Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"Acute inflammation"”.
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Preeclampsia: The Roles of Acute Inflammation and Intrauterine Stress
<p>Preeclampsia (PE) is a severe, acute disease of pregnancy affecting approximately 8% of pregnant women after week 20 of gestation. PE is characterized by hypertension and renal damage reflected by proteinuria and has significant morbidity to both mother and fetus. Maternal symptoms range from …
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ROLE OF HYDROCORTISONE 21-HEMISUCCINATE DURING CARRAGEENAN-INDUCED ACUTE INFLAMMATION
… effects of hydrocortisone 21-hemisuccinate on acute inflammation induced by carrageenan. Intravenous injection of hydrocortisone 21-hemisuccinate resulted in a significant drop in circulating blood leucocytes, with a parallel decrease in the adhesiveness of these cells. Such observations may …
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Regulation of Hepatic Drug Transporters Expression in Mice During Acute Inflammation
Inflammation generated by many disease conditions is known to alter the expression and activity of several hepatic ABC and SLC transporters and drug-metabolizing enzymes. These pronounced changes in hepatic transporters contribute to altered drug disposition; therefore, understanding the molecular …
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Expression of leukocyte-endothelial adhesion molecules during acute inflammation in the lung
… is a critical step in the response of PMNsto inflammation. In the systemic circulation, the leukocyte adhesion molecule, L-selectin, facilitates PMN adhesion to inflamed endothelium while CD11/CD18 is required for PMN emigration into extravascular tissues. An inducible endothelial ligand for …
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Protective effect of dietary antioxidants and plant extracts on acute inflammation and hepatotoxicity in vitro
… cancer, diabetes, atherosclerosis, cataract and acute and chronic neurological disorders. Inflammation, the response of the host toward any infection or injury, plays a central role in the development of many chronic diseases. Several evidences demonstrated the rise of different types of cancer …
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MEDIATORS OF ACUTE INFLAMMATION AND THEIR ROLES IN MODULATING IN VI3^ LEUKOCYTE INFILTRATION AND PATHOBIOLOGIC ACTIVITY IN THE CONJUNCTIVA
… importance of these putative meditors during acute inflammation remains unclear. The present study investigated the roles of several candidate mediators within the context of Type I allergic conjunctival leukocyte infiltration and pathobiologic activity in the guinea pig. Histamine and the …
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The biogenesis of erythropoietin during inflammation
… response in experimental models of acute and chronic inflammation was appropriate for the associated anaemia. Macrophage-conditioned medium, interleukin-1β, interleukin-6, tumour necrosis factor-α, and neopterin were assayed for inhibition of erythropoietin synthesis by HepG2 cells …
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ΠΡΟΣΔΙΟΡΙΣΜΟΣ ΤΗΣ Α-ΑΜΥΛΑΣΗΣ ΣΤΗΝ ΠΑΡΩΤΙΔΑ ΛΕΥΚΩΝ ΕΠΙΜΥΩΝ ΜΕ ΠΕΙΡΑΜΑΤΙΚΗ ΟΞΕΙΑ ΠΑΓΚΡΕΑΤΙΤΙΔΑ
… GLAND AND THE CHANGES OF ITS VALUES DURING ACUTE INFLAMMATION OF THE PANCREAS (ACUTE PANCREATITIS). THE RESULTSWERE COMPARED WITH THOSE OF PREVIOUS STUDIES AND THE CORRELATION OF SECRETORY ACTIVITY THAT EXISTS BETWEEN THE PAROTID GLAND AND THE PANCREAS WAS DISCUSSED.
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Epigenomic and Transcriptomic Changes in the Onset of Disease
… diseases and illnesses: breast cancer, chronic inflammation, and mental illness. We profiled the epigenome of breast tissue from healthy women with the BRCA1 mutation to understand how the mutation may facilitate eventual breast cancer. Epigenomic changes in breast cells suggest that cells in …
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Toxic Effects of an Anionic Detergent on the Gills of Trout
… death is associated with lysosome formation. Acute inflammation of the gill tissue, extensive detachment of the epithelium and collapse of the pillar cell system occur. At concentrations above about 120 mg/1, very rapid lysis of cells results in the complete disruption of cellular and tissue …
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Epithelial Memory of Resolved Inflammation Limits Tissue Damage While Promoting Pancreatic Tumorigenesis
<p>Inflammation is a major risk factor for pancreatic ductal adenocarcinoma. When occurring in the context of pancreatitis, mutations of KRAS accelerate tumor development. We discovered that long after its complete resolution, a transient inflammatory event primes pancreatic epithelial cells to …
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Epigenetic Memory of Mouse Intestinal Inflammation
… regulation. Here, I show that in response to acute inflammation, chromatin in intestinal stem cells has increased accessibility around specific loci and that this state is maintained in some regions even after the epithelium has recovered from damage, suggesting the possibility of memory. Such …
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Measuring the Changes in Tumor Necrosis Factor-Alpha (TNF-α) from Secretory Populations of U937 Monocytic Cells during Differentiation.
… produced primarily by macrophages during acute inflammation. In this study we examined the differential effect of retinoic acid (RA) and phorbol 12-myristate 13-acetate (PMA) on the induction of TNF-α secretion from U937 monocytic cell populations by using the reverse hemolytic plaque …
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How the Outside Gets in: Linking Social and Physical Environments with Physiology and Body Size in Wild Baboons
… adversity is associated with elevated baseline inflammation as well as heightened acute inflammation in adulthood. To our knowledge, these predictions have only been tested in humans. Using serum samples collected from 89 baboons via brief anaesthetization, we measured several biomarkers of …
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Heterogeneity, Origins, and Role of Omental Macrophages in Health and Early Tumor Seeding
… foreign substances in the host to initiate acute inflammation, however prolonged signaling can lead to pathogenic conditions relating to cancer and neurodegenerative diseases. Pharmaceutical drugs are being developed to target TRM, however studies are needed to understand the role of each …
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Developing a vector for expressing serratiopeptidase in Lactococcus lactis
<p>Chronic inflammation stems from the inability of the body to resolve acute inflammation. Chronic inflammation is a growing health concern, as nearly 60% of Americans reported coping with at least one chronic condition (as of 2014). On a world scale, three fifths of deaths result from a chronic …
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NAD+-DEPENDENT SIRT1 REPROGRAMS CD11C+ DENDRITIC CELLS AND CD4+ T CELLS TO CONTROL IMMUNE POLARITY DURING SEPSIS
… of immune response polarity during sepsis and acute inflammation. Skewing of the polarity can lead to immunometabolic dysfunction, organ failure, and death from sepsis. Sirtuins are known regulators of immunity and have been shown to play a pivotal role in regulating innate immune responses. …
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Evaluation of the Harmonic Scalpel for Laparoscopic Bilateral Ovariectomy in Standing Horses
… or adhesion formation. Mild to moderate acute inflammation, and scar formation with moderate chronic inflammation at the ovarian pedicle was found 3 and 30 days after surgery, respectively. Median depth of coagulation necrosis 3 days postoperatively was 2.87 mm. Conclusions - The Harmonic …
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Dietary effects on pig health
… evaluated whether dietary SDP moderates inflammation and ameliorates impairment of reproduction caused by lipopolysaccharide (LPS) using pregnant mice as a model for inflammation in sows. The SDP increased (P < 0.05) ADG (0.712 vs. 0.638 g/d) before the LPS challenge (gestation day (GD) 3 …
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