Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Activity score"”.
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The Effects of an Intra-Dialytic Exercise Program on Self-Efficacy and Physical Activity: A Pilot Study
Background: Levels of physical activity are significantly lower among individuals with end-stage renal disease (ESRD) compared to their healthy sedentary counterparts. Low levels of self-efficacy (SE) with respect to exercise may contribute to a sedentary lifestyle in the ESRD population. …
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NONCANONICAL PYROPTOSIS PROMOTES NONALCOHOLIC STEATOHEPATITIS VIA LIPID PEROXIDATION AND TRAINED IMMUNITY
… macrovesicular steatosis and total NAFLD Activity Score (NAS). High fat feeding promoted recruitment and activation of HMΦ in both Caspase-11 deficient (Casp11KO) and WT male mice, however, noncanonical pyroptosis (caspase-11 activity, surface Gasdermin-D, expression, liver IL-1β …
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Mitochondrial Uncouplers: Development as Therapeutics for Metabolic Diseases
… nutritional overabundance and decreased physical activity. Due to the significant population affected and economic burden placed on national healthcare systems, there is a demonstrated need for effective weight management therapeutics. Obesity presents clinically diverse phenotypes that increase a …
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Investigations on the physiotherapy management of people following first-time patellar dislocation
… to construct the Norwich Patellar Instability Score. Study 3: A pragmatic multi-centre randomised controlled trial was conducted to compare the prescription of a general quadriceps exercise and rehabilitation programme (n=15) to a VMO-specific exercise and rehabilitation regime (n=12). Whilst …
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Successful Aging with Illness
… was a linear combination of participants’ ageism score and community activity score, while controlling for gender and age. When considered together, the results from these three manuscripts suggest that successful aging can be experienced by older adults aging with illness. And that, among these …
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Computational modeling-based discovery of novel classes of anti-inflammatory drugs that target lanthionine synthetase C-like protein 2
… is also illustrated by the anti-inflammatory activity of novel LANCL2 ligands such as NSC61610 against inflammatory bowel disease in mice. This dissertation discusses the value of LANCL2 as a novel therapeutic target for the discovery and development of new classes of orally active drugs …
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Metabolism and Body Composition in Chronic Inflammatory Arthritis: Prevention and Intervention through Pharmaceutical and Physical Means
… (bioelectrical impedance), and disease activity [C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), disease activity score 28 (DAS28) and health assessment questionnaire (HAQ)]. 20 of the total 68 patients, about to start anti-TNFα therapy, underwent the exact same …
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Exercise & cardiopulmonary physiology in rheumatoid arthritis
… function tests (PFTs). To estimate the disease activity score (DAS28) ‐ C‐reactive protein (CRP) was used in people living with RA. Results: Study 1: The most preferred exercise routine characterised by a frequency of “2-3 times per week”, moderate intensity, lasting “about an hour’’, with …
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„Sport und Alltagsfähigkeit nach vorderer Kreuzbandplastik mittels den Semitendinosus- und Gracilissehnen versus der Patellarsehne“
… postoperativ mittels Scoring-Systemen, („IKDC-Score“, „Lysholm-Score“, „Tegner-Activity-Score“, „Schweiger-Score“), funktionellen Testmethoden („Single-legged-hop“ Test, isokinetischer Maximalkrafttest der Knieextensoren und –flexoren, Kraft der Knieinnenrotation, „kneeling" und „knee-walking" …
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THE ROLE OF BETA-KLOTHO PROTEIN IN NAFLD PATHOGENESIS
… 4 (FGFR4), mediates in the liver the hormonal activity of FGF19 and plays a central role in the regulation of lipid metabolism and in bile acids’ biosynthesis. Thus, a stable KLB full knock-out model in HepG2 hepatoma cells (KLB-/-) has been generated by using Crispr/Cas9 technology, with the …
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The epidemiology of hospital admissions in a general population: record linkage of hospital episode statistics to the European Prospective Investigation of Cancer (EPIC-Norfolk) cohort
… of alcohol, body mass index and physical activity and future hospital usage while the implications for clinical and public health planning, policy and practice are also considered. The thesis is based on the European Prospective Investigation of Cancer in Norfolk (EPIC-Norfolk), a …