Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Active DNA demethylation"”.
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Regulation of Active DNA Demethylation and its Role in Fertility in Arabidopsis thaliana
… maintenance of existing methylation, and active demethylation as it utilizes these processes to facilitate gene expression changes throughout the lifetime of the plant. Expression of the DNA demethylase REPRESSOR OF SILENCING1 (ROS1) is dependent upon this balance as well as perpetuating …
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Identification and characterization of factors involved in DNA demethylation and anti-silencing in Arabidopsis
<p>DNA methylation is a key epigenetic mark for transcriptional gene silencing in many eukaryotes. DNA methylation status can be dynamically controlled by methylation and active demethylation processes. Compared to the well-known mechanisms of DNA methylation, the mechanisms of DNA demethylation …
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The Role of 5-Hydroxymethylcytosine in Genome Instability
… a critical epigenetic modification, and DNA methylation is involved in many biological processes. DNA methylation state is not static; hence, DNA demethylation mechanisms exist to remove 5mC from the genome. This is critical during developmental periods of widespread epigenetic …
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Dynamic regulation of DNA demethylation and RNA-directed DNA methylation in Arabidopsis
<p>DNA methylation is an important epigenetic mark present in many eukaryotes, and is involved in many crucial biological processes, such as gene imprinting, regulation of gene expression, and genome stability. Proper genomic DNA methylation patterns are achieved through the concerted action of DNA …
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Multi-omics characterisation of mouse gastrulation and organogenesis at single-cell resolution
… (1) the role of the spatial environment and (2) DNA methylation in cell lineage priming and specification during embryonic development. To better understand the spatial environment's role on cell fate specification (Aim 1), we used the image-based single-cell transcriptomics method, seqFISH, to …