Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 19 of 19 for “"Action mechanism"”.
-
The molecular structures of chlorpromazine and thiethylperazine and a discussion of the action mechanism of the phenothiazine derivatives
… effects to develop a theory of their mode of action. The phenothiazines are divided into three groups according to the chemical nature of the side chain attached to the nitrogen atom:- (1), dimethylamino-propyl, (2), piperidine, and (3), piperazine radical. Chlorpromazine, pyscho-tropically …
-
The Effect of Topical Tranexamic Acid Application on Melasma Treatment
… of this study was to investigate the effects and action mechanism of topical TA in the treatment of melasma. Material and methods: Twenty three healthy Korean females with melasma were enrolled, and applied 2% TA formulation on the whole face for 12 weeks. Pigmentation and erythema were …
-
Design and manufacture of the quatraphone and composition of a short piece
… struck by a wooden mallet activated by a lever action mechanism. Vibration and damping of the rectangular plates were analyzed for various materials in order to determine which material produced the most musical tones. Brass and aluminum were selected for the quatraphone design. The final …
-
Manipulating Enhancer Rna Activity to Study Their Roles In Gene Regulation and Cancer
… eRNAs have a functional role in the enhancer action mechanism. Studying their roles will provide a new understanding of gene regulation and cancer development. In my MS study, I focused on using novel methods to study eRNA functions. Using a breast-cancer-specific eRNA, I have conducted …
-
Reshaping the Chinese Stock Market to Accommodate Red-chips: Practice, Balance and Consequence
… although the Chinese-style securities class action mechanism may provide a basis for some reorientation away from ex-ante regulation towards further market openness to attract red-chips. At a broader level, this thesis argues that the aim of better accommodating red-chips will be built …
-
Avaliação da atividade espasmolítica das partes aéreas e das raízes de Solanum paniculatum L.: um estudo comparativo.
… in smooth muscle models and elucidate action mechanism of the extract to present the better spasmolytic effect in one of the tested organs . Rat aorta: SP - EtOH PA and SP - EtOH R (243 and 729 μg/mL , n = 3) relaxed organ to pre - contracted with phenylephrine (3 x 10 - 7 M) in the …
-
Identification and functional study of the bioactive peptide QUB-2417 from the skin secretion of the tree frog, Phyllomedusa bicolor
… to develop resistance to AMPs because of their action mechanism. In this thesis, an AMP was identified from the skin secretion of Phyllomedusa bicolor, a tree frog from the Amazon rainforest, and was named QUB-2417. The peptide sequence was acquired by molecular cloning through constructing a …
-
Efeito do relaxamento induzido por diosgenina em artéria mesentérica de rato após administração de 17-β estradiol.
… further studies are required to clarify the action mechanism involved in this enhancement.
-
Effect of antidepressants and adolescent stress on catecholamine transmission in the rat bed nucleus of stria terminalis (BNST): a microdialysis study
… acute effects that antidepressants with varying mechanisms of action have on dopamine and norepinephrine output in the BNST; (ii) ascertain the acute effects that sub-anesthetic doses of ketamine have on dopamine and norepinephrine output in the BNST; (iii) ascertain whether peri-adolescent …
-
Membrane mechanism of progesterone actions on the rat brain
… areas of mammals. It is generally held that actions of stroids in the CNS are mediated via genomic mechanisms. However, there are at least three lines of evidence indicating that a nongenomic mechanism of P's action is also involved. First, P exerts effects on tissue preparations without …
-
Jaunųjų katalikų sąjūdžio genezė, ideologiniai principai ir jų realizavimo praktika (1919 - 1940) /
… – open („wide”) Catholicism and the Catholic Action (CA) became the basis of YCM religious programme. Meanwhile, the programme included the nation‘s efforts to seek for modernization of the country and the solidarity of nation. Refusal of traditional Catholicism exclusiveness enabled a …
-
DESIGN OF NOVEL ORGANIC MOLECULES AND METAL COMPLEXES WITH BIOLOGICAL PROPERTIES
… cytotoxicity at the micromolar level. Their mechanism of action was investigated through the study of the unfolded protein response (UPR) pathways, and in most cases, the results confirmed the activation of the pro-apoptotic branch of UPR suggesting the involvement of Endoplasmic reticulum …
-
A resonant mirror biosensor approach to understand antibody-antigen interactions in Guillain Barré Syndrome
… the severity of disease manifestation. The action mechanism of IVIg in curing GBS is not clear, but intravenous immunoglobulin was shown to neutralize anti-ganglioside binding activity and its pathogenic effects. It was further found that anti-idiotypic antibodies in IVIg inhibit …
-
Surfactant properties of corrosion inhibitors
… provides important information about their action mechanism, which in turn helps in improving their efficiency. The adsorption behaviour of CnBDMAC molecules has been studied as a function of the surfactant chain length, temperature and electrolyte concentration using the Quartz Crystal …
-
A new approach to ceramic lubrication: tribopolymerization
… at the contact region under the sliding action to form a protective layer at the contact. Selected monomers -- including one condensation type, C₃₆ dimer acid/ ethylene glycol monoester, and five addition type, i.e., lauryl methacrylate, diallyl phthalate, vinyloctadecyl ether, vinyl …
-
Analysis of Therapeutic Effect after Human Mesenchymal Stem Cell Transplantation in Ischemic Stroke Rat
… The proteomic profiles helped to explain the MSC action mechanism of stroke therapy. Part III: Mesenchymal stem cells (MSCs) have the potential to promote brain repair and improve recovery following stroke. I investigated changes in FFAs following intravenous human MSC (hMSCs) transplantation into …
-
Brain derived neurotrophic factor and structural vascular disease in black Africans : the SABPA study
… the specific functional role of BDNF and its action mechanism in the cardiovascular system, especially in that of Africans, is yet to be determined. The cardiovascular health profile of black South Africans is a major concern as research has shown that this group suffers from an array of …
-
Improved In Silico Methods for Target Deconvolution in Phenotypic Screens
Target-based screening projects for bioactive (orphan) compounds have been shown in many cases to be insufficiently predictive for in vivo efficacy, leading to attrition in clinical trials. Phenotypic screening has hence undergone a renaissance in both academia and in the pharmaceutical industry, …