Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 88 for “"Acute Toxicity"”.
-
The acute toxicity of molybdenum to the bluegill
The ninety-six hour TLm value for molybdenum as sodium molybdate to bluegills was determined as 1320 ppm molybdenum in ion-free water.
-
Acute Toxicity and Sub-Lethal Effects of Non-Point Source Pollutants on Invertebrates
… solvents. This dissertation examines the acute toxicity and sub-lethal effects of diuron, CuPT, B(a)P, and styrene in the mud snail, Ilyanassa obsoleta, the American oyster, Crassostrea virginica, the sea urchin, Lytechinus variegatus, and/or the barnacle, Amphibalanus (= Balanus) …
-
Acute toxicity of ammonia and nitrite to Pacific White Shrimp (Litopenaeus vannamei) at low salinities
… are gaps in the literature pertaining to the toxicity of ammonia and nitrite to shrimp. This study was conducted to investigate the individual and combined effects of ammonia and nitrite on L. vannamei postlarvae (25-45 days old) at 10 ppt salinity, 28 C and a pH of 7.8. The independent …
-
Acute Toxicity of Ammonia and Copper to Mussel (Bivalvia: Unionidae) Glochidia Inside and Outside of Conglutinates
… spent free in the water. This study compares the toxicity of ammonia and copper to glochidia inside and outside of conglutinates. Two species were investigated, one with cohesive conglutinates (Pleurobema sintoxia) and one with sheathed conglutinates (Ptychobranchus occidentalis). Glochidia of …
-
Estimation of the acute toxicity and prediction of the metabolism site for organic molecules using GALAS methodology /
… presents GALAS models for the estimation of the acute toxicity towards two rodent species following different administration routes as well as for the prediction of CYP3A4 and CYP2D6 regioselectivity in the main metabolic reactions mediated by these enzymes (13 individual models in total). All …
-
Validation of laboratory versus field avoidance behavior of schooling fathead minnows to heavy metal blends relative to acute toxicity during long term exposure
… in a steep gradient laminar flow chamber. Toxicity of the metal blend was determined for laboratory and field, control and metals acclimated fish. Unexposed fish avoided very low levels of the blend (29 ug/L total metals). Fish exposed to low levels of the blend (49 ug/L total metals) for 3 …
-
Comparative Toxicity of Eight Model Substances to the Sediment Dwelling Invertebrates Lumbriculus variegatus and Chironomus riparius
Existing ecotoxicity data for chemicals vary to a high extent between the environmental compartments water and sediment, since the evaluation of contaminants has historically focused on water exposition. Many anthropogenic chemicals and waste materials, including toxic organic and inorganic …
-
UNDERSTANDING CONDITIONAL MODES OF ACTIONS IN CHEMICAL-INDUCED TOXICITY USING RULE MODELS
… shifting efforts toward alternative methods for toxicity assessment is essential. However, slow regulatory acceptance of new approaches is governed by knowledge gaps in toxicity modes of action. In this thesis, I describe these challenges and the use of in vitro screening as an alternative of …
-
Integrative Bioassessment of Acid Mine Drainage Impacts on the Upper Powell River Watershed, Southwestern Virginia
… conducted to investigate the nature of AMD ecotoxicity in the upper Powell River watershed. Emphasis was placed upon bioassessment methodologies and AMD impacts beyond the zone of pH depression. Major findings and processes developed included: 1) an Ecotoxicological Rating (ETR) system was …
-
The use of Chironomus riparius (Diptera: Chironomidae) in benthic toxicity tests and its response to selenium
… conducted to: 1. Develop a method for performing acute toxicity tests using Chironomus riparius. 2. Establish relationships between dry mass and selenium content, and between dry mass and selenium body burden. 3. Determine whether bioaccumulation or bioconcentration contributed more to the …
-
Database development and machine learning prediction of pharmaceutical agents
… libraries. The last part was devoted to an acute toxicity classification system based on statistical machine learning methods. Evaluation of acute toxicity is one of the big challenges faced by pharmaceutical companies and many administrative organizations now because acute toxicity study is …
-
Tolerance Determination of Certain Benthic Invertebrates as Indicators in River Water Quality Monitoring
… dissolved oxygen, pH and heavy metals. Acute toxicity studies on H. angustipennis demonstrated the toxic effect of copper and zinc under variable conditions of water hardness, and the bioconcentration of zinc was demonstrated by the use of radioisotopes. Additional experiments …
-
Negative phototaxis of mosquito larvae as a potential tool in the rapid biological monitoring of aquatic wastes (Diptera: Culicidae)
A little-known approach to toxicity testing--based on negative phototaxis of larval <u>Aedes aegypti</u>--was investigated as a contribution to the search for rapid methods applicable to the field of water pollution control. Zinc and copper were the toxicants tested. All tests were conducted with a …
-
The anticancer potential of CITme, a quinoline derivative
… CITme with regard to antitumour activity, toxicity and pharmacokinetics. In vitro screening for neoplastic cytotoxic effects using standard cell culture techniques revealed cytotoxic activity against HeLa, DU-145, MCF-7, Jurkat and CoLo 320 human derived cancer cell lines at low …
-
QSAR studies of surfactant toxicity to Daphnia magna.
… in this thesis describes the study of the acute toxicity of sulphonated esters (FAES) of general formula R-CH(S03"Na +)-C02-R' to Daphnia magna. Due to structural similarities of this class of anionic surfactant to linear alkylbenzene sulphonate (LAS), it was considered that the log P based …
-
Evaluating the emerging environmental risks of mycotoxins in freshwater ecosystems.
… a freshwater environmental risk assessment. The acute response was measured in various groups of freshwater organisms including macrophytes Lemna minor, microalgae Pseudokirchneriella subcapitata, rotifers Brachionus calyciflorus, insects Chironomus riparius (larvae), crustaceans Daphnia pulex …
-
Evaluation of Chelex 100 and Assessing the Impact of Fulvic Acid (NOM) on Copper Toxicity and Bioavailability to Americamysis bahia
… when either 12 or 24 mg/L NOM was present. Acute toxicity bioassays were performed with mysid shrimp (Americamysis bahia) to evaluate the toxic effects of copper in the presence of Suwannee River Fulvic Acid, which served as a source of NOM. Static or static renewal tests, based on EPA …
-
Toxicity of aliphatic amines on the embryos of zebrafish Danio rerio - experimental studies and QSAR
The toxicity of 36 aliphatic amines on the embryos of the zebrafish Danio rerio were investigated. The DarT (Danio rerio Toxicity assay) was used to determine the lethal concentrations within a 48 h static acute toxicity test. A QSAR (Quantitative Structure-Activity Relationship) was performed …
-
Investigating the cause(s) of benthic macroinvertebrate community impairment downstream of two Saskatchewan uranium operations
… that surface-water was the primary cause of acute toxicity to H. azteca. Results from the Rabbit Lake in-situ study also demonstrated that surface water as the primary cause of acute toxicity to H. azteca, although the relationship was not as strong. The cause of in-situ toxicity at Key Lake …
-
LIQUID PLASTICS AS A NEW ENVIRONMENTAL PROBLEM? AN INTEGRATED RISK ASSESSMENT OF POLYVINYL ALCOHOL, POLYETHYLENE GLYCOL, POLYVINYL PYRROLIDONE AND POLYACRYLIC ACID
… ecosystems. This study aimed to evaluate the ecotoxicity of four commonly used WSPs—polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), polyethylene glycol (PEG), and polyacrylic acid (PAA)—using the freshwater fish Danio rerio and the crustacean Daphnia magna as model organisms. The impacts …
Page 1 of 5