Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Acute seizure."”.
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The effects of an acute flurothyl seizure on associative learning and memory.
Past studies that utilized the flurothyl model of seizure induction have demonstrated impairment of spatial learning and memory in both neonatal and adult rats. However, most studies focused on inducing several seizures and much later examining learning and memory. The impact of a single acute …
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Rapid review of drug management for paediatric seizure termination in the emergency setting
Prolonged seizures are a medical emergency and require immediate treatment to prevent complications. Benzodiazepines (BDZ's) are integral to acute seizure management. The most commonly used BDZs are Lorazepam, Diazepam and Midazolam. Lorazepam is often perceived as the superior choice but recent …
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Anticonvulsant effects of PPAR-gamma activation in an in vitro model of seizure
… brain injury. Previous in vivo experiments using acute seizure models and preliminary studies in our laboratory using chronic seizure models suggest PPARγ agonists have anticonvulsant efficacy. These results, however, need to be replicated at a more concentrated level to understand tissue-specific …
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Development and Characterization of Pre-Clinical Epilepsy Models to Evaluate Potential Anti-Seizure Targets.
… obstacles. First, we have developed a model for seizure kindling using inhaled chemo-convulsant flurothyl that can be rapidly developed and is appropriate to use in research for epileptogenesis as well as screening for potential disease modifying theories. Next, we have pharmacologically …
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Neuromodulation by endogenous Interlukin-1β in hippocampus of the murine brain: Regulation of neuronal excitation
… further suggests that IL-1β regulates the innate seizure threshold, which arguably is a reflection of the homeostatic balance between excitation and inhibition (E/I) in the brain. Recognizing that the IL-1β signaling receptor, Interleukin 1 Receptor 1 (IL-1R1), is highly concentrated on granule …