Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Activatable probes"”.
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Development of chemical tools for studying biology with light: Photoactivatable donors and photoacoustic probes
… third chapter summarize our ap-proaches towards activatable contrast agents for photoacoustic imaging, an emerging deep-tissue imaging modality. To address a lack of modular activatable probes for this imaging technique, we combined the analyte specificity of DNA aptamers with commercially …
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Molecular imaging with engineered physiology
… existing imaging strategies and available probes have been limited by serious constraints. Magnetic resonance imaging (MRI) provides deeper tissue penetration depth than optical imaging and better spatial resolution and greater versatility in sensor design than radioactive probes. The most …
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Development of small molecule probes for fluorescence and photoacoustic molecular imaging
… use of reaction-based small-molecule fluorescent probes, a class of probes that exhibit differential fluorescence signals upon reacting with their intended target, has further rendered fluorescence imaging with good selectivity and higher sensitivity. Such reaction-based small-molecule fluorescent …
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Activatable photoacoustic contrast agents for sensing and delivering nitric oxide, and development of small molecule photoacoustic platforms with improved properties for in vivo imaging
… develop near-infrared, ratiometric photoacoustic probes for nitric oxide, with a focus on my contributions to the synthesis and in vivo studies (Chapter 2), as well as my work toward the synthesis and validation of our near-infrared photoactivatable nitric oxide releasing molecules (Chapter 3). I …