Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 23 for “"Acute phase proteins"”.
-
Analytical validation and evaluation of the effects of intramuscular injections on acute phase proteins in horses
Acute phase protein (APP) measurement can be used to characterize and detect inflammation, as well as monitor response to therapy. Intramuscular (IM) injections often result in local swelling and inflammation, which may lead to increased plasma concentrations of APP. The first objective of this …
-
Characterisation of physiological and immune-related biomarkers of weaning stress in beef cattle
… interferon-gamma and increased concentrations of acute phase proteins compared with deferring housing for 35 days post weaning. In cows, transitory neutrophilia (increase in neutrophil number) and lymphopenia (decrease in lymphocyte number), reduced interferon-γ production, and increased …
-
Functional Significance of Glycoprotein Clearance by the Asialoglycoprotein Receptor and the Mannose/GalNAc-4-SO4 Receptor
… receptor: ASGR) is capable of clearing glycoproteins bearing terminal Siaalpha2,6GalNAc as well as ones bearing terminal Gal/ GalNAc and that the Mannose/GalNAc-4-SO4 receptor: MR) is capable of clearing glycoproteins bearing terminal GalNAc-4-SO4. I am taking a genetic approach identifying …
-
Immunoproteome of anti-TB drug associated DRESS in HIV TB co-infection
… We hypothesize that differentially regulated proteins would be found interindividually and with disease evolution that may provide a mechanistic understanding of DRESS underlying pathways. Participants and Methods: HIV cases with DRESS (probable or definite) and confirmed reactions to either …
-
SERUM AMYLOID A IN RUMINANTS: DIAGNOSTIC VALUE AND FOOD CONTAMINATION ASSESSMENT
… in this thesis were to investigate the bovine acute phase protein Serum Amyloid A, focussing on its value as safety marker in farm animals. SAA can be considered as a natural anti-inflammatory and immunomodulatory agent and local expression of SAA, at the site of the initial acute phase …
-
Effect of Severe Burn Injury on Body Composition and Muscle Metabolism in Pediatric Patients
… necessary for wound healing and production of acute phase proteins. However, there is a paucity of data concerning acute body composition changes in response to burn trauma, or factors that influence burn-induced muscle wasting. The objectives of this dissertation are 1) to quantify the extent …
-
The effect of a dietary phase 2 protein inducer on inflammatory parameters in blood and liver of spontaneously hypertensive stroke prone rats
… of oxidative stress is the inflammatory acute phase protein response. Oxidative stress and its accompanied inflammation can be reduced via phase 2 enzyme induction. Broccoli sprouts, a rich source of phase 2 enzyme inducers such as isothiocyanates, can be incorporated into the diet to …
-
Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
… effect, including downregulation of acute-phase proteins and inflammatory mediators. Mice receiving açai displayed an upregulation of steatosis markers and genes related to lipid synthesis, in line with the exacerbation of high-fat-induced fatty liver in these mice. The HELP-tagging …
-
The plasma protein fetuin: common structural features of the mammalian fetuin family
… analysis by Dr. D.L. Christie of the glycoproteins purified from plasma. During this project it was reported that the protein encoded kyf rat clone pp(# [Auberger et ai., (1989), Cell 58, 631-640] showed strong homology to bovine fetuin and human ag-HS glycoprotein. Further analysis, …
-
Investigating the effect of yeast and mineral dietary supplements during the periparturient period on the production, physical health, and innate immune system of dairy cows
… needs of lactation production. This homeorhetic phase requires the coordination of numerous hormones and tissues to mobilize fat for energy, stabilize mineral fluctuations such as calcium, and adjust the rumen environment to the change in diet. This transition is also the cause of common early …
-
The effects of equine plasma transfusion on markers of inflammation in healthy neonatal foals
… interleukin-17 [IL-17]), and 3) changes in acute phase protein (fibrinogen [FIB] and serum amyloid A [SAA]) production. A total of 35 healthy, neonatal foals (mean ± SD age 34 ± 5 hours) were randomly allocated into one of two groups, and given either hyperimmune, fresh frozen plasma …
-
Evaluation of serum C-reactive protein levels as a predictor of outcome in puppies infected with parvovirus
… treatment and elect for euthanasia of their pet. Acute phase proteins (APP) are proteins that change in concentration by at least 25% in animals subjected to external or internal inflammatory challenges, such as infection, inflammation or surgical trauma. Increased concentrations are associated …
-
Investigations Into a Rationally Designed Modified Live Vaccine for Equine Strangles
… of phagocytes in fish injected with S. zoo while acute phase proteins and antimicrobial lectins were up-regulated in fish injected with S. equi.
-
The effects of dietary lipid and rumen protected Capsicum oleoresin on plasma glucose and insulin kinetics, and feed efficiency in finishing beef cattle
… circulating blood metabolites and acute phase proteins, and insulin sensitivity in response to an intravenous glucose tolerance test. In the first study, the experimental design was a 22+1 factorial arrangement including: no additive (control; CON); a low or high dose of rumen …
-
The role of Serum Amyloid A1(SAA1) in coronary artery disease
… (SAA1) and serum amyloid A2 (SAA2) (A-SAA) are acute-phase proteins (APPs); the concentration of A-SAA can increase by 500-1000 fold during an acute systemic inflammation (Malle et al. 1993). The predominant form of A-SAA in plasma is reported to be SAA1 (Yamada et al. 1999). A-SAA has …
-
Effects of Lipopolysaccharide Induced Inflammatory Response on Early Embryo Survival in Ewes
… (TNF-&agr;), to induce an innate immune system acute phase response (APR). The induction of the APR and its reactant molecules, such as TNF-&agr; and acute phase proteins (APP), haptoglobin (Hp) and serum amyloid A (SAA), were initiated to study their effects on embryonic loss. In addition, ewes …
-
Welfare issues in Italian heavy pig production
… increase the risk of tail lesions, the level of acute phase proteins (i.e. blood markers of inflammation), or impair the health status (mortality, lung and gastric lesions) over the 30 weeks of fattening. Small amounts of straw (70 g/day per pig) increased the motivation for pigs to explore the …
-
An investigation of liver blood flow in systemic inflammation
… on the liver hepatocytes causing them to produce proteins. Plasma proteins that change in concentration with inflammation are named acute-phase proteins and the most clinically important of these is C-Reactive Protein. It is usually found in the plasma at concentrations of 3mg/l or less and values …
-
THE OMEGA-6: OMEGA-3 FATTY ACID RATIO IN SWINE NUTRITION: LONG-TERM EFFECTS ON PERFORMANCE, MILK FATTY ACID PROFILES, OXIDATIVE STATUS, AND PROTEOMES
… LR diet altered the plasma levels of several acute phase proteins (APPs) such as HP, SERPINA1, and APCS that might be involved in protective mechanisms against accelerated stresses and, in particular, oxidative stress at later stages of gestation and lactation. Furthermore, significant shifts …
-
The influence of a dietary supplement (NDS Baseline Probiotic) on the gastrointestinal quality and physical performance of endurance runners
… cultures), and to determine systemic release of acute-phase proteins (C3c, C4 and hsCRP in EDTA-plasma) and immunoglobulins (IgG, IgA and IgM in EDTA-plasma) and to measure gut permeability (urinary lactulose and rhamnose excretion; dosage: 5g lactulose and 0,5g rhamnose) before and after …
Page 1 of 2