …
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A Systematic Method for Enhanced Expression of Alcohol Dehydrogenases in Escherichia coli
… to the E. coli strains of interest via adaptive laboratory evolution; the final evolved strain provided a further 4.15-fold and 4.87-fold improvement to the soluble yield of the system for the two alcohol dehydrogenase models. The evolved expression strain, E. coli ALE strain ‘D9’, …
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Electrogenetic pathways in cyanobacteria
… unknown. This limits our understanding of the evolutionary history, biochemical mechanisms and physiological functions of electrochemical signal transduction in oxygen-evolving photosynthetic bacteria, hindering the development of optimised, solar-powered biotechnologies. Aiming to address …