NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 68 for “"Acyl-CoA"”.

  1. Charakterisierung von Acyl-CoA-Reduktasen

    Hellenbrand, JaninePublikationsserver der RWTH Aachen University2012

    cDNA sequences encoding fatty acyl-CoA reductases were cloned from the uropygial glands of barn owl (Tyto alba), domestic chicken (Gallus gallus domesticus) and domestic goose (Anser anser domesticus). Heterologous expression studies in Saccharomyces cerevisiae showed that they encode membrane …

    aachen Repository record

  2. Expression und Funktion der Acyl-CoA-Synthetase 5 in der humanen Epidermis

    Köster, Jan ChristophPublikationsserver der RWTH Aachen University2010

    … ceramides have been described in this context. Acyl-CoA is involved in different interconnected metabolic pathways, so enzymes with an acyl-CoA-synthetase activity are of great importance within skin lipid metabolism as shown by the example of FATP4 deficient mice. Up to now, there is only few …

    aachen Repository record

  3. Characterization and Heterologous Expression of Recombinant Drosophila melanogaster Fatty Acyl CoA Reductase

    Nowinski, MagdaUniversity of Nevada, Reno2012

    Insect genomes have multiple fatty acyl CoA reductases (FARs), which implies varying substrate and product profiles. However, very few of these FARs have been characterized. Expression of the FAR CG18031 from Drosophila melanogaster in Spodoptera frugiperda (Sf)9 cells will allow for functional …

    unr Repository record

  4. Determining biological roles of four unique Vernicia fordii acyl-CoA Binding Proteins

    Pastor, Steven

    … the knowledge of its processes. Four unique tung acyl-CoA binding proteins, VfACBP3a, VfACBP3b, VfACBP4, and VfACBP6 were identified and the genes encoding them were cloned and analyzed to determine their biological roles. The VfACBPs were observed to be similar to other organisms' ACBPs, …

    uno Repository record

  5. Assessing Nutrient Composition of Skimmed Human Milk for Treatment of Chylothorax and Very Long-Chain Acyl-CoA Dehydrogenase Deficiency Patients

    Cheng, Kristin2027

    <p>Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is an inherited autosomal recessive metabolic disorder of fatty acid oxidation, and chylothorax is a condition where chyle accumulates in the chest cavity; both conditions require fat restriction as a treatment. Human milk feeding is …

    chapman Repository record

  6. Cholesterinmetabolismus in Toxoplasma gondii : Klonierung und Nachweis der Funktion eines Acyl-CoA: Cholesterin Acyltransferase aehnlichen Enzyms - ein neuer Angriffspunkt fuer pharmakologische Intervention

    Quittnat, Friederike SusanneUniversität Würzburg

    Ich praesentiere hier die Klonierung und Funktion eines ACAT-aehnlichen Enzyms von Toxoplasma gondii (T. gondii), das lebensnotwendig fuer T. gondii zu sein scheint. Medikamente, die gegen die menschliche ACAT gerichtet sind, erhoehen in geringen Konzentrationen die ACAT-Aktivitaet von T. gondii. …

    wurz-thes Repository record

  7. Untersuchungen zum Fettsäuretransport durch zelluläre und peroxisomale Membranen

    Scharnewski, Michael2012

    … Arbeit sind wir der Frage nachgegangen, ob Acyl-CoA-Synthetasen am Fettsäuretransport in Saccharomyces cerevisiae beteiligt sind. In früheren Studien konnten wir zeigen, dass die kombinierte Deletion der Acyl-CoA-Synthetasen FAA1 und FAA4 in YB332 zu einem Fettsäuresekretions-Phänotyp führt, …

    goettingen Repository record

  8. The Epidemiology and Health System Impact of Medium-Chain Acyl-CoA Dehydrogenase Deficiency Among Affected Children and Those with False Positive Newborn Screening Results in Ontario, Canada

    Karaceper, Maria DUniversité d'Ottawa / University of Ottawa2014

    … and health system impact of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) in Ontario. Methods: Following a review of methods to estimating robust health event rates for small populations, this study described health services use among infants diagnosed with MCADD or received a …

    ottawa-retro Repository record

  9. Structural and mechanistic investigation towards the regulation of M.tb isocitrate lyase

    Kwai, Brooke X.C.ResearchSpace@Auckland2022

    … by lipid metabolite acetyl-coenzyme A (acetyl-CoA) and its structural analogues. The interactions between host and pathogen are important for M. tb as the bacteria may reside inside its human host for decades. Human macrophages produce itaconate as an antimicrobial metabolite. Previous studies …

    auckland-ms Repository record

  10. Fettsäuretransport in die peroxisomale Matrix von <i>Arabidopsis thaliana</i>

    Struß, Annett2012

    … cerevisiae eine aktivierte Fettsäure in Form von Acyl-CoA postuliert. Andererseits sind für die weitere Metabolisierung durch ß-Oxidation die beiden peroxisomalen Acyl-CoA-Synthetasen LACS6 bzw. LACS7 notwendig. Der Transport der mit CoA aktivierten Fettsäure in die Peroxisomen und die dennoch …

    goettingen Repository record

  11. Optimisation of trierucin content in oilseed rape

    Batra, NeeluPublikationsserver der RWTH Aachen University2005

    … have been undertaken. Co-expression of an 22:1-CoA specific lysophosphatidate acyltransferase gene with a ß-ketoacyl-CoA synthase (KCS) gene in developing seeds of HEAR plants resulted in the channeling of 22:1 into each position of the glycerol backbone but hardly improved the total 22:1 …

    aachen Repository record

  12. Interplay of DGAT1, PDAT1 and DGAT2 Enzymes in Plant Triacylglycerol Assembly

    Regmi, Anushobha2020

    <p>Acyl-CoA:diacylglycerol acyltransferase (DGAT) catalyzes the transesterification of fatty acid from acyl-CoA to diacylglycerol (DAG) forming triacylglycerol (TAG, a.k.a oils and fats). Most plants have at least two unrelated <em>DGAT</em> genes, <em>DGAT1</em> and <em>DGAT2.</em> Plants …

    usm Repository record

  13. A Role for ACSBG1 in Obesity-Accelerated Breast

    Maguire, Olivia

    … this pure cancer cell population identified the acyl-CoA synthetase, Acsbg1, as robustly upregulated in cancer cells isolated from tumors in obese compared to lean animals. Overexpression of Acsbg1 in tumor cells further enhanced tumor growth in an obesity-specific manner, which required intact …

    rockefeller Repository record

  14. Ein neuer Syntheseweg für wertvolle Fettsäuren in Saccharomyces cerevisiae und Arabidopsis thaliana

    Hoffmann, Mareike2012

    … die Umesterung von VLCPUFA-Vorstufen zwischen an CoA gebundenen und lipidgebundenen Formen beschränkt. Dieser ineffiziente Transportprozess hatte in früheren Arbeiten zur Akkumulation von Δ6-desaturierten Fettsäuren geführt, die für weitere Syntheseschritte dann nicht mehr zur Verfügung standen. …

    goettingen Repository record

  15. Characterization of ceramide synthases (Cers) in mammalian cells

    Park, HyejungGeorgia Institute of Technology2009

    … the respective Cer synthases (CerS) and fatty acyl-CoA elongases, as well as changes in the fatty acyl-CoA's of the cells. Therefore, it is clear that Cer subspecies change during embryogenesis, possibly for functionally important reasons. One CerS isoform, CerS2, was studied further because it …

    gatech Repository record

  16. Effects of carnitine on medium-chain fatty acid metabolism in newborn pigs

    van Kempen, Theo A.T.G.University of Illinois at Urbana-Champaign2011

    … we observed significant changes in free and acyl-carnitines in plasma as determined using a newly developed HPLC procedure which allows for quantification of individual carnitine esters. The most noticeably change was observed in propionyl-carnitine, which increased significantly (from 0 to …

    uiuc Repository record

  17. The Role of ACAT2 in the Initiation and Treatment of Atherosclerosis

    Melchior, John TrevvettWake Forest University2012

    Hepatic acyl coenzyme A:cholesterol acyltransferase 2 (ACAT2) synthesizes cholesteryl ester (CE) from free cholesterol and fatty acyl-CoA. ACAT2 is responsible for the packaging of cholesteryl oleate (CO) into VLDL secreted from the liver and studies have shown a relationship between both ACAT2 …

    wfu Repository record

  18. Construction of comparative and framework linkage maps for the identification of quantitative trait loci in cattle

    Beever, Jonathan EdwardUniversity of Illinois at Urbana-Champaign2011

    … identified in the bovine genes for medium chain acyl-CoA dehydrogenase (ACADM), liver/bone/kidney alkaline phosphatase (ALPL), amylase 1 (AMY1), antithrombin III (AT3), Gardner-Rasheed feline sarcoma (v-fgr) oncogene homolog (FGR), alpha-L-fucosidase 1 (FUCA 1), interleukin 10 (1L10), myogenin …

    uiuc Repository record

  19. The Role of Sleep in Memory Consolidation with an Induced Sleep-Like State in Drosophila AND The Role of Alpha-synuclein in Fatty Acid Metabolism

    Suzuki, Yasuko2016

    … a role in fatty acid metabolism and specifically acyl CoA synthesis, further studies that examine the interaction of alpha-synuclein with free fatty acids could provide a better understanding of the protein's normal function.</p><p>Method: We examined the interaction of alpha-synuclein with oleic …

    wustl Repository record

  20. Design, synthesis, and evaluation of bioactive molecules; Chiral polyvinylpyrrolidones supported Cu/Au nanoclusters catalyzed cyclization of 5-substituted nona-1,8-dien-5-ols

    Zhang, ManKansas State University2017

    … C analogs were designed as long chain fatty acyl-CoA synthetase (ACSL) inhibitors for attenuating ischemia and reperfusion (I/R) injury. Oxadiazole derivatives were designed as T-type calcium channel inhibitors, which have potential application in the treatment of seizure and epilepsy. …

    ksu Repository record

Page 1 of 4