Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 195 for “"Acute phase"”.
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Analytical validation and evaluation of the effects of intramuscular injections on acute phase proteins in horses
Acute phase protein (APP) measurement can be used to characterize and detect inflammation, as well as monitor response to therapy. Intramuscular (IM) injections often result in local swelling and inflammation, which may lead to increased plasma concentrations of APP. The first objective of this …
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Serum Lipocalin-2 (LCN-2) as a major acute phase protein under different pathological conditions in vivo and in vitro studies
… LCN-2-Genexpression mit bekannten großen Akut-Phase-Proteinen in der Leber in einem Ratten-und Mausmodell der Terpentin-Öl (TO) - induzierte sterilen Abszess. Darüber hinaus zeigt es, dass Serum Lipocalin-2 ist ein potentieller Biomarker von Strahlenschäden der Leber, aber nicht Lunge. Serum …
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Comparison of expression pattern and localization of iron transport proteins in rat liver, brain and spleen during acute phase response:invivo and invitro studies
Akute-Phase ist klinisch durch homöostatische Veränderungen wie Schläfrigkeit, adinamia, Fieber, Muskelschwäche und Leukozytose gekennzeichnet. Dramatische Veränderungen im Eisenstoffwechsel unter Akute-Phase-Bedingungen beobachtet. Unter den Bedingungen induzieren nicht-hepatischen Gewebeschäden, …
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SERUM AMYLOID A IN RUMINANTS: DIAGNOSTIC VALUE AND FOOD CONTAMINATION ASSESSMENT
… in this thesis were to investigate the bovine acute phase protein Serum Amyloid A, focussing on its value as safety marker in farm animals. SAA can be considered as a natural anti-inflammatory and immunomodulatory agent and local expression of SAA, at the site of the initial acute phase …
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ΠΡΩΤΕΙΝΕΣ ΟΞΕΙΑΣ ΦΑΣΕΩΣ ΣΕ ΕΜΦΡΑΓΜΑΤΑ, ΕΓΧΕΙΡΗΣΕΙΣ ΚΑΙ ΛΟΙΜΩΞΕΙΣ
FIVE ACUTE-PHASE REACTANT PROTEINS CRP HAPTOGLOBIN, A1 ANTITRYPSIN, A2 MACROGLOBULIN, AND A1 ACID GLYCOPROTEIN WERE STUDIED AFTER MYOCARDIAL INFARCTION, SURGERY AND VARIOUS INFECTIONS. IN SUMMARY CRP WAS CONSISTENTLY THE MST SENSITIVEOF FIVE ACUTE-PHASE REACTANT PROTEINS AND IS THEREFORE …
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MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN:LONGITUDINAL BODY COMPOSITION ASSESSMENT, INFLAMMATORY MARKERS, AND FATTY ACIDS PROFILE
… was to assess the risk of malnutrition in the acute phase and body composition over time in a cohort of children diagnosed with MIS-C. For all the recruited children, inflammatory markers, metabolic parameters, and fatty acid levels were assessed both in the acute phase and six months after …
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The effect of a dietary phase 2 protein inducer on inflammatory parameters in blood and liver of spontaneously hypertensive stroke prone rats
… of oxidative stress is the inflammatory acute phase protein response. Oxidative stress and its accompanied inflammation can be reduced via phase 2 enzyme induction. Broccoli sprouts, a rich source of phase 2 enzyme inducers such as isothiocyanates, can be incorporated into the diet to …
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Der Transkriptionsfaktor FKHR interagiert mit STAT-Faktoren und verstärkt die IL-6-Signaltransduktion
… but on the other hand reduce the synthesis of acute phase proteins in hepatocytes. This thesis will give a possible reason for this observation. An important pathway of signal transduction of growth factors depends on the activation of PI3 kinase and the ProteinkinaseB (PkB). Within the cell …
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Regulation of suppressor of cytokine signalling 3 expression by the pro-inflammatory cytokine (IL-1beta) in vitro and inflammatory stimuli in vivo
… of the organism. IL-6-induced expression of acute phase protein genes in the liver is tightly regulated through both IL-6-induced feedback inhibitors and the activity of pro-inflammatory cytokines such as tumor necrosis factor alpha and interleukin-1beta. In previous studies mechanisms of how …
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Early Maladaptive Cognitive Schema as a Predictor of Post-Stroke Depression
… to identify EMS as covariates for post-stroke acute and chronic phase depression, as well as the identification of acute phase EMS as predictors of chronic phase depression. Additional variables of health locus of control, social support and level of disability, among others, were also explored …
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Immunoproteome of anti-TB drug associated DRESS in HIV TB co-infection
… disease states and drug rechallenge reactions. Acute phase proteins and immunoglobulin kappa variable chains dominate the serum proteome of acute DRESS in TB/HIV co-infected patients, with CRP having the highest fold change (q = 2.5) in acute versus early recovery samples. LRG and L-Selectin (q …
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The Role of NLPR3 Inflammasome in Response to Thermal Injury and Sepsis
Although the induction of acute-phase inflammation after burn injury is essential, if prolonged it can induce increased risk of infection and sepsis. The NLRP3 inflammasome has established itself as an integral mediator of the acute phase response, however there is a current lack of understanding …
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Functional Significance of Glycoprotein Clearance by the Asialoglycoprotein Receptor and the Mannose/GalNAc-4-SO4 Receptor
… Gal or GalNAc are cleared by the ASGR. Many are acute phase proteins and we propose that the ASGR helps regulate their relative concentrations in vivo and enhances their increase during the acute phase response. LH bears terminal GalNAc-4-SO4 and the half life of LH is increased in MR-/- mice …
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Electrical and Optogenetic Stimulation of Sympathetic Neurons to Stabilize Blood Pressure after Acute Spinal Cord Injury
… motor disability and autonomic dysfunction. Acute blood pressure instability is associated with poor long term neurological recovery. Despite current clinical standards of care, blood pressure instability still occurs in the acute phase, and the in-hospital mortality of patients with acute …
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Factors affecting severity of injury in allergic renal disease
… second group of experiments, the induction of an acute phase response in rabbits by the subcutaneous injection of a local irritant was studied. It was characterised by changes in C-reactive protein (CRP), the third component of complement (C3), fibrinogen and polymorphonuclear leucocytes (PMN' s), …
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LncRNA Nostrill Facilitates Neuronal Antiviral Responses by Promoting NFkB-Mediated Irf7 Transcription
… resistant and susceptible to the chronic IDD phase of the infection. Few studies have investigated the mechanisms of antiviral gene expression in TMEV-IDD resistant and susceptible mice during the acute phase of infection. Differences in lncRNA expression during the acute phase, when …
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Modulation der IL-6-abhängigen Signaltransduktion durch die Protein-Tyrosinphosphatase SHP2
… STAT3 and STAT1 activation as well as enhanced acute-phase protein gene induction. Further reporter-gene-assays with a dominant negative SHP2 also show a greater inducibility of the examined promotors. Therefore, not only SHP2 itself, also its enzyme activity plays an important role in …
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